Meds, Mind, Body & Benefits > Nutrition & HIV

Any advice for nutrition or supplements for neurological health

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Lorenzopier:
It looks like to me because you can't understand or comprehend what it is that I do for my own personal health reasons you are trying to come up with a way to say it is somehow dangerous or snake oil. By the way, just because something is not supported by medical science does not mean it is snake oil or can not be used to benefit a person either.

zach:
And none of what you just posted does anything to support your original recommendations

You put out an asthma medication as a micronutrient with cognitive benefits

Support that claim with specific medically supported evidence

Meanwhile, I call bullshit snake oil

Lorenzopier:
https://www.smartpatients.com/trials/NCT02505477

Treatment of Cognitive and Negative Symptoms in Schizophrenia With N-acetylcysteine

The purpose of this study is to attempt to treat cognitive and negative symptoms of schizophrenia, with the nutritional supplement N-acetylcysteine (NAC).

Schizophrenia is a chronic mental disorder that affects approximately 65 million people worldwide, and causes significant disability and suffering. Patients with schizophrenia often hear voices and have persecutory delusions. Though these are the most recognizable features of the illness, the deficits most closely linked to disability are known as cognitive deficits and negative symptoms. Cognitive abilities refer to the ability to perform mental tasks that require focus and attention, and also include memory and verbal skills. Negative symptoms refer to a lack of interest in the world, and decreased social interactions. In our study, the investigators aim to improve these symptoms and deficits by targeting the glutamate system.

Glutamate is the major excitatory neurotransmitter in the brain, and its regulation is abnormal in schizophrenia: glutamate levels are too low at some receptors, and too high at others. As well, free radicals surrounding glutamate receptors also interfere with their proper function. N-acetylcystine (NAC) is a safe and widely-available dietary supplement that may restore glutamate to its correct levels in the brain, and may also help protect the brain from antioxidant damage.

Lorenzopier:
https://www.semanticscholar.org/paper/The-effect-of-N-acetylcysteine-(NAC)-on-human-%E2%80%93-A-Skvarc-Dean/428eabd7234ab5c4681076a27add57681e4a5452

The effect of N-acetylcysteine (NAC) on human cognition A systematic review

N‐acetylcysteine (NAC) is a glutathione precursor with potent antioxidant, pro‐neurogenesis and anti‐inflammatory properties and a favourable safety profile. A systematic review of the literature specifically examining the effect of NAC administration on human cognition revealed twelve suitable articles for inclusion: four examining Alzheimer's disease; three examining healthy participants; two examining physical trauma; one examining bipolar disorder, one examining schizophrenia, and one examining ketamine‐induced psychosis. Heterogeneity of studies, insufficiently powered studies, infrequency of cognition as a primary outcome, heterogeneous methodologies, formulations, co‐administered treatments, administration regimes, and assessment confounded the drawing of firm conclusions. The available data suggested statistically significant cognitive improvements following NAC treatment, though the paucity of NAC‐specific research makes it difficult to determine if this effect is meaningful. While NAC may have a positive cognitive effect in a variety of contexts; larger, targeted studies are warranted, specifically evaluating its role in other clinical disorders with cognitive sequelae resulting from oxidative stress and neuroinflammation.

xrel0aded:
Algae Oil.

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