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Author Topic: DHHS Updated HIV Treatment Guidelines  (Read 1277 times)

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Offline Jim

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DHHS Updated HIV Treatment Guidelines
« on: November 17, 2024, 03:41:41 am »
POZ.com Summary

DHHS guidelines


Some updates in brief:

The Panel made the following changes to the recommended initial ART regimens:

Triumeq - Dolutegravir (DTG)/abacavir(ABC)/lamivudine(3TC) has been changed from one of the Recommended Initial Regimens for Most People With HIV to a regimen recommended as part of Other Initial Antiretroviral Regimens for Certain Clinical Scenarios due to the need for HLA-B*5701 testing before initiating therapy, the potential increase in the risk of cardiovascular events (ABC), and the availability of other options for initial therapy.

Several antiretroviral (ARV) regimens are no longer recommended as initial therapy due to higher pill burdens, more adverse effects, or a lower barrier to resistance than other ART regimens recommended by the Panel. These regimens include the following:

Elvitegravir/cobicistat and raltegravir-based regimens
Boosted atazanavir-based regimens
Efavirenz-based regimens
Rilpivirine (RPV)/tenofovir disoproxil fumarate/emtricitabine (FTC) regimens

Drug-Drug Interactions updated with new PK data on interactions between ARV drugs and other drugs

You can find the 2024 drug chart here


« Last Edit: November 17, 2024, 03:45:04 am by Jim Allen »
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