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Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

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Recent Posts

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81

Aidsmap article in full:
https://www.aidsmap.com/news/may-2024/i-felt-i-was-dirty-experiences-gay-men-diagnosed-mpox-england

In Brief:

Quote
A recent study found that men diagnosed with mpox, clinicians and community stakeholders believe that the government's perceived inaction towards the illness was due to its association with stigmatised sexual minorities. This systemic failure was often compared to the initial response to the AIDS crisis.

With the exception of an Australian study, there has been limited qualitative research on the patient experience of mpox. To better understand the social and clinical support needs of people with mpox, researchers from University College London conducted interviews with 22 gay and bisexual men who were diagnosed with monkeypox in England in 2022. The researchers who conducted the interviews were also cisgender gay men.

During the 2022 outbreak, HIV-negative gay and bisexual men who had little experience with stigmatising illnesses found their mpox diagnosis to be particularly traumatic and a personally threatening experience. They often required additional support beyond what was available. However, men living with HIV seemed to handle the stigma better, drawing on resilience from past experiences with HIV.

Mpox was associated with significant feelings of stigma, particularly due to homophobic narratives that linked promiscuity with illness and disease. Some men were also discriminated against by sexual contacts, online, and in healthcare settings. All men who had contact with non-specialist hospital services (such as Accident and Emergency) after receiving an mpox diagnosis reported some degree of enacted stigma from staff, usually related to infection control measures.

Conclusion
The lack of cultural competence in some health services that catered to gay and bisexual men resulted in stigmatisation and, at times, distress. This highlights the importance of involving members of affected communities in co-producing, planning and delivering care – including contact tracing, where stigma is likely to be a significant barrier to engagement.

“This should be done continuously from the outset of outbreaks and be accompanied by appropriate funding, especially for community-based organisations who often face financial precarity,” the authors conclude.


82
Research News & Studies / Re: EBT-101
« Last post by Jim Allen on May 13, 2024, 11:56:49 am »
I have not seen all the details yet, but if correct it's a flop in terms of an HIV cure, even the one patient out of five reaching 16 weeks is nothing to praise with standard modern ART. *

Excision’s CRISPR-Based HIV Treatment Fails to Show Curative Potential in Early Study

https://www.biospace.com/article/excision-s-crispr-based-hiv-treatment-fails-to-show-curative-potential-in-early-study-/

Quote
Excision BioTherapeutics’ attempt to use a CRISPR-based gene editing therapy to cure HIV has failed an early-stage study, according to several media reports on Friday.

Results from the Phase I trial of five patients showed that Excision’s CRISPR therapeutic did not strongly suppress the HIV virus. Three patients who were taken off of antiretroviral therapy soon developed viral rebound and needed to resume conventional treatments, according to reporting by STAT News.

Still, Excision’s approach did show signs of promise. One patient was able to keep the virus at bay for 16 weeks after stopping antiretroviral treatment before rebounding.

I'll keep my eyes open for more details when they become available and post them here.



* HIV Time to Viral Rebound After Interruption of Modern ART.
https://forums.poz.com/index.php?topic=76642.msg
83
Forums Gatherings / Re: Biweekly Peer Support Call
« Last post by Jim Allen on May 13, 2024, 11:11:06 am »
It’s always so great to connect with others on here, but sadly I’ve lost sight of what I wanted for these meetings. I think perhaps our mission and numbers would be stronger under someone else’s guidance. There is value in a clinical discussion from a shared perspective. Likewise, community and fellowship are vital to maintaining a positive future outlook. I hope everyone here finds that great future- be it from our one time posters, to the lurkers who read only, or to the few regulars who actively participate to make this space so wonderful.

I'm sorry to hear this and want to thank you for the leadership & care you put into this and thanks to everyone who worked to support these calls.

I feel we still need a separate call dedicated to Peer support and HIV updates (News) but it is something I will get back to you and the others on at a later date.

Quote
I look forward to connecting with everyone on the monthly virtual gatherings. If you aren’t participating in those, they are great fun.

 :) Absolutely, the monthly calls certainly are fun and a nice way to connect and catch up with each other.
https://forums.poz.com/index.php?topic=77368.0

84
Forums Gatherings / Re: Biweekly Peer Support Call
« Last post by numbersguy82 on May 13, 2024, 09:41:26 am »
It’s always so great to connect with others on here, but sadly I’ve lost sight of what I wanted for these meetings. I think perhaps our mission and numbers would be stronger under someone else’s guidance. There is value in a clinical discussion from a shared perspective. Likewise, community and fellowship are vital to maintaining a positive future outlook. I hope everyone here finds that great future- be it from our one time posters, to the lurkers who read only, or to the few regulars who actively participate to make this space so wonderful.


I look forward to connecting with everyone on the monthly virtual gatherings. If you aren’t participating in those, they are great fun.
85
Do I Have HIV? / Re: Unsure
« Last post by Jim Allen on May 13, 2024, 04:14:10 am »
Asked and answered.

You didn't have an HIV risk from this encounter, move on with your life.

[Note: I merged the two threads]
86
Do I Have HIV? / Re: Unsure
« Last post by Mistaker on May 13, 2024, 04:06:00 am »
Hi Jim. I had sex that lasted two minutes. After the sex, I really inspected the condom to be sure that it didn't break. It didn't break and I was sure it didn't break. Dunno if a condom can break secretly. But how much risk am I in if it broke? Her hole was so hot
87
Do I Have HIV? / Re: Unsure
« Last post by Jim Allen on May 13, 2024, 03:04:07 am »
Hiya.

