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Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

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Recent Posts

Pages: [1] 2 3 ... 10
1
Living With HIV / Re: Understanding cd4/cd8 ratios
« Last post by Matths on Today at 07:23:21 am »
Hi, let me give this a try. When you were diagnosed a low CD4/8 ratio could be explained by low CD4 numbers as direct result of HIV negatively impacting the absolute CD4 count. In most cases combined with high CD8 numbers. The CD8 cells are the storm troopers fighting infection of any sort and are a marker of an activated immune system. As you have correctly pointed out, CD8 activation is also found in other situations when the immune system is (over)active, ie MS, cancer etc.

In HIV, especially once you are on ART that controls HIV and brings you to U, your CD4 counts will slowly increase and CD8 activation will end and counts decrease. Therefore, even when your absolute CD4 numbers may not increase back to a normal range (as defined by healthy people’s numbers), because CD8 numbers decrease your ratio will increase towards normal. During situations of an infection or any other situation that requires your immune system to react, you will see a transient increase in CD8 numbers suggesting a healthy immune response. Such healthy response can result in a transient decrease of the ratio CD4/8, but is nothing you should worry about.

Overall, you want to ensure you are U and shouldn’t worry much about the fluctuations in your CD4 and 8 numbers, and their ratio.

Hope this makes sense, best Matt
2
Off Topic Forum / Re: Unexpected travel to the Netherlands
« Last post by Grasshopper on Today at 04:16:38 am »
Hi Jim, hope you managed to fly back with your son without any troubles at the airport or on the airplane.

Those nightmares....I feel for you, and I can relate. Talked to you GP and asked for something to "put a brake on your mind" so you can at least get a good rest/sleep ?

It's so easy for people to say live in the now and deal with the future when it comes...but that is impossible.

Ik wens je sterkte en wijsheid....hou je sterk...uiteindelijk komt er een oplossing.

Groet
3
Off Topic Forum / Re: Any of the old school members still lurking?
« Last post by skeebo1969 on Today at 03:18:24 am »
Hi, bummer....wishing you a speedy recovery

It's been an ordeal of sorts, but feeling better than I was.. thanks.



Damn Thomas,....Really sorry to hear you went through this. I thought I remember you mentioning that you were dealing with Diverticulitis, at one time here on the forums. Wishing you a very speedy recovery on all this.
I am sure it was a very difficult time for you.

I've only known one a person dealing with Diverticulitis, and he was in his 80's and was doing well with dietary control.


Take care -- Ray 

I've been dealing with it since 1998.  It comes and goes, but the last 3 years have been bad.  I picked a wrong time for it to take a turn for the worse.  Lack of beds in the hospital due to Covid had me waiting for 8 days to get treatment, and the infection only got worse.  I take my meds and they come out the same way they went in oddly... I know too much information lol.  Today wasn't especially terrible...  sitting here enjoying a hearty bowl of beef broth.  Sucks.  I want some fried fish, grits, and collard greens...  Hopefully by Christmas.
4
Living With HIV / Re: Understanding cd4/cd8 ratios
« Last post by Almost2late on Today at 02:46:57 am »
Thank you Bucklandbury, I appreciate your insight.

So from what I'm understanding here, for every cd8 we PLWH should have at least two cd4's?.. and normal for negatives is four cd4's for every single cd8 or better?

I know I'm screwing this up.. I'm terrible at fractions or algebra, or whatever this is. But I do know that on my last test that measured my cd8 ratio was in 2018, and it was 0.3.. does that mean cd8's outnumber cd4's 3 to 0?.. and that can't be good, right?. Lol, i hate math. Maybe explaining like I was 5yrs old rather than 12.

