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Author Topic: in your opinion do the meds age your face?  (Read 21112 times)

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Offline surf18

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in your opinion do the meds age your face?
« on: July 10, 2011, 07:20:45 pm »
i am curious as to your opinion.... do you feel that the newer meds cause the face to age in apperance?
ive been on meds for a year ,im 41 and when i compare a pic from  a year ago to now i feel i aged 10 years. could just be me being a psycho but i was curious to others thoughts on this subject. im on selzentry /truvada.
thanks

Offline eric48

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Re: in your opinion do the meds age your face?
« Reply #1 on: July 10, 2011, 08:18:32 pm »
I have the same question in the back of my mind for several months know, and, unfortunately I think that my answer to your question is YES.

On the good news, I think that I am slowly recovering and getting a bit more energetic.

But that seems to be a slow process (I'm almost 50...)

Cheers!

Eric
NVP/ABC/3TC/... UD ; CD4 > 900; CD4/CD8 ~ 1.5   stock : 6 months (2013: FOTO= 5d. ON 2d. OFF ; 2014: Clin. Trial NCT02157311 = 4days ON, 3days OFF ; 2015: https://clinicaltrials.gov/ct2/show/NCT02157311 ; 2016: use of granted patent US9101633, 3 days ON, 4days OFF; 2017: added TDF, so NVP/TDF/ABC/3TC, once weekly

Offline buginme2

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Re: in your opinion do the meds age your face?
« Reply #2 on: July 10, 2011, 08:22:23 pm »
i am curious as to your opinion.... do you feel that the newer meds cause the face to age in appearance?
ive been on meds for a year ,im 41 and when i compare a pic from  a year ago to now i feel i aged 10 years. could just be me being a psycho but i was curious to others thoughts on this subject. im on selzentry /truvada.
thanks

Everything I have read attributes lipo issues to older nrtis (azt,etc) and some older pi's.  I have not read anything that states these issues occur with newer meds such as yours (truvada, selzentry).  Does that mean anything? I dunno.  I do know the insert that comes with Atripla states it can cause lipo issues and that section is written in all caps.  Maybe they are just putting that in the insert to stave off lawsuits.  

It seems weird though that you could be experiencing issues after only one year.  

Oh I should ask,  I'm just assuming you mean lipo issues on your face, what do you mean by "aging?". Do you mean fat loss in your face or wrinkles or what?   What exactly are you experiencing?
Don't be fancy, just get dancey

Offline surf18

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Re: in your opinion do the meds age your face?
« Reply #3 on: July 10, 2011, 08:28:48 pm »
thanks guys for the replies. i guess i mean more not so much facial wasting ,just look busted up weathered old now.
thats what im seeing in the mirror and in picture comparisons from one year ago to today.
could be my crazy mind or could be reality .........

Offline buginme2

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Re: in your opinion do the meds age your face?
« Reply #4 on: July 10, 2011, 08:45:01 pm »
Have you tried a good moisutrizer.  I swear by Kinerase pro+ therapy cream.  It works like magic.  :-)
Don't be fancy, just get dancey

Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #5 on: July 10, 2011, 09:09:47 pm »
Once you hit 40, regardless of HIV, you start looking haggard (unless you're George Clooney). Did you see Brad Pitt in Tree of Life yet? Poor thing is looking a bit bloated.

ps: try being on meds for two decades and I'll show you haggard from meds -- one year, I can't imagine it doing anything.
"I’ve slept with enough men to know that I’m not gay"

Offline next2u

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Re: in your opinion do the meds age your face?
« Reply #6 on: July 10, 2011, 09:17:13 pm »
i can't afford kinarse. i can barely afford my $20 clinique moisturizer. i get most of my stuff from target. i splurge a little and get moisture from clinique/aveda.

i am looking forward to the days when i can use kinarse. interestingly enough, when i was reading this article an ad from kinarse was on the left side of the screen~

best,
d
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Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #7 on: July 10, 2011, 09:22:50 pm »
Another thing to consider, when you're very stressed, depressed, and full of anxiety this will definitely effect your appearance.
"I’ve slept with enough men to know that I’m not gay"

Offline buginme2

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Re: in your opinion do the meds age your face?
« Reply #8 on: July 10, 2011, 09:49:00 pm »
i can't afford kinarse. i can barely afford my $20 clinique moisturizer. i get most of my stuff from target. i splurge a little and get moisture from clinique/aveda.

i am looking forward to the days when i can use kinarse. interestingly enough, when i was reading this article an ad from kinarse was on the left side of the screen~

best,
d

You can usually find some good deals online.  I got a 16oz bottle of kinerase cream from i beleive "skinstoreonline" for $100. (its usually 500 for that size) and its lasted me a year.  You dont need as much as clinique so even though its more expensive it last longer. 

