--- Quote from: Jim Allen on March 22, 2023, 04:34:50 am ---I see this case trending in the media. There is no update, although the full paper has been published, and it's an interesting read.
HIV-1 remission and possible cure in a woman after haplo-cord blood transplant https://www.cell.com/cell/fulltext/S0092-8674(23)00173-3
--- End quote ---
POZ.com article on this case: https://www.poz.com/article/mixedrace-woman-potentially-cured-hiv-using-stem-cell-transplant
Jim Allen:
Geneva case - HIV remission at 20 months after stem cell transplant for cancer treatment. Early days and continued monitoring, and further testing is needed.
--- Quote ---Known only as the Geneva Patient, a sixth person appears to have been cured of HIV after a stem cell transplant for cancer treatment, according to a case study presented at the International AIDS Society Conference on HIV Science (#IAS2023) in Brisbane, Australia.
The man received a transplant in July 2018 using so-called wild-type stem cells without the CCR5-delta32 mutation. He stopped antiretroviral treatment in November 2021 and has no evidence of HIV rebound or replicating virus 20 months later, Asier Sáez‐Cirión, PhD, of Institut Pasteur in Paris, and Alexandra Calmy, MD, PhD, of Geneva University Hospitals, reported at a preconference press briefing.
“All the immunological markers we have analyzed have been unable to detect HIV products,” Sáez‐Cirión said. “We cannot exclude that there is still some virus present…so there may be viral rebound in the future, although we hope this situation of viral remission remains permanent.” --- End quote ---
Jim Allen:
Nothing new really, another remission case. The abstracts will not be available until Monday so I'll have another look then.
--- Quote ---The anonymous 60-year-old man was diagnosed with HIV in 2009 and received a transplant to treat acute myeloid leukemia in October 2015. He stopped antiretroviral therapy in September 2018 and still has sustained HIV remission nearly six years later, Christian Gaebler, MD, of Charité University of Medicine in Berlin told reporters.
The apparent success of this procedure suggests that the stem cell donor pool could be expanded, giving more HIV-positive cancer patients a chance to be cured of HIV. The procedure is too risky for people who don’t have life-threatening malignancies, but each case offers new clues. --- End quote ---