New drug holds out promise of long-term control or even cure of HIV

[Zoob626]

Is this real cure  ??
New drug holds out promise of long-term control or even cure of HIV
Scientists at the Scripps Research Institute in California have discovered a new type of drug that may permanently inhibit HIV from becoming reactivated in the cells that are chronically infected with it. The new drug, didehyro-cortistatin A (dCA), appears to permanently change the cellular environment so that even after it is removed, the cells of the latently-infected reservoir cells remain 100 times less likely to ‘wake up’ and start producing new viruses.

This drug fills a gap in the anti-HIV arsenal that researchers have been in search of for a long time: it is an effective, apparently non-toxic and potent tat inhibitor.

To read more here is link
http://www.aidsmap.com/New-drug-holds-out-promise-of-long-term-control-or-even-cure-of-HIV/page/2985232/

[Almost2late]

I think I read about this recently somewhere else but they used the term "remission" to describe what this drug does to hiv in the latent reservoir.. This is really good stuff..

So what if you used the "shock&kill" drug first, flushed out as much of the virus as possible and kill it with ARV.. once ud, then use this new drug and freeze the remainder of the virus that might be left over in the reservoirs..

I'm no scientist but maybe using a combination of these new discoveries might lead to a therapeutic functional cure.. hope so.

[Ptrk3]

Freewillie99 posted what seems to be similar research done at Scripps in Florida last week.  I presume these researchers talk to one another, since they seem to be dealing with a similar, if not same, drug prospect (Cortistatin A):

http://www.eurekalert.org/pub_releases/2015-07/sri-srd070815.php

Both these efforts seem to be promising but there's not much information about how long before these efforts will be ready for clinical trial (months?  years?), at least as far as I can tell.  I hope there is some urgency with both these efforts and that they can be joined where and if appropriate.

[tryingtostay]

Oh the torture HIV will go through with this

[DANIELtakashi]

Thank you for the info.
Thrilling.