I have also had IPL at my dermatologist.  I swear by that too.  If you can swing it, I recommend.  Totally smooths out your skin, evens tone, and gets rid of wrinkles.

Renova (perscription only) works too but it can be rough.
Don't be fancy, just get dancey

Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #9 on: July 10, 2011, 10:27:30 pm »
Just don't lay out by the pool in that hot sun year after year or you'll end up looking like an old piece of leather.
"I’ve slept with enough men to know that I’m not gay"

Offline Ann

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Re: in your opinion do the meds age your face?
« Reply #10 on: July 10, 2011, 10:42:50 pm »
Who cares what you look like. Be thankful you're alive and will be for years to come.

Condoms are a girl's best friend

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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

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HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #11 on: July 10, 2011, 11:08:16 pm »
Who cares what you look like. Be thankful you're alive and will be for years to come.



Jesus hates sloth.

ps: I just had a large brownie with whipped cream, and a cigarette
"I’ve slept with enough men to know that I’m not gay"

Offline surf18

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Re: in your opinion do the meds age your face?
« Reply #12 on: July 11, 2011, 07:26:24 am »
oh ann! im so damn vain!!!!!!! i care!!!
and miss p brought us a good point. i am proably all the above angry,pissed,deprressed,stressed and that proably has more effect than i thought.......

Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #13 on: July 11, 2011, 07:56:17 am »
oh ann! im so damn vain!!!!!!! i care!!!
and miss p brought us a good point. i am proably all the above angry,pissed,deprressed,stressed and that proably has more effect than i thought.......

Honey, you need a spa day -- spend the money and get a massage, facial, and a manicure.
"I’ve slept with enough men to know that I’m not gay"

Offline surf18

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Re: in your opinion do the meds age your face?
« Reply #14 on: July 11, 2011, 08:07:10 am »
ha sounds like a plan miss p. you come with me??

Offline mecch

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Re: in your opinion do the meds age your face?
« Reply #15 on: July 11, 2011, 08:09:09 am »
First, my personal experience.

On the "new" meds since Summer 2008, just a few months after seroconversion.  
Have not noticed anything special about my face "aging".  Nobody else has either. Im in my late 40s.

So generalized hunch:   Heck my face looks my age, but it still looks nice enough.  Im not a spring chicken.

The only time I was shocked about aging in my face was in my early thirties when I didn't look like a "young man" anymore.  Get OVER it was my self advice.  Don't live in the past, a fake youth, or a delusion, is my motto.  One time I dated a much older man and he finally could NOT get over aging and his self preception, and had all sorts of unfortunate plastic surgery.

Personally, I highly doubt that the "new" drugs cause 10 years of facial aging in one year.  

As others suggest, maybe stress, depression or being run down can effect your appearance.  Can also effect your perception of your appearance.  The latter is the KEY idea to think about.

I do know that living with AIDS can mark a face.   Therefore, being rather an optimist, and thankful for whats good, I just thank my lucky stars for this HAART 'cause my time of living with active HIV was quite limited.

  





“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline wolfter

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Re: in your opinion do the meds age your face?
« Reply #16 on: July 11, 2011, 08:21:16 am »
I dealt with this a while back and was sure I was aging worse than my contemporaries.  All it took was a class reunion to have a comparison.  Only then did I realize I'm aging pretty nicely! ;)
Being honest is not wronging others, continuing the dishonesty is.

Offline Billy B

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Re: in your opinion do the meds age your face?
« Reply #17 on: July 11, 2011, 11:26:45 am »
oh ann! im so damn vain!!!!!!! i care!!!
and miss p brought us a good point. i am proably all the above angry,pissed,deprressed,stressed and that proably has more effect than i thought.......

Surf- Are you drinking enough water? Something as simple as dehydration will make you look older.
Billy
VL 4420 CD4 340 CD4% 24   3/15/10 Started I&T
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Offline james3000

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Re: in your opinion do the meds age your face?
« Reply #18 on: July 11, 2011, 12:47:16 pm »
There is a very good website called science daily they had an article about this

http://www.sciencedaily.com/releases/2011/06/110626145257.htm 

www.sciencedaily.com look under health Hiv/aids

Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #19 on: July 11, 2011, 12:53:34 pm »
That article is only relevant to NRTI class meds no longer widely prescribed in the US and EU. The exception being us long term survivors that took those medications in the late 80's through the 90's, and/or people in places like Africa that are still using them.
"I’ve slept with enough men to know that I’m not gay"

