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Author Topic: HIV Medications May Raise Susceptibility to Syphilis  (Read 2201 times)

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Offline POZ Editors

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HIV Medications May Raise Susceptibility to Syphilis
« on: January 18, 2017, 10:00:48 am »
The effects of antiretrovirals (ARVs) on certain mechanisms of the immune system may make individuals more susceptible to syphilis. These findings from a mathematical modeling study, which may apply to those taking ARVs as pre-exposure prophylaxis, or PrEP, in addition to those using them for HIV treatment, may help explain the recent surge in syphilis rates among men who have sex with men (MSM).

While the number of syphilis diagnoses in the United States is much smaller than those of chlamydia and gonorrhea, the syphilis rate is rising much faster than the rates of the other two major bacterial sexually transmitted infections (STIs). Annual syphilis diagnoses rose 128 percent (from 8,700 to 20,000) between 2005 and 2014; chlamydia diagnoses rose 48 percent (from 976,000 to 1,442,000); and gonorrhea diagnoses rose 3.1 percent (from 340,000 to 350,000).

Read more...
https://www.poz.com/article/hiv-medications-possibly-including-prep-may-raise-susceptibility-syphilis

Offline CaveyUK

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Re: HIV Medications May Raise Susceptibility to Syphilis
« Reply #1 on: January 21, 2017, 02:53:05 pm »
Will be interesting to see where this goes, although I tend to be a little sceptical about mathematically-modelled studies when large scale 'real world' studies do not reach quite the same conclusion (as per the article). Would be also interesting to see stats post 2014 as this would reflect a period where far higher number of people are on PrEP.
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Offline Mightysure

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Re: HIV Medications May Raise Susceptibility to Syphilis
« Reply #2 on: February 01, 2017, 05:07:08 pm »
Kind of skeptical of this.  Maybe it's a behavioral and social thing.  Like people on HIV medications may come in contact with people with syphilis.

 


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