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Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

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Recent Posts

Pages: 1 2 [3] 4 5 ... 10
21
Do I Have HIV? / Fingering multiple CSW with a cut and sore in the fingers
« Last post by Ahm08 on Yesterday at 01:11:11 pm »
Hi. First i want to thank you of what you and this forum done to people who was or were worrying about a exposure.
I fingered way too much womens deep inside the vagina. Some of the exposure i had a cut in my finger probably flesh cut after clipping my nails. It bled and even after fingering the next day my finger stings and when i applied pressure small blood came out. Now my fingers are not in good condition. I really dont take care of my fingers. I bite the skin near the nails. There is a gapping space between the side of my nails and fingers. There is alot of scrapes underneath my fingernails.
Every time i finger a CSW i get stinging pain in my fingers but no blood.
- what is the risk of fingering multiple womens probably around 20.
- i read air inactivates the HIV, but i fingered her deep inside till the cervix and rubbed the area without taking my finger out. So there is no air. With a fresh cut under my nails. Im afraid while my finger was inside and i let it there for awhile, the virus mite have entered throught that cut.
- as i said my finger are not in good condition and i still finger them. From all the websites i read fingering is a low risk if you have a fresh cut.
- is there target cell in the fingers where hiv attach to it like in the penis or the vagina and anus.
22
Estoy infectado? / Re: san2023
« Last post by Jim Allen on Yesterday at 01:09:59 pm »
Cualquier los detalles recibiendo el sexo oral es sin riesgo por el VIH, carece de las condiciones necesarias para que el VIH.

Adelante con su vida.


23
Estoy infectado? / Re: san2023
« Last post by san2023 on Yesterday at 01:07:26 pm »
Hola buenas ….tenido relacion sexo oral con mujer recibido sexo oral
No dado cuenta ella tiene algo in boca tipo grano
So tengo que hacer prueba gracia
24
Do I Have HIV? / Exposure Question
« Last post by Any1122 on Yesterday at 12:57:10 pm »
Hello, perhaps I am overthinking this and it’s from a lack of knowledge. But question about possible exposure revolves around some incidents of my doing. About 60 hours ago I engaged in some activities with a female sex worker. We did kiss, then She gave me unprotected oral sex, I fingered her, and then had intercourse with her whilst wearing a condom that I put on myself. I did have some alcohol in my system, and I am pretty positive the condom did not fail (maybe I could’ve missed something? Idk) but it definitely was on the majority of my genitalia. Her status is unknown to me. Would it be smart to take PEP or am I just completely being anxious over nothing?
25
Research News & Studies / Re: A class of HIV drugs might protect against Alzheimer’s
« Last post by Jim Allen on Yesterday at 12:32:56 pm »
Previous related topics.
 
HIV Treatment Mitigates Risk of Early Onset Alzheimer’s Disease
https://forums.poz.com/index.php?topic=74746.msg

HIV Medication Epivir Could Possibly Treat Alzheimer’s
https://forums.poz.com/index.php?topic=74746.msg
26
Research News & Studies / A class of HIV drugs might protect against Alzheimer’s
« Last post by Jim Allen on Yesterday at 12:29:23 pm »

Aidsmap article in full: https://www.aidsmap.com/news/may-2024/class-hiv-drugs-might-protect-against-alzheimers

In Brief:

Quote
A cohort of people with HIV who took NRTIs (a class of HIV drugs) as part of HIV treatment showed lower rates of Alzheimer’s disease than people without HIV.

Nucleoside reverse transcriptase inhibitors (NRTIs) are a class of drugs that block HIV’s RT enzyme. Since HIV’s RT is similar to the RTs produced in our cells, these same drugs may have the potential to block them too, possibly protecting against Alzheimer’s disease.

The researchers collected data on three cohorts of people – those with HIV taking NRTIs; those with HIV either on an NRTI-free regimen or off treatment; and a third cohort who were not living with HIV nor taking NRTIs. They followed up each cohort for two years and nine months to see whether NRTIs reduced the rate of Alzheimer’s.

The data came from a large number of people, which reduces the likelihood of these findings being a chance event. Over 46,000 people were included in the cohort of those with HIV on NRTI-containing regimens. There were 33,000 people in the cohort of people with HIV not taking NRTIs and 151,000 people in the cohort without HIV and not taking NRTIs.

During the two years and nine months of follow-up, the rate of developing Alzheimer’s was lowest in the first cohort – people with HIV on an NRTI-containing regimen. In this cohort only 2.46 in 1000 people developed Alzheimer's disease.

In the second cohort of those with HIV either on an NRTI-free regimen or off treatment the rate of Alzheimer’s was higher compared to the first cohort, but still lower than the third cohort of those without HIV. However, the difference between this cohort and those without HIV became insignificant when age and sex were added to the analysis. In this cohort the rate of Alzheimer’s was 3.55 in 1000 people.

The third cohort had the highest rate of Alzheimer’s at 6.15 in 1000 people.

Interestingly, a further analysis of the first cohort revealed an increased rate of Alzheimer’s in those taking protease inhibitors (another class of HIV drugs) alongside their NRTIs. However, the difference was not statistically significant and it would be early to make any conclusions.

