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Author Topic: Question about Adherence  (Read 2446 times)

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Offline Seigmeyer-of-Catarina

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  • Posts: 15
Question about Adherence
« on: April 15, 2021, 12:08:27 am »
Iím probably being too cautious, (or maybe not) but Iíve found myself taking my Biktarvy first thing in the morning at around 10:00. At least once or twice a week, Iíve taken it a little bit late by around 1-2 hours (3 hours once) depending on how late I sleep in. Anyway my question is whether or not this could potentially cause resistance? I still havenít miss a dosed but I wasnít sure if over time taking late doses could be problematic.

Offline Almost2late

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  • Posts: 1,426
Re: Question about Adherence
« Reply #1 on: April 15, 2021, 01:03:57 am »
I used to worry just like you the first couple of years, and I'm pretty sure I asked the same question on the forum when I was a newbie.
But I wouldn't sweat it, I've been doing the same thing and my vl has been consistently ud for the past few years.. I even have forgotten to take it a few times, and I really never take it at the exact same time in the morning. Sometimes 3 or 4 hours difference. Though I'm not suggesting you get as careless as I have.. just do your best like you have been.
Diagnosed - Feb.2014 Cd4 13, at 2.8%
Recent - Sept 2021 Cd4 284 at 17.8%

Offline leatherman

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Re: Question about Adherence
« Reply #2 on: April 15, 2021, 08:11:13 am »
while not all of my post applies to your situation, I recently made this post about resistance

TL;DR optimal adherence is 95% and missing doses (not late doses) haphazardly is what can cause resistance
leatherman (aka mIkIE)


  • Guest
Re: Question about Adherence
« Reply #3 on: April 17, 2021, 01:00:08 pm »
Current meds give you a pretty broad window (a few hours) so it's okay if this happens to you.

I used to take mine in the morning but because of that I then moved it to lunch time to make sure I don't oversleep past that safe window of time.

Offline Almost2late

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Re: Question about Adherence
« Reply #4 on: April 17, 2021, 02:07:16 pm »
TL;DR optimal adherence is 95%
Just wanted to point out that the very few times I've missed doses, I was well within this range.
Diagnosed - Feb.2014 Cd4 13, at 2.8%
Recent - Sept 2021 Cd4 284 at 17.8%

Offline Mojito

  • Member
  • Posts: 52
Re: Question about Adherence
« Reply #5 on: April 23, 2021, 06:29:17 am »
While modern medicines do have a broad window and few hours (1 - 2) difference on either side does not matter,it does help to set up a reminder on mobile phone.

Offline Isma95

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  • Posts: 12
Re: Question about Adherence
« Reply #6 on: April 24, 2021, 12:45:25 pm »
Iíve been HIV+ for two and a half years now, I always take my pill in the morning at around 8 but sometimes take it at 10 or even later in the weekend. Never missed a single dose but I sometimes take it late and my viral load stayed undetectable.
10/15/2018 - Tested HIV+
10/18/2018 - HIV+ Confirmed
10/22/2018 - VL 126,500; CD4 294 (15%); CD4/CD8 47%
11/06/2018 - VL 104,400; CD4 396 (18%); CD4/CD8 46%
-> Started treatment with Prezcobix+truvada
02/26/2019 - VL UD; CD4 675 (25%); CD4/CD8 81%
-> 04/09/2019 Switched to Tivicay+Lamivudine (now same meds in Dovato)
09/12/2019 - VL UD; CD4 966 (23%); CD4/CD8 89%
06/15/2020 - VL UD; CD4 1470 (30%); CD4/CD8 115%
04/12/2021 - VL UD; CD4 1182 (32%); CD4/CD8 145%


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