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HIV Treatment reduces but doesn't stop HIVís acceleration of cell aging

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Jim Allen:
Very small sample size but still interesting, future studies needed.

Full POZ.com writeup: https://www.poz.com/article/antiretrovirals-stop-cell-aging

In short:


--- Quote ---People with untreated HIV in a recent study had signs of faster cell aging, which treatment reduced but did not eliminate.

Mary Sehl, MD, of the University of California, Los Angeles, and her colleagues extracted DNA from 15 people with HIV at three points: six to 12 months before they first began taking ARVs and six to 12 months and 18 to 24 months after they started HIV treatment.

The investigators analyzed what are known as cell epigenics, or factors that affect the expression of genes. Looking for key signs of cell aging in particular, they found that compared with a group of 15 age-matched HIV-negative individuals, people with HIV had signs of accelerated cell aging before they started ARVs. And while starting treatment reduced such cell aging, it did not totally eliminate it.
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