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Author Topic: Antibody works on 99% of Hiv strains  (Read 4504 times)

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Offline Almost2late

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Antibody works on 99% of Hiv strains
« on: September 22, 2017, 08:29:34 pm »
Reposting.. not sure who posted it originally but thanks for sharing..

This is indeed promising.. maybe a future vaccine or cure.. 

Quote
"We're getting 99% coverage, and getting coverage at very low concentrations of the antibody," said Dr Nabel.
Experiments on 24 monkeys showed none of those given the tri-specific antibody developed an infection when they were later injected with the virus.
Dr Nabel said: "It was quite an impressive degree of protection."...
read more..
http://www.bbc.com/news/health-41351159
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Offline paintedroom

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Re: Antibody works on 99% of Hiv strains
« Reply #1 on: September 23, 2017, 06:41:40 am »
I`m tempted to feel a teeny weeny bit excited but wiser voices usually show up at this time with contradictory evidence..so ě`ll wait..
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Offline Jim Allen

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Re: Antibody works on 99% of Hiv strains
« Reply #2 on: September 23, 2017, 08:18:20 am »
It's indeed interesting and a possible vaccine is exciting, not from any cure point of view but enhanced treatment and prevention sure.

However we have seen things look great in monkeys before flop in human real world tests. If I was a monkey I would be very excited though but I'm human so I will wait and see.

I tend to not get excited unless it's on a shelf and ready to be sold to me, every mouth it seems some has the next big hiv breakthrough very few of they yield results that result in a end product, but it does further our knowledge.

Jim
« Last Edit: September 23, 2017, 08:30:00 am by JimDublin »
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Offline Ptrk3

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Re: Antibody works on 99% of Hiv strains
« Reply #3 on: September 25, 2017, 06:48:28 pm »
Another story on the "trispecific" antibody from the September 25, 2017, edition of POZ online magazine:

https://www.poz.com/article/scientists-set-stage-combination-hivantibody-treatment-prevention

Link to the September 20, 2017, press release on the subject from the National Institute of Allergy and Infectious Diseases:

https://www.niaid.nih.gov/news-events/three-one-antibody-protects-monkeys-hiv-virus

From the press release:

Sanofi is manufacturing the trispecific antibody for use in a Phase 1 clinical trial that will be conducted by NIAID to test the antibody’s safety and pharmacokinetics in healthy people beginning in late 2018. Discussions also are under way with the NIAID-funded AIDS Clinical Trials Group to conduct a separate Phase 1 clinical trial of the antibody in people living with HIV.

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