But thank you..
5
Living With HIV / Re: Approaching 5 years Positive
« Last post by daveR on Yesterday at 10:53:41 pm »
dave,

im on biktarvy also,, 4 years in, alls well here now for me too... im motivated to hear about your thai life and experience liveing with hiv here, as in the back of my mind thailand has always been my fall back in the event healthcare here for me becomes unaffordable.   i beleive biktarvy is 3000 plus USD here right now,, so i am really excited to see this 3600 tHB price....how much does the rest of healthcare cost since your out of pocket, paying cash there???  I have a wife and 1 daughter i need to bring with me also if we make the move,, they are i full support and willing to go move there with me if i choose, thank goodness.
That is a very broad question. I use private hospitals, the one I use now is the most expensive in the area. This doesn't mean I get the best medical treatment, it just means I get a very convenient polite service. Instant consultations and a Starbucks in the hospital lobby. I could get treatment at a government hospital much cheaper, but without any luxuries attached. Coming from the UK any treatment I have to pay for is expensive, so even at 3600 Thai baht, or just over $100 for a month of Biktarvy makes me want to cry.
If you do settle here with the family, HIV treatment in Bangkok is much cheaper at the Thai Red Cross, and health insurance for your family is essential. You wouldn't really want your loved ones spending time in a government hospital, communal ward recovering from an operation.

Dave
6
Off Topic Forum / Re: Unexpected travel to the Netherlands
« Last post by Tonny2 on Yesterday at 08:16:50 pm »



            ojo.          Hi Jim, I’m sorry to read what’s happening with your son. I couple, friends of mine, right now is having that dilema, what to do with James, same problem than your son, but James now is 18 years old, heavy and strong, so strong that his father can not control him anymore. So, I understand you being concerned, my friends still want to keep him with them but, they have thought about your nightmares, taking him to an institution to take care of James…I think that at the end, my friends will do what is best for the three of ten, because it is so difficult for the whole family keep living the way they have been living.

If you want to talk to my friends about how they have been dealing with James through the years, maybe they can share experiences that they might be help you with your son. I think your son is still a small child, isn’t he?…best wishes and good luck when you pick him up in the Netherlands…hugs
7
Off Topic Forum / Re: Unexpected travel to the Netherlands
« Last post by Ptrk3 on Yesterday at 02:22:21 pm »
I'm sorry to hear of your troubles, Jim.  You are a fine father and a very good man.

I wish you the very best.
8
Off Topic Forum / Re: Unexpected travel to the Netherlands
« Last post by virgo313 on Yesterday at 12:58:50 pm »
Hi Jim, I do not have children & won’t be able to say much. Hope you will think one day at a time. Love will replace “how to manage” when times come. Safe trip Jim.
9
Living With HIV / Re: Understanding cd4/cd8 ratios
« Last post by Bucklandbury on Yesterday at 12:17:01 pm »
I'm not an expert, but:

A normal CD4/CD8 ratio is 2.0, with CD4 lymphocytes equal to or greater than 400/mm3 and CD8 lymphocytes equal to 200 to 800/mm3.

If your ratio is higher than 2, it means your immune system is strong and you may not have HIV.

If your ratio is less than 1, you may have:

HIV
AIDS - if your CD4 count is less than 200/mm3
Bone marrow problems related to chemotherapy
Anemia
Multiple sclerosis, myasthenia gravis, or another nervous system condition
Chronic infection

Higher than normal results may mean you have:

Major infection
Viral infection
Type of blood cancer

So... my limited understanding is that (ideally), we as PLWH want this ratio to be as close to 1.0 as possible, without going too much under or over.

Someone more knowledgeable, please correct me.

Thank you.
10
Living With HIV / Re: Approaching 5 years Positive
« Last post by TGun on Yesterday at 10:01:03 am »
dave,

im on biktarvy also,, 4 years in, alls well here now for me too... im motivated to hear about your thai life and experience liveing with hiv here, as in the back of my mind thailand has always been my fall back in the event healthcare here for me becomes unaffordable.   i beleive biktarvy is 3000 plus USD here right now,, so i am really excited to see this 3600 tHB price....how much does the rest of healthcare cost since your out of pocket, paying cash there???  I have a wife and 1 daughter i need to bring with me also if we make the move,, they are i full support and willing to go move there with me if i choose, thank goodness.

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