Welcome, Guest. Please login or register.
December 01, 2022, 03:50:01 pm

Login with username, password and session length

  • Total Posts: 766835
  • Total Topics: 65454
  • Online Today: 211
  • Online Ever: 5484
  • (June 18, 2021, 11:15:29 pm)
Users Online
Users: 1
Guests: 209
Total: 210


Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Do I Have HIV?” posting guidelines. Click here for posting guidelines pertaining to all other POZ community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Can HIV Treatment Be Taken Just 4 Days a Week? Studies are very promising  (Read 5625 times)

0 Members and 1 Guest are viewing this topic.

Offline bluedog7000

  • New Member
  • Posts: 2
Here's an article


I wonder if this can be done with the current medications or only the future ones. I wonder if anyone has tried that and if so with what medication?

Offline Jim Allen

  • Administrator
  • Member
  • Posts: 19,791
  • Twitter @JimAllenDublin
    • HIV Lessons

Welcome to the forum.

I know some people have, mixed results, study results seem promising though.

What medication are you taking and how are you getting on? Is four days a week something you are considering and if so have you discussed four days a week with your doctor?

There are a number of studies into four days a week and threads on them if you are looking for more information.

Caution over French study only taking ART 4 days a week

FOTO: https://www.poz.com/article/hiv-efavirenz-intermittent-16959-8019

Every Other Day: https://forums.poz.com/index.php?topic=72189.msg

Thread: Newer HIV Regimens May Require Less Strict Adherence

Thread: Fours days a week

« Last Edit: April 21, 2021, 11:46:24 am by Jim Allen »
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline bluedog7000

  • New Member
  • Posts: 2
I'm on Dovato now (from Biktarvy), supposedly it does less damage but not sure all about it.

Offline Matths

  • Member
  • Posts: 91
Hi there, based on what my doctor tells me and the existing literature I would not support an approach of experimenting with dosing despite some studies that might suggest otherwise. I am Dovato too and the reasoning behind this drug was to reduce the number of drugs in the single pill to reduce the overall exposure to medications over time and with doing that avoiding possible side effects that may come up with long-term exposure. But especially for the 2-drug combo pills the recommendation is to take them daily. I do not want to comment on other drugs but speak for Dovato only. As you can see on page 18/19, the half-life time for the 2 drugs in this combo is 14 hours for dolutegravir and 13-18 hours for lamivudine. That means that the drug concentration is reduced 50% at those time points after taking the pill. While missing a drug occasionally may not result in virological failure if itís a single event, doing it routinely may change that risk. Therefore, it makes most sense to not allow the drug concentration in your blood fall too low regularly and reach levels that donít control the virus. Clearly, my thinking is if I tolerate the medication well and it keeps me UD to take it regularly. And if I had side effects, Iíd rather switch medications to a regime that works rather than changing (reducing) the daily intake to any other schedule and thereby increasing my risk to end up with medication-resistant HIV. Best Matt

Offline nethan1621

  • Member
  • Posts: 48
Whos doing 4 days a week ?

Offline Giancarlo

  • Member
  • Posts: 30
I have been doing 4 days a week for about 3 years now.
I'm on Atripla, it is an "old" medication but it works well for me and is available as a generic drug, so all in all my treatment costs "only" about 140Ä per month to my country - and 0Ä to me :)

In France, it is stated in the official guidelines that such a strategy (4 days a week) can be considered, but case by case.
Nov 2011: HIV-
Jul 2012: HIV+
Aug 2012: VL 8,900 / CD4 822 (28%)
Oct 2012: VL 13,500 / CD4 887 (30%)
Jul 2013: VL 9,000 / CD4 ?
Sep 2013: VL 24,000 / CD4 625 (34%)
Oct 11th 2013: Start Atripla
Nov 7th 2013: VL 84 / CD4 665 (37%)
Dec 11th 2013: VL UD (<40) / CD4 960 (35%)


Terms of Membership for these forums

© 2022 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.