Welcome, Guest. Please login or register.
May 29, 2024, 04:59:56 am

Login with username, password and session length


Members
Stats
  • Total Posts: 773606
  • Total Topics: 66391
  • Online Today: 266
  • Online Ever: 5484
  • (June 18, 2021, 11:15:29 pm)
Users Online
Users: 1
Guests: 216
Total: 217

Welcome


Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Do I Have HIV?” posting guidelines. Click here for posting guidelines pertaining to all other POZ community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: This is scary  (Read 3877 times)

0 Members and 1 Guest are viewing this topic.

Offline stuka

  • Member
  • Posts: 63
This is scary
« on: October 21, 2016, 12:38:19 pm »
So apparently, HIV is still finding a way to beat the latest advances in medicine ...

http://medicalxpress.com/news/2016-10-hiv-tissues-patients.html

I'm doing well on complera, and thought as long as I took the pills on time and stayed healthy, I'd live a normal lifespan. But after reading this report, it's like someone punched me in my guts.

What's the point of living a normal lifespan when the virus would cause other non-AIDS-related diseases like cancer, etc.

Offline Jim Allen

  • Administrator
  • Member
  • Posts: 22,507
  • Threads: @jim16309
    • Social Media: Threads
Re: This is scary
« Reply #1 on: October 21, 2016, 02:21:12 pm »
I will be honest this does not sound new to me at all, I will check tomorrow when I have more time to find a correct reference but HIV levels in tissue is not a new fact at all. Its also nothing to stress about.

Jim
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

My Instagram
Threads

Offline Ptrk3

  • Global Moderator
  • Member
  • Posts: 2,792
Re: This is scary
« Reply #2 on: October 21, 2016, 02:25:31 pm »
There's no reason to believe you won't live a normal lifespan because of this single, isolated study.  The operate verb throughout is "may" and "could," so even if the study is true, that does not mean that any particular individual will develop any specific non-aids-related disease.  Other studies may draw different conclusions.

However, it may help you to determine with your doctor how to look out especially for any preliminary signs of all non-aids-related diseases ( a regular colonoscopy, an annual heart examination, etc.) and/or take particular precautions in your daily life (such as diet and exercise, for example).  That type of scrutiny can add years to an individual life, whether or not one is infected by the HIV.

In the meantime, keep doing well on your Complera and continue to live a long and healthy life.

HIV 101 - Basics
HIV 101
You can read more about Transmission and Risks here:
HIV Transmission and Risks
You can read more about Testing here:
HIV Testing
You can read more about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read more about HIV prevention here:
HIV prevention
You can read more about PEP and PrEP here
PEP and PrEP

Offline Jim Allen

  • Administrator
  • Member
  • Posts: 22,507
  • Threads: @jim16309
    • Social Media: Threads
Re: This is scary
« Reply #3 on: October 21, 2016, 02:48:58 pm »
Yeah, so this is the same stuff i read a few month back. http://jvi.asm.org/content/90/20/8968

I am not seeing any concern, we already knew about HIV reservoirs, this changes nothing it just help us understand them slightly better. HIV infecting macrophages was also already well known.*

*
https://retrovirology.biomedcentral.com/articles/10.1186/1742-4690-9-82

Jim
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

My Instagram
Threads

Offline mecch

  • Member
  • Posts: 13,455
  • red pill? or blue pill?
Re: This is scary
« Reply #4 on: October 21, 2016, 03:43:34 pm »
What's the point of living a normal lifespan when the virus would cause other non-AIDS-related diseases like cancer, etc.

Nobody promised me a rose garden - that HIV infection was harmless, despite the very optimistic and reassuring words from my specialist that treatment would allow me to work and live my life normally. Treatment has done that. 

Were you expecting that ALL issues related to HIV infection were "cured" by treatment?

Please put things in perspective.  Before today's treatment, HIV was a horror show.  Nothing by sickness, suffering, pain and death.

“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline mecch

  • Member
  • Posts: 13,455
  • red pill? or blue pill?
Re: This is scary
« Reply #5 on: October 21, 2016, 03:50:19 pm »
Just wanted to add that, semantically, if HIV in tissues is causing cancers or cardio-vascular disease, it IS HIV-related disease.  I don't think I will ever had AIDS.  Really I don't.  But if I go from a cancer linked to HIV, that wouldn't shock me.
Cancers are related to HPV, too.  And I got that, too.  Something is going to get me, probably before 90, like a few members of my family do reach.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline CaveyUK

  • Global Moderator
  • Member
  • Posts: 1,642
Re: This is scary
« Reply #6 on: October 21, 2016, 03:57:26 pm »
Yep, when I read one of these new batch of articles the other day my heart stopped for a second, but then I realised there was nothing new.

All it's saying is that the meds we take do not touch the viral reservoirs, which we already knew.

However, it doesn't affect transmission risks as the undetectable levels of virus in the blood (and semen) take care of that.

What it does do, is mean that there is a resultant issue of low level inflammation, which again we knew about. And that this can lead to certain issues with age-related disorders in 'some' people as they age - most of which can be treated of course. Again, nothing new, and something that many of us hope the latest research will target.

