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Author Topic: Truvuda PEP side effects  (Read 471 times)

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Offline landersen

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Truvuda PEP side effects
« on: September 07, 2022, 12:35:23 pm »
Apologies if this has been covered elsewhere.  New here and couldn't really find what I was looking for via search.

I just took my first Truvada and Inestress pills for PEP treatment.  Generally speaking, when I read about potential side effects, I'm wondering how severe those side effects are in the real world.  I'm a relatively healthy 52 year old male.  Only real issue I have is being roughly 25lbs overweight.

Is there any advice for these drugs to help mitigate potential side effects such as Nausea, diarrhea, etc?

I am a little concerned that I sometimes do suffer very mild bouts of depression and wondering how concerned I should be about that since it is a listed side effect of Truvada.

Thoughts are advice from the community?

Thank you in advance.

Online Jim Allen

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Re: Truvuda PEP side effects
« Reply #1 on: September 07, 2022, 12:43:56 pm »
Why are you taking PEP?

I also moved your post here, as the section you posted originally is designed for people living with HIV.

Quote
Generally speaking, when I read about potential side effects, I'm wondering how severe those side effects are in the real world.

Quote
Is there any advice for these drugs to help mitigate potential side effects such as Nausea, diarrhea, etc?

Truvada (TDF/FTC) is not required but is best taken with food to reduce certain issues. Generally, aside from settling in, you should not expect issues, and PEP is only for 28 days.

Should you have some loose stool or nausea, do report it to your doctor, and you can find some general tips here: https://www.poz.com/basics/hiv-basics/nausea-vomiting-diarrhea

 Here's what you need to know to avoid HIV infection:
Use condoms for anal or vaginal intercourse correctly and consistently, with no exceptions. Consider talking to your healthcare provider about PrEP as an additional layer of protection against HIV

Keep in mind that some sexual practices described as safe in terms of acquiring HIV still pose a risk for other easier acquired STIs. So please do get tested at least yearly for STIs, including but not limited to HIV, and more frequently if condomless intercourse occurs.

Also, note that it is possible to have an STI and show no signs or symptoms, and the only way of knowing is by testing.

Kind regards

Jim

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HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline landersen

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Re: Truvuda PEP side effects
« Reply #2 on: September 07, 2022, 12:53:54 pm »
Thanks for the reply and thanks for moving my post (didn't realize where I was posting it).

I'm taking PEP because of a drunken encounter 48 hours ago where I was a receptive partner for a hookup and I was shitfaced (pardon my French) drunk.  When I woke up the next morning, the person I hooked up with was gone, there were no condoms to be found, and he blocked me on the app I was using.  I honestly don't remember much about the encounter suffice to say that when I woke up the next morning, something felt very off about the encounter.

Thank you for the info.  I did get a full panel of STI tests and am awaiting the results.

Offline landersen

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Re: Truvuda PEP side effects
« Reply #3 on: September 07, 2022, 12:56:34 pm »
Oh, and one more question.  Does anyone know if there are any concerns about taking Melatonin with Truvada and Inestress?  the melatonin really helps me fall asleep because of my Tinnitus.

Thanks.

Online Jim Allen

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Re: Truvuda PEP side effects
« Reply #4 on: September 07, 2022, 01:04:55 pm »
Thanks for the reply and thanks for moving my post (didn't realize where I was posting it).

I'm taking PEP because of a drunken encounter 48 hours ago where I was a receptive partner for a hookup and I was shitfaced (pardon my French) drunk.  When I woke up the next morning, the person I hooked up with was gone, there were no condoms to be found, and he blocked me on the app I was using.  I honestly don't remember much about the encounter suffice to say that when I woke up the next morning, something felt very off about the encounter.

Thank you for the info.  I did get a full panel of STI tests and am awaiting the results.

Well, prehaps after you have finished PEP & testing you could consider PrEP as an additional layer of HIV prevention going forward.

Anyhow, PEP is thankfully highly effective, test at six weeks post finishing PEP with a blood-draw (Lab) HIV antibodies test and a non-reactive result at that time would rarely ever change and retesting at three months post finishing PEP is generally not needed.


Oh, and one more question.  Does anyone know if there are any concerns about taking Melatonin with Truvada and Inestress?  the melatonin really helps me fall asleep because of my Tinnitus.

Thanks.


I don't know of any interaction between these drugs and Melatonin and neither is anything listed on drugs.com, however, always check with a qualified pharmacist.

https://www.drugs.com/interactions-check.php?drug_list=1548-0,971-1696,2413-12294



HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline landersen

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Re: Truvuda PEP side effects
« Reply #5 on: September 11, 2022, 01:01:50 pm »
On day 6 of Pep medications and have only had minor side effects (mild headache, a bit of nausea, tiredness).  Yay.

It took me a while to get my meds because it was actually hard to find a pharmacy near me that had the Isentress and I had crappy insurance issues to work out.  I was able to start the meds within the 72 hour window, but just barely.  But I am the paranoid type and I have all kinds of scenarios running through my head right now, so my question is.

Let's say that I was infected, and that the meds do not end up preventing me from becoming positive.  Do I need to worry about any kind of drug resistance that might occur between the time I stop taking pep medications and the time I start actual ongoing treatment? 

I'm assuming there would be a gap of time in between stopping pep, getting retested, getting Dr. apt to prepare for treatment, etc.  That gap, where I'm not taking HIV meds while working on the logistics, is what I'm worried about.  I'm the kind of person that obsesses over worst case scenarios and it drives me crazy.

Thanks.






 

Online Jim Allen

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Re: Truvuda PEP side effects
« Reply #6 on: September 11, 2022, 01:59:04 pm »
Quote
Do I need to worry about any kind of drug resistance that might occur between the time I stop taking pep medications and the time I start actual ongoing treatment?

The infection would not gain resistance because of taking PEP, no.

Stop stressing about issues you simply don't have. Take the PEP, test when due and in the meantime, live your life as normal.
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

 


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