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Author Topic: Doing well on Atripla, but ready to swap out the Sustiva for....  (Read 3454 times)

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Offline NY2011

  • Member
  • Posts: 173
Doing well on Atripla, but ready to swap out the Sustiva for....
« on: September 14, 2013, 09:03:05 pm »
...Isentress?  As I mentioned in the title, my labs are excellent. I feel healthy. I play sports, travel a lot, and keep active. Sickness and health issues are just not a part of my life, thankfully, but I think that the Sustiva component in Atripla is contributing to some irregular sleep patterns for me.  My doctor continues to suggest Stribild, but being that I'm doing well on three drugs, switching to a four-drug regimen doesnt seem like the best solution.  It seems unnecessarily taxing on the body. So, just wondering if anyone else has been in a similar situation, and has found a great alternative to Sustiva. btw, I'm aware that I'd have to take Isentress twice a day. Thanks.
10/26/2011 - SEROCONVERSION (fever+rash, 104 degrees F)
10/31/2011 - CD4= 154  VL>500,000 
10/31/2011 - started on Truvada+Prezista+Norvir
12/14/2011 - CD4= 750 VL=6412 (45%)
01/27/2012 - switched to Atripla
04/23/2012 - CD4=1,221 VL= 140  (47%)
06/22/2012 - CD4=1,224 VL= ud    (49%)
12/18/2012 - CD4=1,031 VL= ud    (51%)
09/16/2013 - CD4=1,151 VL= ud   (49%)
03/26/2014 - CD4=1,050 VL= ud
11/25/2014 - CD4=1,335 VL= ud
12/01/2015 - CD4=1,115 VL= ud (55%)
11/22/2016 - CD4=1,071 VL= ud (52%)
06/01/2017 - CD4=1,014 VL= ud (53%)
switched to Biktarvy in 2018
04/23/2019 - CD4=1,072 VL= ud (52%)
01/15/2020 - CD4=  925  VL= ud (50%)

Offline buginme2

  • Member
  • Posts: 3,426
Re: Doing well on Atripla, but ready to swap out the Sustiva for....
« Reply #1 on: September 15, 2013, 05:41:48 pm »
I swapped out Atripla for Complera.  Was super easy and still one pill a day. 
Don't be fancy, just get dancey

Offline Piscean

  • Member
  • Posts: 43
Re: Doing well on Atripla, but ready to swap out the Sustiva for....
« Reply #2 on: September 15, 2013, 08:14:53 pm »
I made the switch from Atripla to Stribild for the same sleep related reasons. All labs are normal no sign of the fourth drug causing any issues. I couldn't be happier with this change. I wish I had listened to my Dr. and made the switch sooner. Of course YMMV.

Best of luck for whichever direction you go.


Offline mitch777

  • Member
  • Posts: 4,087
Re: Doing well on Atripla, but ready to swap out the Sustiva for....
« Reply #3 on: September 15, 2013, 08:33:09 pm »
Hi NY,

I was thrilled when I switched to truvada and isentress but I never had a sleep issue until the switch. need to take trazodone to sleep now. more people have sleep issues with atripla than isentress but it worked the opposite with me. not sure what advice to give you. the trade off was worth the change for cognitive issues for me but everyones side effects are so different.
it might work out well for you.
best wishes.

m.
33 years hiv+ with a curtsy.

Offline NY2011

  • Member
  • Posts: 173
Re: Doing well on Atripla, but ready to swap out the Sustiva for....
« Reply #4 on: September 17, 2013, 06:39:21 am »
Thank you for the feedback. Have any of you noticed a difference in your lab results?  Higher/lower CD4 as a result?

« Last Edit: September 17, 2013, 06:41:30 am by NY2011 »
10/26/2011 - SEROCONVERSION (fever+rash, 104 degrees F)
10/31/2011 - CD4= 154  VL>500,000 
10/31/2011 - started on Truvada+Prezista+Norvir
12/14/2011 - CD4= 750 VL=6412 (45%)
01/27/2012 - switched to Atripla
04/23/2012 - CD4=1,221 VL= 140  (47%)
06/22/2012 - CD4=1,224 VL= ud    (49%)
12/18/2012 - CD4=1,031 VL= ud    (51%)
09/16/2013 - CD4=1,151 VL= ud   (49%)
03/26/2014 - CD4=1,050 VL= ud
11/25/2014 - CD4=1,335 VL= ud
12/01/2015 - CD4=1,115 VL= ud (55%)
11/22/2016 - CD4=1,071 VL= ud (52%)
06/01/2017 - CD4=1,014 VL= ud (53%)
switched to Biktarvy in 2018
04/23/2019 - CD4=1,072 VL= ud (52%)
01/15/2020 - CD4=  925  VL= ud (50%)

Offline Miss Philicia

  • Member
  • Posts: 24,793
  • celebrity poster, faker & poser
Re: Doing well on Atripla, but ready to swap out the Sustiva for....
« Reply #5 on: September 17, 2013, 10:31:37 am »
When I switched to Isentress many years ago I indeed had a decent rise in my cd4 count, as well as my %. But I didn't switch from Atripla to this it was something else so not sure how much you can draw from that.
"I’ve slept with enough men to know that I’m not gay"

Offline Piscean

  • Member
  • Posts: 43
Re: Doing well on Atripla, but ready to swap out the Sustiva for....
« Reply #6 on: September 17, 2013, 08:37:37 pm »
Thank you for the feedback. Have any of you noticed a difference in your lab results?  Higher/lower CD4 as a result?

At four months on Stribild I had a 1% increase in my CD4%. Roughly a 150 increase in CD4's. I hope for continued progress when I have my labs run again next month.

But to your issue, my sleep has dramatically improved, both in quantity and quality.

Please keep us posted on your decision and how it works out for you.

Offline NY2011

  • Member
  • Posts: 173
Re: Doing well on Atripla, but ready to swap out the Sustiva for....
« Reply #7 on: September 20, 2013, 04:43:35 pm »
wow Mitch, 30 years. That is great news, with or without sleep issues. 
10/26/2011 - SEROCONVERSION (fever+rash, 104 degrees F)
10/31/2011 - CD4= 154  VL>500,000 
10/31/2011 - started on Truvada+Prezista+Norvir
12/14/2011 - CD4= 750 VL=6412 (45%)
01/27/2012 - switched to Atripla
04/23/2012 - CD4=1,221 VL= 140  (47%)
06/22/2012 - CD4=1,224 VL= ud    (49%)
12/18/2012 - CD4=1,031 VL= ud    (51%)
09/16/2013 - CD4=1,151 VL= ud   (49%)
03/26/2014 - CD4=1,050 VL= ud
11/25/2014 - CD4=1,335 VL= ud
12/01/2015 - CD4=1,115 VL= ud (55%)
11/22/2016 - CD4=1,071 VL= ud (52%)
06/01/2017 - CD4=1,014 VL= ud (53%)
switched to Biktarvy in 2018
04/23/2019 - CD4=1,072 VL= ud (52%)
01/15/2020 - CD4=  925  VL= ud (50%)

 


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