Another point....all the specimens tested came from people who already had cancer, but there any many many folks living with HIV into old age who do not have cancer.

Interestingly, there is a terminology error in this report too. It states that :

Quote
The research team found evolving "wild type" HIV, that is virus unaffected by antiretroviral therapy, in the cerebellum, lymph nodes, lungs, colons, and spleens amongst others tissues.

'Wild-Type' HIV does not mean it is unaffected by antiretroviral therapy, it means it is susceptible to all antiretroviral therapy. Perhaps it is just a clumsy use of the word when they mean the same thing. But someone on effective ART can have 'wild type' HIV determined through genotyping - in fact, most people do.

If someone starts with any resistant strain of HIV, then regardless of what happens with ART, their bodies will not reverse-engineer the viral strain to be 'wild type'.

Thats my understanding anyway :)
HIV - Basics
HIV 101
You can read more about Transmission and Risks here:
HIV Transmission and Risks
You can read more about Testing here:
HIV Testing
You can read more about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read more about HIV prevention here:
HIV prevention
You can read more about PEP and PrEP here:
PEP and PrEP

Offline CaveyUK

  • Global Moderator
  • Member
  • Posts: 1,642
Re: This is scary
« Reply #7 on: October 21, 2016, 04:12:26 pm »
Just wanted to add that, semantically, if HIV in tissues is causing cancers or cardio-vascular disease, it IS HIV-related disease.  I don't think I will ever had AIDS.  Really I don't.  But if I go from a cancer linked to HIV, that wouldn't shock me.
Cancers are related to HPV, too.  And I got that, too.  Something is going to get me, probably before 90, like a few members of my family do reach.

Unless it's a cancer known to be specific/unique to HIV, you'd probably never know whether it was truly related as cancers can be 'caused' or influenced by a variety of factors, some just genetic. Ditto with cardiovascular disease....for me personally, if I had cardiovascular disease then it *could* be HIV related, or could be the years of mistreatment I dealt my body through terrible diet and lack of exercise!

You are quite right of course, that the situation not very long ago was very bleak for people living with this virus, and in most cases meant a horrible death of AIDS. These days, with modern meds, we can live long lives with few - if any - side-effects and in most cases will die of something boringly mundane, just like everyone else.

Very many people would have swapped their mid-80's prognosis with the prospect of treatable cardiovascular or cancer risks in later life, in a heartbeat.
HIV - Basics
HIV 101
You can read more about Transmission and Risks here:
HIV Transmission and Risks
You can read more about Testing here:
HIV Testing
You can read more about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read more about HIV prevention here:
HIV prevention
You can read more about PEP and PrEP here:
PEP and PrEP

Offline harleymc

  • Member
  • Posts: 1,528
Re: This is scary
« Reply #8 on: October 21, 2016, 05:21:32 pm »
So you're scared because HIV treatment is not preventative for cancer? Then start acting like you are going to live a long time and start reducing your cancer risk factors.

ART has never been marketed as a cancer prevention strategy.

Offline Tonny2

  • Member
  • Posts: 3,021
Re: This is scary
« Reply #9 on: October 21, 2016, 09:41:30 pm »

        :) :D 8)    HELLO MY FRIEND HOW NICE TO HEAR FROM YOU AGAIN, WELCOME HOME AGAIN.

ALMOST 22 YEARS AGO, THE DOCTOR TOLD ME THAT I WOULD LIVE ONLY TWO MORE YEARS, I SAID TO MYSELF, WE''LL SEE, EVEN WHEN I LIVED WITH AIDS FOR FIVE YEARS BECAUSE OF TREATMENT FAILURE, I STILL TOOK THE MEDS, EVEN THOUGH I KNEW THEY WERE NOT WORKING, JUST CAUSING ME MORE PROBLEMS (NEUROPATHY), AND, I'M STILL HERE, WRITING TO YOU, PLEASE, LIVE YOUR PRESENT, IT'S THE ONLY THING WE HAVE, OUR LIVES IN PRESENT TIME, ENJOY YOUR FAMILY, FRIENDS, LIFE ITSELF, DO NOT WORRY UNTIL YOU HAVE SOMETHING TO WORRY ABOUT...CAN YOU IMAGINE WHAT WOULD HAVE HAPPENED TO ME IF I WOULD HAVE STOPPED LIVING MY THEN PRESENT AND THINK ABOUT MY FUTURE?, I WOULDN'T BE HERE, I ALWAYS HAD FAITH, I'M NOT A RELIGIOUS GUY, BUT I'VE ALWAYS SEE THINGS ON THE BRIGHT SIDE, EVEN THOUGH I'M BECOMING A BLIND GUY, LOL, STILL "SEE THE LIGHT AFTER THE TUNNEL"...gIN migo, enjoy the present, it's the only thing we have for sure, live everyday as it was your last one...just a thought  ojo

ps, again, so nice to have you back on here...hugs
« Last Edit: October 22, 2016, 07:13:34 pm by JimDublin »

 


Terms of Membership for these forums
 

© 2024 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.