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Author Topic: Engineered B cells in Mice produce broadly neutralizing anti-HIV antibodies  (Read 1874 times)

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Offline Jim Allen

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Early days and we know most of these things don't pan out but an interesting read, although, the media hype around this one is the usual nonsense::)

A study by Dr. Adi Barzel and PhD student Alessio Nehmad used CRISPR gene-editing genetically engineered type B white blood cells (with one coding for Staphylococcus aureus Cas9 (saCas9) and the other for 3BNC117, an anti-HIV bNAb) to produce neutralizing antibodies against HIV in mice and lab dishes.



In Full: Thanks to genengnews.com.


Another study using an anti-HIV-1 antibody for viral suppression was also recently posted:

Viral suppression with anti-HIV-1 antibody - Phase 1b 3BNC117 & 10-1074
« Last Edit: June 15, 2022, 11:05:57 am by Jim Allen »
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Offline jeju

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Researchers at Tel Aviv University have developed a new and unique treatment method that could possibly be developed into a vaccine or a one-time treatment for HIV/AIDS. The new technique utilizes type B white blood cells that would be genetically engineered inside the patient's body to secrete anti-HIV antibodies in response to the virus.

« Last Edit: June 15, 2022, 11:30:02 am by Jim Allen »
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Offline Da2020

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Canít agree more with media nonsense. They havenít even tested it in vivo


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