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Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

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Recent Posts

Pages: 1 [2] 3 4 ... 10
11
How Can I Prevent HIV? / Re: I need urgent help. 😭
« Last post by Jim Allen on Yesterday at 08:45:37 am »
Quote
I lived for 4.5 months without treatment and now I've been on treatment for 1 month. I'm using Biktarvy. Is 4.5 months considered late?

No.

Treatment is recommended to start as soon as possible where and when its possible and appropriate, however, 4.5 months isn't a big delay and your results are great. Biktarvy is first-line treatment or as some members call it the "VIP treatment".

Give it a few more months and the remaining VL will be fully suppressed (below 200 copies). After that counting the CD4s is rather irrelevant and once you have a fully suppressed VL for six+ months and keep taking your treatment it also means you can't pass on HIV sexually. See detail here: https://forums.poz.com/index.php?topic=71864.0

Quote
My second question is: should I firmly believe that it won't be transmitted to my family? Even in a scenario where semen on the toilet seat came into contact with my father's penis, would this still be the case?

Asked and answered already  ;)

Your father will only have HIV if he has been sharing syringes or engaging in condomless sex.
12
How Can I Prevent HIV? / Re: I need urgent help. 😭
« Last post by Babacanfatih on Yesterday at 08:38:35 am »
Jim, I am grateful to you for writing in such detail for me. I lived for 4.5 months without treatment and now I've been on treatment for 1 month. I'm using Biktarvy. Is 4.5 months considered late? My second question is: should I firmly believe that it won't be transmitted to my family? Even in a scenario where semen on the toilet seat came into contact with my father's penis, would this still be the case? Thank you, Jim.


13
How Can I Prevent HIV? / Re: I need urgent help. 😭
« Last post by Jim Allen on Yesterday at 08:29:44 am »
Thanks for the update.

The results are good. 570K wasn't very high to begin with but a drop to 1200 is good and means treatment is working, give it a few weeks/months and the viral load should be fully suppressed (Below 200 copies) The CD4s are great.

Quote
Now, my family is very sick, and we are experiencing the same  symptoms

I presume you have not been sharing syringes or having condomless sex with your family members, so whatever symptoms you & your family are experiencing have nothing to do with your HIV status.

Quote
I was frequently masturbating into the toilet. Sometimes I cleaned it, but sometimes I forgot.
Quote
Now I am asking, could it have been transmitted to my family?

Zero chance you gave your family HIV by sharing a toilet regardless of what fluids you left on it. 

Decades ago, toilet HIV risk concerns were busted, partly because HIV is too fragile as once exposed outside the confines of the human body, the receptors corrode leaving HIV unable to infect, so it's not an HIV risk, nobody has ever acquired HIV from using a toilet.

Common Myths About How HIV Is Spread
https://forums.poz.com/index.php?topic=68441.0

5 of the weirdest HIV transmission myths
https://www.beintheknow.org/news-and-blogs/5-weirdest-hiv-transmission-myths-ever

Quote
could it have been transmitted to my family?

In brief, your family will only get HIV from:

* Condomless intercourse & a minute (theoretical) HIV to the person giving the blowjob.
* Sharing drugs rigs (Syringes)
* Blood products/ transfusions (Rare nowadays in most nations thanks to screening)

That's it.


14
How Can I Prevent HIV? / Re: I need urgent help. 😭
« Last post by Babacanfatih on Yesterday at 08:21:14 am »
Hi jim , When I was first diagnosed, my RNA count was 570,000 (LYM% 39.6 and LYM# 2.59). In my most recent tests, my RNA count is 1,200 and my CD4 count is 750.
I am using Biktarvy.

15
How Can I Prevent HIV? / Re: I need urgent help. 😭
« Last post by Jim Allen on Yesterday at 07:57:06 am »
Hiya.

Just want to confirm you are living with HIV?

What treatment are you taking and what was your latest viral load & CD4 counts?
16
How Can I Prevent HIV? / I need urgent help. 😭
« Last post by Babacanfatih on Yesterday at 07:16:48 am »
"Hello, I lived with my family for 4 months without knowing I was HIV positive. I was frequently masturbating into the toilet. Sometimes I cleaned it, but sometimes I forgot. Now, my family is very sick, and we are experiencing the same  symptoms, and I am very scared. While doing this, I was in the acute phase and probably had a high viral load. Now I am asking: the toilet seat is very narrow, and there is an area where the penis touches when sitting.  and sperm was spilled there. Now I am asking, could it have been transmitted to my family?"  I would like to point out that the incident is serious and my family has been sick for a long time.
17
Do I Have HIV? / Re: Please kindly help me
« Last post by Jim Allen on Yesterday at 05:31:13 am »
If you read back your thread this has been already answered.