Offline james3000

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Re: in your opinion do the meds age your face?
« Reply #20 on: July 11, 2011, 02:55:18 pm »
Well I am on one

Offline mecch

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Re: in your opinion do the meds age your face?
« Reply #21 on: July 11, 2011, 02:56:46 pm »
This topic, this fear, is such a perennial thread in these forums.  Don't enough docs inform people of the current situation regarding lipo and HAART?  Or more that its just a common fear that will never go away, no matter what doctors and research say?
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline james3000

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Re: in your opinion do the meds age your face?
« Reply #22 on: July 11, 2011, 03:08:41 pm »
In his article the research is new. For myself I do not have any fear of aging and recommend use of cheap moisturiser everyday twice a day.
With the HIV meds it is not a one size fits all situation.

Offline Zohar

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Re: in your opinion do the meds age your face?
« Reply #23 on: July 11, 2011, 04:28:26 pm »
Who cares what you look like. Be thankful you're alive and will be for years to come.



Y'know, I kinda agree with this and anyone who's seen advanced HIV disease knows that it's not an attractive look.

However, there's little doubt that some people with HIV feel less desirable because of the stigma attached to the disease, and so it's not surprising that people also fear medications taking a toll on their looks.
At a subconscious level most people are aware of the fact that being alive is more important than what we look, but the world in which we live is staggeringly looks-obsessed, so HIV and possible visible effects of the medication will inevitably be a concern for some.

And directly related to all of this is the minefield of finding a partner, where it seems that the more youthful one appears, the more desirable one is.

Anyway, having said all of this, I've received some very flattering comments recently, so whether I look older or not, I get the impression that I'm certainly looking better!

''Poor is the man whose pleasures depend on the permission of another.''

Offline Matty the Damned

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Re: in your opinion do the meds age your face?
« Reply #24 on: July 11, 2011, 06:07:13 pm »

MtD

Offline Inchlingblue

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Re: in your opinion do the meds age your face?
« Reply #25 on: July 11, 2011, 07:47:01 pm »
Once you hit 40, regardless of HIV, you start looking haggard (unless you're George Clooney). Did you see Brad Pitt in Tree of Life yet? Poor thing is looking a bit bloated.


Sugar muffin, it's called Radiesse (or Juvederm, take your pick). Even those without overt lipo partake in facial fillers, especially in Hollywood.
« Last Edit: July 11, 2011, 08:47:33 pm by Inchlingblue »

Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #26 on: July 11, 2011, 09:01:42 pm »
Well I am on one

Specifically which one?
"I’ve slept with enough men to know that I’m not gay"

Offline surf18

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Re: in your opinion do the meds age your face?
« Reply #27 on: July 11, 2011, 09:24:42 pm »
well i bought the exensive moisturiser mentioned in the beggining of the thread. and i ll drink more water. and ill look into more botox.im already doing that.ha
thanks all!

Offline surf18

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Re: in your opinion do the meds age your face?
« Reply #28 on: July 11, 2011, 09:25:44 pm »
and the post zohar wrote was spot on

Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #29 on: July 11, 2011, 09:30:02 pm »
There's something to be said for aging gracefully.
"I’ve slept with enough men to know that I’m not gay"

Offline phildinftlaudy

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Re: in your opinion do the meds age your face?
« Reply #30 on: July 11, 2011, 09:35:10 pm »
There's something to be said for aging gracefully.
You took the words right out of my mouth Ms. P.
I love it when people say that I "don't look my age;" "that I look young for my age;" "I can't believe you are 44..." etc. and I know that it is all natural ---- I think that one's attitude towards aging and the aging process has a lot to do with how one "looks" as one ages.

The gray hairs in my goatee are distinguished - or so my friends tell me...
The slight wrinkles I have by my eyes show experience and a person who has lived and viewed life -
and the wrinkles I have from smiling - speak for themselves....

Now, brazilian butt implants ---- hmmmm, maybe - but that has nothing to do with aging  ::)
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10/08  636    35  510   9/09 473  38 2900  12/4/09 Atripla
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Offline wolfter

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Re: in your opinion do the meds age your face?
« Reply #31 on: July 12, 2011, 06:47:26 am »
I love what Dolly wrote in her book about aging gracefully, she plans to fight it every step of the way.  I think for many of us who thought we'd be rotting corpses by now, these signs of aging are a badge of honor.