Last but not least, this was a retrospective study (one that collects data on the past medical records of people). Besides, it has a set of limitations such as a relatively short follow-up period and non-ideal match between cohorts with regards to age and sex. Randomised controlled studies would be required to get a more definitive answer to whether NRTIs protect against Alzheimer’s disease in people without HIV.
27
Off Topic Forum / ‘I felt like I was dirty’: experiences of gay men diagnosed with mpox
« Last post by Jim Allen on Yesterday at 12:21:15 pm »

Aidsmap article in full:
https://www.aidsmap.com/news/may-2024/i-felt-i-was-dirty-experiences-gay-men-diagnosed-mpox-england

In Brief:

Quote
A recent study found that men diagnosed with mpox, clinicians and community stakeholders believe that the government's perceived inaction towards the illness was due to its association with stigmatised sexual minorities. This systemic failure was often compared to the initial response to the AIDS crisis.

With the exception of an Australian study, there has been limited qualitative research on the patient experience of mpox. To better understand the social and clinical support needs of people with mpox, researchers from University College London conducted interviews with 22 gay and bisexual men who were diagnosed with monkeypox in England in 2022. The researchers who conducted the interviews were also cisgender gay men.

During the 2022 outbreak, HIV-negative gay and bisexual men who had little experience with stigmatising illnesses found their mpox diagnosis to be particularly traumatic and a personally threatening experience. They often required additional support beyond what was available. However, men living with HIV seemed to handle the stigma better, drawing on resilience from past experiences with HIV.

Mpox was associated with significant feelings of stigma, particularly due to homophobic narratives that linked promiscuity with illness and disease. Some men were also discriminated against by sexual contacts, online, and in healthcare settings. All men who had contact with non-specialist hospital services (such as Accident and Emergency) after receiving an mpox diagnosis reported some degree of enacted stigma from staff, usually related to infection control measures.

Conclusion
The lack of cultural competence in some health services that catered to gay and bisexual men resulted in stigmatisation and, at times, distress. This highlights the importance of involving members of affected communities in co-producing, planning and delivering care – including contact tracing, where stigma is likely to be a significant barrier to engagement.

“This should be done continuously from the outset of outbreaks and be accompanied by appropriate funding, especially for community-based organisations who often face financial precarity,” the authors conclude.


28
Research News & Studies / Re: EBT-101
« Last post by Jim Allen on Yesterday at 11:56:49 am »
I have not seen all the details yet, but if correct it's a flop in terms of an HIV cure, even the one patient out of five reaching 16 weeks is nothing to praise with standard modern ART. *

Excision’s CRISPR-Based HIV Treatment Fails to Show Curative Potential in Early Study

https://www.biospace.com/article/excision-s-crispr-based-hiv-treatment-fails-to-show-curative-potential-in-early-study-/

Quote
Excision BioTherapeutics’ attempt to use a CRISPR-based gene editing therapy to cure HIV has failed an early-stage study, according to several media reports on Friday.

Results from the Phase I trial of five patients showed that Excision’s CRISPR therapeutic did not strongly suppress the HIV virus. Three patients who were taken off of antiretroviral therapy soon developed viral rebound and needed to resume conventional treatments, according to reporting by STAT News.

Still, Excision’s approach did show signs of promise. One patient was able to keep the virus at bay for 16 weeks after stopping antiretroviral treatment before rebounding.

I'll keep my eyes open for more details when they become available and post them here.


* HIV Time to Viral Rebound After Interruption of Modern ART.
https://forums.poz.com/index.php?topic=76642.msg
29
Forums Gatherings / Re: Biweekly Peer Support Call
« Last post by Jim Allen on Yesterday at 11:11:06 am »
Quote from: numbersguy82 on Yesterday at 09:41:26 am
It’s always so great to connect with others on here, but sadly I’ve lost sight of what I wanted for these meetings. I think perhaps our mission and numbers would be stronger under someone else’s guidance. There is value in a clinical discussion from a shared perspective. Likewise, community and fellowship are vital to maintaining a positive future outlook. I hope everyone here finds that great future- be it from our one time posters, to the lurkers who read only, or to the few regulars who actively participate to make this space so wonderful.

I'm sorry to hear this and want to thank you for the leadership & care you put into this and thanks to everyone who worked to support these calls.

I feel we still need a separate call dedicated to Peer support and HIV updates (News) but it is something I will get back to you and the others on at a later date.

Quote
I look forward to connecting with everyone on the monthly virtual gatherings. If you aren’t participating in those, they are great fun.

 :) Absolutely, the monthly calls certainly are fun and a nice way to connect and catch up with each other.
https://forums.poz.com/index.php?topic=77368.0

30
Forums Gatherings / Re: Biweekly Peer Support Call
« Last post by numbersguy82 on Yesterday at 09:41:26 am »
It’s always so great to connect with others on here, but sadly I’ve lost sight of what I wanted for these meetings. I think perhaps our mission and numbers would be stronger under someone else’s guidance. There is value in a clinical discussion from a shared perspective. Likewise, community and fellowship are vital to maintaining a positive future outlook. I hope everyone here finds that great future- be it from our one time posters, to the lurkers who read only, or to the few regulars who actively participate to make this space so wonderful.


I look forward to connecting with everyone on the monthly virtual gatherings. If you aren’t participating in those, they are great fun.
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