Anyhow, a nonreactive result on a blood drawn laboratory HIV antibody test six weeks post potential exposure is generally considered confirmed and retesting at three months is generally not necessary. Being in the UK doesn't change that.

You have tested six+ weeks post potential exposure, it's nonreactive, you don't have HIV, time to move on with your life.
18
Do I Have HIV? / Re: Please kindly help me
« Last post by parysUK on Yesterday at 05:12:21 am »
So my 46 days after exposure 16/8 out of window test   all came back clear .
Blood drawn from the vain in Sexual clinic amd send to the lab 4th gen test I live in UK
Could I kindly ask if that’s all testing done for re HIV as I haven’t had any contact with anyone since 16/8
I spoke  with health adviser and she said that no more testing is required as in uk the window period is 45 days .
I just want to put all the subject to sleep and move on and start my daily prep .
However some organisations recommend 8 week window and it can be bit confusing 😩
I would really appreciate answer
19
Living With HIV / Re: Urgent surgery - skipping dose of Odefsey
« Last post by Jim Allen on Yesterday at 04:22:38 am »
Again, good luck today and keep us posted, I wish you a speedy recovery.
20
Living With HIV / Re: Urgent surgery - skipping dose of Odefsey
« Last post by Jim Allen on Yesterday at 04:21:23 am »
Sorry to hear about the back pain and I hope the surgery goes well today. Please keep us posted.

As for missing the meds today, I presume your medical team knows and it doesn't make any difference.

You are on Odefsey, so triple therapy and for triple therapy perfect adherence is considered taking your meds 95%+ of the time on time. So even if you miss the odd pill it would still be ideal adherence (Not that I recommend skipping pills, if avoidable, but sometimes it happens or is needed)

Quote
Im now afraid it will fuck up my arv theraphy.

So you will not fuck up your treatment by skipping one pill today. Missing a dose for whatever reason is a common enough concern, included some previous threads on the topic as you might find them useful/reassuring.

Adherence
https://forums.poz.com/index.php?topic=73377.msg

https://forums.poz.com/index.php?topic=64111.msg

https://forums.poz.com/index.php?topic=71153.msg


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943894/
Adherence and virologic outcomes among treatment-naïve veteran patients with human immunodeficiency virus type 1 infection

A cohort study was conducted on HIV veterans initiating antiretroviral therapies in 1999 to 2015

In summary, this study showed how initial adherence differently influenced the viral suppression rate across different regimens. No evidence shows 95% adherence threshold is necessary. Patients with medium adherence (75%–<95%) can achieve viral suppression with the rate not statistically significantly different from patients with high adherence.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839839/
Adherence to Antiretroviral Therapy and Virologic Failure

Paterson et al suggested that at least 95% adherence to unboosted PIs was required for virologic suppression. This 95% adherence cut-off point, based on what is now obsolete therapy, has been widely used as the level of optimal adherence needed to be met by patients taking newer agents and their combinations.

This meta-analysis synthesized 43 studies (27,905 participants) performed across >26 countries, to determine the relationship between cut-off point for optimal adherence to ART and virologic outcomes.

Irrespective of the cut-off point for optimal adherence, our findings support the tenet that optimal adherence to ART is associated with positive clinical outcomes. The threshold for optimal adherence to achieve better virologic outcomes appears to be wider than the commonly used cut-off point (≥95% adherence). Though patients taking ART should be instructed to attain ≥95% adherence, apprehensions of slightly lower adherence should not deter prescribing ART regimens at an early stage of HIV infection.


https://journals.lww.com/jaids/Abstract/2019/11010/Antiretroviral_Adherence_Level_Necessary_for_HIV.3.aspx

Antiretroviral Adherence Level Necessary for HIV Viral Suppression Using Real-World Data

A benchmark of near-perfect adherence (≥95%) to antiretroviral therapy (ART) is often cited as necessary for HIV viral suppression. However, given newer, more effective ART medications, the threshold for viral suppression may be lower. We estimated the minimum ART adherence level necessary to achieve viral suppression.

Results: The adjusted odds of viral suppression did not differ between persons with an adherence level of 80% to <85% or 85% to <90% and those with an adherence level of ≥90%. In addition, the overall estimated adherence level necessary to achieve viral suppression in 90% of viral load tests was 82% and varied by regimen type; integrase inhibitor- and nonnucleoside reverse transcriptase inhibitor-based regimens achieved 90% viral suppression with adherence levels of 75% and 78%, respectively.

Conclusions: The ART adherence level necessary to reach HIV viral suppression may be lower than previously thought and may be regimen-dependent.

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