I've kinda reached that point where I focus on the things I can change and disregard what I can't.  I mentioned a class reunion earlier and a conversation occurred that could have caused some hurt feelings had I not bit my tongue.  I hadn't seen Kim in 25 years and she was the most beautiful creature ever back then.  Within 5 minutes of hugging and catching up, she looked at me and said, "gee, you've sure lost a lot of hair, have you thought about doing anything for it?"  I was checking out her 60 lb ass and was so close to asking if she had considered consulting Jenny Craig.... ;)
Being honest is not wronging others, continuing the dishonesty is.

Offline surf18

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Re: in your opinion do the meds age your face?
« Reply #32 on: July 12, 2011, 07:25:52 am »
hahhha wolfer that was great.
its amazing that woman can say such stupid things to men like that but if we ever mentioned say thier ass spread were dead meat.

Offline james3000

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Re: in your opinion do the meds age your face?
« Reply #33 on: July 12, 2011, 08:59:34 am »
Dear Miss P

I am on 3tc Isentress, Intelence, Prezista and Norvir

3tc is a NRTI

Offline james3000

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Re: in your opinion do the meds age your face?
« Reply #34 on: July 12, 2011, 09:06:01 am »
Says right here on poz.com

"HIV drug regimens containing NRTIs, including Epivir, can cause increased fat levels (cholesterol and triglycerides) in the blood, abnormal body-shape changes (lipodystrophy; including increased fat around the abdomen, breasts, and back of the neck, as well as decreased fat in the face, arms, and legs), and diabetes. These side effects of HIV drug therapy are reviewed in our lessons on Lipodystrophy, Facial Lipoatrophy, and Risks To Your Heart (Hyperlipidemia)."

I have seen no ticable increase with fat around abdomen.
 

Offline buginme2

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Re: in your opinion do the meds age your face?
« Reply #35 on: July 12, 2011, 09:21:53 am »
Dear Miss P

I am on 3tc Isentress, Intelence, Prezista and Norvir

3tc is a NRTI

Thats quite the unconventional treatment you are on.  Why are you on this regimin.  Did you have resistance issues.  Ive heard of adding issentres to a pi/2 nrti regimen but havent heard of yours before. Just curious.
Don't be fancy, just get dancey

Offline james3000

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Re: in your opinion do the meds age your face?
« Reply #36 on: July 12, 2011, 09:33:06 am »
Buginme,

Yes I started out with significant resistance also having a problem maintaining the level of drugs in my system seems that I metabolise the drugs fast.
Never missed a dose and take them on time.
Last time I had taken the Durance at the correct time and the research showed there was none detected in my blood.
The next test will be end of July and will not know until end of August if everything is working ok

Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #37 on: July 12, 2011, 12:37:25 pm »
James, in my opinion the article mostly is referring to NRTI's like AZT, Zerit (no longer used in the US), Hivid (also no longer used) and probably Videx. Every NRTI has the general disclaimer about fat levels and body shape changes, but some are seen as much more of a possibility than others, hence why some are no longer prescribed and others are. IMO Epivir is less likely to cause this, though of course not impossible. Same with Viread which is in Truvada, and is the most currently prescribed NRTI for that reason.

I took Epivir in the mid-90's. Whether or not it is responsible, or partially so, for my own lipoatrophy and neuropathy issues I can not say, as I also took all the other NRTIs back then. I would put more blame on Zerit and Hivid for these issues, which is why nobody uses them now. At any rate that's really what the article you linked to was talking about.
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Offline Ann

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Re: in your opinion do the meds age your face?
« Reply #38 on: July 12, 2011, 01:03:29 pm »
which is why nobody uses them now.

Aside from people in third world countries, that is. Better a bit of lipo than dead, eh? I hope the cost of other meds come down soon so they don't have to continue to struggle with the older, more toxic meds.
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HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #39 on: July 12, 2011, 05:34:23 pm »
Aside from people in third world countries, that is.

Please do try and keep up, dear
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Offline Inchlingblue

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Re: in your opinion do the meds age your face?
« Reply #40 on: July 12, 2011, 08:36:19 pm »
Please do try and keep up, dear

Ann, she's a spoiled little bitch who needs a spanking . . . just ignore her.

Offline Ann

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Re: in your opinion do the meds age your face?
« Reply #41 on: July 12, 2011, 09:12:01 pm »
Please do try and keep up, dear

Ann, she's a spoiled little bitch who needs a spanking . . . just ignore her.

