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Author Topic: Factor that controls HIV latency  (Read 4990 times)

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Offline butpoz

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  • Posts: 27
Factor that controls HIV latency
« on: July 08, 2011, 11:39:50 pm »
They mentioned about an anti tumor drug azza-cdr thay may help activating the latent virus here http://www.scientistlive.com/European-Science-News/Biotechnology/Factor_that_controls_HIV_latency/22764/
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Offline OneTampa

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Re: Factor that controls HIV latency
« Reply #1 on: July 09, 2011, 07:13:26 pm »
Very interesting post.

Thank you.
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Offline Inchlingblue

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Re: Factor that controls HIV latency
« Reply #2 on: July 09, 2011, 08:58:49 pm »
Quote from: OneTampa on July 09, 2011, 07:13:26 pm
Very interesting post.

Thank you.

I agree.
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Offline dpb

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  • Posts: 89
Re: Factor that controls HIV latency
« Reply #3 on: July 10, 2011, 10:24:50 pm »
"While HIV-1 latency is likely to be a multifactorial process, we have shown that inhibiting the methylation of the provirus contributes to an almost complete reactivation of latent HIV-1," said lead author Steven E. Kauder.

"Combined with other areas of our investigation into HIV latency, this research provides important new knowledge about the process and opens many new pathways for future study," said Dr. Verdin, senior author of the study.

That's outstanding. 
« Last Edit: July 10, 2011, 10:32:42 pm by dpb »
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Offline MitchMiller

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Re: Factor that controls HIV latency
« Reply #4 on: July 17, 2011, 03:28:24 am »
http://cancerres.aacrjournals.org/content/63/16/4984.full

Procaine is a demethylating agent.  Given it is off patent, I would think it could be readily used in a publicly sponsored medical trial to at least demonstrate some efficacy in humans.
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Offline Coolio_7

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  • Posts: 66
Re: Factor that controls HIV latency
« Reply #5 on: July 18, 2011, 03:47:13 pm »
Sounds like it could be used against HIV. Could be promising. Now will they get this into some kind of clinical trial before the next 10 years :( I hope we have progress long before then.
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