You had sex and used condoms, it's not an HIV concern.

HIV can't be transmitted through an intact latex, polyisoprene or polyurethane condom. Unless a condom obviously fails during intercourse, there is no reason to be stressing about HIV or testing for HIV outside the standard yearly HIV screening.

Quote
how much risk am I in if it broke?

"If" the condom had broken during intercourse it would have been obvious and a potential HIV risk, but that didn't happen, so relax and move on with your life.



Here's what you need to know to reduce your HIV risks:
Use condoms for anal or vaginal intercourse correctly and consistently, with no exceptions. Consider talking to your healthcare provider about PrEP as an additional layer of protection against HIV and get vaccinated against HPV, Hepatitis A & B.

Keep in mind that some sexual practices described as safe in terms of acquiring HIV still pose a risk for other easier-acquired STIs. So please do get tested at least yearly for STIs, including but not limited to HIV, and more frequently if condomless intercourse occurs.

Also, note that it is possible to have an STI and show no signs or symptoms; testing is the only way to know.

Kind regards

Jim

Please Note.
As a member of the "Do I have HIV" Forum, you are required to only post in this one thread no matter how long between visits or the subject matter. You can find this thread by going to your profile and selecting show own post, which will take you here. It helps us to help you when you keep all your thoughts or questions in one thread, and it helps other readers to follow the discussion. Any additional threads will be removed.
 
88
Do I Have HIV? / Unsure
« Last post by Mistaker on May 13, 2024, 02:37:57 am »
Hi Allen. I had sex that lasted two meanings. After the sex, I really inspected the condom to be sure that it didn't break. It didn't break and I was sure. But how much risk am I in if it broke? Didn't find the place to post my own question
89
Do I Have HIV? / Re: On demand-prep and VERY HIGH risk exposure
« Last post by Jim Allen on May 12, 2024, 09:56:48 am »
Hiya,

I read your post three times, what this person did might be a criminal offence in some jurisdictions and I am sorry to hear this happened to you.

In brief, there was condomless intercourse but you are taking PrEP On-demand and started 4 hours before sex. On-demand (event-based PrEP) is highly effective and the initial double dose should be between 24 and 2 hours before sex. https://i-base.info/guides/prep/real-life-examples-for-on-demand-dosing

Their test results are meaningless to you due to the window period and for several other reasons and puking the next day will not change PrEPs effectiveness.

Anyhow, I read what you posted here and I see no reason for any HIV stress or testing outside of routine, as you are using PrEP ideally you should get an HIV & STI screening every three months.



Here's what you need to know to reduce your HIV risks:
Use condoms for anal or vaginal intercourse correctly and consistently, with no exceptions. Continue to use PrEP as an additional layer of protection against HIV and get vaccinated against HPV, Hepatitis A & B.

Keep in mind that some sexual practices described as safe in terms of acquiring HIV still pose a risk for other easier-acquired STIs. So please get tested routinely, ideally every three months as a PrEP user.

Also, note that it is possible to have an STI and show no signs or symptoms; testing is the only way to know.

Kind regards

Jim

Please Note.
As a member of the "Do I have HIV" Forum, you are required to only post in this one thread no matter how long between visits or the subject matter. You can find this thread by going to your profile and selecting show own post, which will take you here. It helps us to help you when you keep all your thoughts or questions in one thread, and it helps other readers to follow the discussion. Any additional threads will be removed.


90
Do I Have HIV? / On demand-prep and VERY HIGH risk exposure
« Last post by huangDi on May 12, 2024, 09:37:43 am »
Greetings to everyone, I want to express my thankfulness for the perseverance of the mods of this wonderful online community. I am quite distressed as i had a sexual exposure of very high risk just 2 days ago.

I recently learned about on-demand prep and given my infrequent hookups and my need to have an extra layer of protection, I decided this is a solution that could work for me without having to worry about daily adherence. So i decided to engage in receptive anal sex with a partner on Friday night and 4 hours earlier I took the 2 pills of PreP (Tenofovir Disoproxil Fumarate & Emtricitabine 300/200 mg). 4 hours after the two pills were taken, I met with the person and we had anal sex. I saw him opening the condoms box while i laid my back on him and made love. A few minutes later we stopped and I realized in great HORROR that HE WAS NOT WEARING A CONDOM. I got really upset about it and he apologized by saying he gets tested regularly and does not usually do that. He even showed me the results of a 4th generation HIV negative test he took about 20 days ago...This, combined with me being on On-demand PreP helped me alleviate most of the anxiety I am going through.

Now the problem is, if he was infected recently enough for the 4th generation NOT being able to pick the infection up, his viral load during this may be sky-rocket high and I am really afraid as I engaged in the riskiest sexual behaviour (unprotected receptive anal sex) + the fact that I took the 2 pills only 4 hours before the exposure and not the "ideal" 24 hours for on demand prep. The double dosage also gave me some sort of stomachache the next morning and I threw up. I adhered faithfully to the on-demand pill scheduling and I popped another pill 24 hours after the first double dosage, and I'm planning to pop the last one today.

Do you think Prep will protect me despite all the misfortunes of this encounter ?
Do you think throwing up the next morning could limit the effect of PreP consumed the previous evening ?
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