UPDATE: Needle found in Sandwich on Delta Results in PEP taken by Passenger

[Ann]

I know Truvada is used for PrEP, but is it now standard treatment for PEP?  Everyone I've worked with that has had a needle-stick incident has always been given AZT and two other drugs.

Truvada plus Kaletra once a day has been the standard of care (PEP) in the UK for a few years now. It got changed around the same time as AZT got pulled from the preferred first line treatments for us pozzies. AZT is still listed as a possible alternative, but Truvada plus Kaletra is the recommended, preferred combo.

Here are the British guidelines. (pdf)

I thought the US guidelines had also been changed, but I did some digging and discovered that they're still recommending Combivir (twice a day, containing AZT). I wondered why one of the articles referred to Truvada being prescribed "off label" for PEP. It would seem clinical recommendations need to catch up with clinical practice in the US.

In case you're wondering, sometimes only two NRTIs are prescribed instead of a triple drug, dual-class combo when the risk is perceived to be low.



edited to fix broken linky

[emeraldize]

http://today.msnbc.msn.com/id/48209579/ns/travel-news/

now there aren't even any names of needle finders mentioned in the story nor Truvada nor HIV -- that's more like it

[Rhaegar]

In case you're wondering, sometimes only two NRTIs are prescribed instead of a triple drug, dual-class combo when the risk is perceived to be low.

This makes sense.  Thanks for the info, Ann.  I may not always post/comment here, but I always enjoy reading your posts.

-Kevin

[Ann]

This makes sense.  Thanks for the info, Ann.  I may not always post/comment here, but I always enjoy reading your posts.

-Kevin

You're welcome (and sorry to hear about your sore butt).