POZ Community Forums

Main Forums => Living With HIV => Topic started by: manhattanman on August 08, 2006, 06:47:52 pm

Title: My First Blip : Update
Post by: manhattanman on August 08, 2006, 06:47:52 pm: About 6 weeks ago posted a quaetion about a blip from undetectable to 616.
Back to undetectable; but t-cells dropped from 452 to 415, no biggie.
Thanks to all who repsonded
Title: Re: My First Blip : Update
Post by: bobik on August 08, 2006, 06:48:45 pm: congrats about being undetectable again!

Coen
Title: Re: My First Blip : Update
Post by: blondbeauty on August 08, 2006, 08:00:40 pm: Thank God. Maybe it was a mistake from the lab...
Title: Re: My First Blip : Update
Post by: HIVworker on August 08, 2006, 09:09:50 pm: Sounds like a real blip to me and unlikely to be an incorrect lab result. If it was 10K or more and went back down to undetectable I would be inclined to agree.

R
Title: Re: My First Blip : Update
Post by: Eldon on August 08, 2006, 10:44:51 pm: Hello Manhattanman, it is Eldon. Sounds like a lab error to me also.
Title: Re: My First Blip : Update
Post by: Lisa on August 08, 2006, 10:45:13 pm: Hiya Manhattan,
I haven't seen you around very much. Nice to hear from you, blips aside.
I'm glad things are going pretty well for you.
Take care of yourelf. :-*
Title: Re: My First Blip : Update
Post by: HIVworker on August 08, 2006, 10:49:11 pm: Why is everything a lab error? Viral loads that go up and back down again are VERY common. They frequently occur in people who are 'undetectable'. If you monitor someone with >50 copies every other day you see blips like this. If you get measured when you have a blip you will see it.

R
Title: Re: My First Blip : Update
Post by: Life on August 08, 2006, 11:14:45 pm: I guess we can never be "blipless" ;)
Title: Re: My First Blip : Update
Post by: HIVworker on August 09, 2006, 04:38:24 pm: ;) I guess not. However, the data I have read indicates that blipping does NOT lead to an increase in HIV drug resistance but merely all part of that "We can't eradicate it" problem with HIV medication. BLIPS occur more in some people than others and are not linked to anything of significance. If anyone is interested, I can dig out the paper so you can read it and make your own conclusions.

R - who is still writing his GALT history for J220 et al.
Title: Re: My First Blip : Update
Post by: HIVworker on August 10, 2006, 12:31:00 am: The article I read was for subscription only, but I did find this useful summary given by the main author Dr Robert Siliciano, M.D., Ph.D at John Hopkins.

https://hopkinsnet.jhu.edu/servlet/page?_pageid=1850&_dad=portal30p&_schema=PORTAL30P (https://hopkinsnet.jhu.edu/servlet/page?_pageid=1850&_dad=portal30p&_schema=PORTAL30P)

I'll ask Dr Siliciano for further details as promised and will get back to you. As I said it is a normal phenomenon and nothing to be worried about. I'll check on what I can find about BLIPS that are higher than 200 virions that return to undetectable. My feeling is that given you had a variable viral load that bounces around undetectable it is mere fluctuation around an average that borders on the limits of detectability.

R