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Author Topic: Kidney disease due to Genvoya  (Read 3407 times)

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Offline filopoz

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Kidney disease due to Genvoya
« on: October 17, 2017, 06:10:47 am »
I have been taking Genvoya for 48 days already and on my 30th day, I've had my blood test. While my CD4 is 530 and my VL is down to undetectable level, my kidney markers are not good as my creatinine went up to 129 and eGFR=60 from the normal level before starting the treatment. I have my blood retest and urine test last week and got an e-mail that we need to discuss further. Is there anyone out there who have a similar experience? Did you switch to other ARV? I kind of worried and my anxiety is killing me now. I still have to wait until next week to meet my ID doctor.
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Offline wardp

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Re: Kidney disease due to Genvoya
« Reply #1 on: October 17, 2017, 07:45:22 am »
Hi, does the numbers actually confirm kidney disease, Or just numbers out of normal range?
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Diagd 20,July 2017. Cd4 289, 21% vld .3,462  atripla 4/8/17, 5/10/17 cd4 384 21%, ud.  complera 4/11/2017 switched to stribild 15/11/17. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, uD cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched  to lamivir and nevirapine  due to kidney issues...jan 10,2019 UD..may 13 2019 ud  cd4 482 28% 14th nov 2019 ud. Cd4 414 .27% cd8 444 29%,may 16 2020,ud ,cd4 741"19.62. Dec 2020.ud.jan21 cd4 453. 25.7% 5/6/21.UD. cd4 621;{27.21%}19/10/21 UD.cd4 420; 28%.apr 19;2022 UD cd4 455' 26%.oct 22,UD, cd4 381,27% 10/4.23 UD CD4 462 29%.2/10/23 cd4 378,28%

Offline filopoz

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Re: Kidney disease due to Genvoya
« Reply #2 on: October 17, 2017, 08:03:19 am »
in some medical website it states that it is an indication of  moderate CKD
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Offline wardp

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Re: Kidney disease due to Genvoya
« Reply #3 on: October 17, 2017, 08:17:33 am »
Pls stop reading webs, it will drive you crazy, try and relax, hopefully your doc will sort it,
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Diagd 20,July 2017. Cd4 289, 21% vld .3,462  atripla 4/8/17, 5/10/17 cd4 384 21%, ud.  complera 4/11/2017 switched to stribild 15/11/17. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, uD cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched  to lamivir and nevirapine  due to kidney issues...jan 10,2019 UD..may 13 2019 ud  cd4 482 28% 14th nov 2019 ud. Cd4 414 .27% cd8 444 29%,may 16 2020,ud ,cd4 741"19.62. Dec 2020.ud.jan21 cd4 453. 25.7% 5/6/21.UD. cd4 621;{27.21%}19/10/21 UD.cd4 420; 28%.apr 19;2022 UD cd4 455' 26%.oct 22,UD, cd4 381,27% 10/4.23 UD CD4 462 29%.2/10/23 cd4 378,28%

Offline Jim Allen

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Re: Kidney disease due to Genvoya
« Reply #4 on: October 17, 2017, 10:07:28 am »
https://forums.poz.com/index.php?topic=67773.0

Your reading too much into a single measurement, snap shot moment. Drink plenty of fluids when taking your meds and follow up with the doctor, sounds like just a settling in concern if everything was okay before.

Take it easy

Jim
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Offline Mightysure

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Re: Kidney disease due to Genvoya
« Reply #5 on: October 17, 2017, 02:27:41 pm »
48 days isn't long enough to "cause" kidney disease. It could be indications of disease, but it occupe be something else. See what your doctor says.
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Offline filopoz

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Re: Kidney disease due to Genvoya
« Reply #6 on: October 21, 2017, 08:02:24 am »
Just an update, my urinalysis turn out fine (no detectable albumin) and so it seems my body is indeed just adjusting with the medication. My GP and ID doctor also suspect that my herbal medicine for hayfever, whose active ingredient is astragalus, might be the cause of this so I stop it immediately. Anyway, we will monitor closely my kidney markers. Thanks for the positive feedback guys....I feel so thankful also with both my GP and ID doctors for making sure not only to keep the virus at bay but also in managing any side effects of the treatment.
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Offline Jim Allen

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Re: Kidney disease due to Genvoya
« Reply #7 on: October 21, 2017, 08:16:21 am »
Glad to hear you are fine.

You shouldn't be taking anything herbal or over the counter without checking with your doctor to be honest.

I would say good lesson in not panicking or jumping to conclusions. ;)

Take it easy

Jim
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HIV 101 - Everything you need to know
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Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
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Read about PEP and PrEP here
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