And which one of you is going to man-up and give me said spanking? My money is on Inch. Take that you baldy-headed bitch person. :P
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Offline surf18

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Re: in your opinion do the meds age your face?
« Reply #42 on: July 12, 2011, 10:44:11 pm »
ok so the consenus is the meds im on are not aging me?
no onelse has noticed looking ten years old after starting newer meds?
thanks again
ill do the spa day with miss p
 i ll drink more water
and i bought the expensive face cream

Offline Hellraiser

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Re: in your opinion do the meds age your face?
« Reply #43 on: July 13, 2011, 03:28:04 am »
And which one of you is going to man-up and give me said spanking? My money is on Inch. Take that you baldy-headed bitch person. :P

I'll spank you, come here and drop trou.

Offline Inchlingblue

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Re: in your opinion do the meds age your face?
« Reply #44 on: July 13, 2011, 03:31:47 am »
ok so the consenus is the meds im on are not aging me?
no onelse has noticed looking ten years old after starting newer meds?
thanks again
ill do the spa day with miss p
 i ll drink more water
and i bought the expensive face cream

I had a similar experience to what you're describing but it's impossible to know how much, if any of it, is to be blamed on the meds. And there is also, as Miss P attests, natural aging involved as well.

I'm 48 and up until about 6 years ago (when I was 42) I looked about 10 years younger. I suspect that it was around age 42 that I got HIV and, since that time, I've noticed that I'm aging at a slightly faster rate than before. I started meds in July 2008 (Isentress/Truvada) but even before then I was noticing changes in my face and body happening at a faster rate than before. Nothing super major or dramatic, it's not like I looked like Skeletor overnight, but the aging starting to happen faster than before.

Overall I still look good and I say that not to sound conceited but because its true and in order not to scare anyone from meds.

It's very difficult, no, impossible, to be able to really dtermine if aging is accelerated and then to parse how much of it is due to HIV itself, how much is due to the normal aging process, how much is due to the meds, etc.

The bottom line is that it's not anything like what people experienced on the early meds, especially, as Miss P, mentions, AZT, Videx and Zerit.

Are later generation NRTIs  such as Truvada (or any of the later meds for that matter) causing undue mitochondrial toxicity? There should be a study to determine this.

I've had very good overall experience with the meds I'm taking but I wouldn't mind ditching the Truvada the first chance I get (i.e. as soon as an effective nuke-sparing combo is proven to work, such as Isentress/Reyataz).

Also, in my own non-scientific observation, I believe that exercise, in addition to eating healthfully, helps stave off the effects of Time.

And which one of you is going to man-up and give me said spanking? My money is on Inch. Take that you baldy-headed bitch person. :P

Does this man I get an invitation to Mann?
« Last Edit: July 13, 2011, 03:35:56 am by Inchlingblue »

Offline wolfter

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Re: in your opinion do the meds age your face?
« Reply #45 on: July 13, 2011, 07:33:08 am »
And which one of you is going to man-up and give me said spanking? My money is on Inch. Take that you baldy-headed bitch person. :P

All my toys have been packed up for a while, but I'm sure I could assist.  Been a long time and sounds like fun!
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Offline mecch

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Re: in your opinion do the meds age your face?
« Reply #46 on: July 13, 2011, 02:52:07 pm »

I'm 48 and up until about 6 years ago (when I was 42) I looked about 10 years younger.

I gingerly suggest this "10 years younger" was standard gay willed "youthfullness".  Its an easy enough trick that so many gay guys seem about 10 years younger looking than straight guys. 

But the gay eye adjusts VERY quickly, and experts can judge the age amazingly well. 

Then there are the deluded types who truly believe they look 10 or even 20 years "younger".  Best to avoid.  Not that anyone in this forum would be guilty of that.  ;D
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Offline Miss Philicia

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Re: in your opinion do the meds age your face?
« Reply #47 on: July 13, 2011, 03:21:20 pm »

Then there are the deluded types who truly believe they look 10 or even 20 years "younger".

win
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Offline Assurbanipal

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Re: in your opinion do the meds age your face?
« Reply #48 on: July 13, 2011, 05:12:27 pm »
Me, I was born middle aged.  Add 55 years to that and ...

But I look decades younger. 
5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%
2014 VL UD - 48
2015 VL 130 Moved to Triumeq

Offline OneTampa

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Re: in your opinion do the meds age your face?
« Reply #49 on: July 13, 2011, 05:33:15 pm »
I gingerly suggest this "10 years younger" was standard gay willed "youthfullness".  Its an easy enough trick that so many gay guys seem about 10 years younger looking than straight guys. 

But the gay eye adjusts VERY quickly, and experts can judge the age amazingly well. 

Then there are the deluded types who truly believe they look 10 or even 20 years "younger".  Best to avoid.  Not that anyone in this forum would be guilty of that.  ;D

SNAP!!

 ;D
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