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Author Topic: New Mutation!!  (Read 8265 times)

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Offline thunter34

  • Member
  • Posts: 7,305
  • His name is Carl.
Re: New Mutation!!
« Reply #50 on: January 10, 2007, 02:50:44 PM »
Muchas gracias!
AIDS isn't for sissies.

Offline pozguy75

  • Member
  • Posts: 1,239
    • POZitively Speaking
Re: New Mutation!!
« Reply #51 on: January 10, 2007, 03:55:27 PM »
Yes, I am totally upfront with my doctor...he knows all...which is good, so it's not like I am behind his back or anything...

And the doctor is also pretty convinced that the study drug Maraviroc wasn't able to keep me undetectable and allowed my virus to blip more that once...so, since being put on Kaletra along with the existing Combivir, my numbers have gone back to undetectable...

Thanks thunter!! Love you man...and no question is sensative question here...that's why I am here...

Thanks Matt for the info too!!

My God you both are going to be living in my dreams tonight! I may even have a day dream as well!!  ;D
Dx 2005
ATRIPLA

Offline thunter34

  • Member
  • Posts: 7,305
  • His name is Carl.
Re: New Mutation!!
« Reply #52 on: January 10, 2007, 05:12:03 PM »
Wuv and hugs and fat, fat sloppy wet kisses, Jeromy!     :-*

I guess the bottom line (and somehow we always end up discussing bottoms with Jeromy- LOL) is that this mutation / blip thing is not as rotten as it first seemed.

That is good to hear.
AIDS isn't for sissies.

Offline pozguy75

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    • POZitively Speaking
Re: New Mutation!!
« Reply #53 on: January 10, 2007, 06:08:01 PM »
I am always the bottom in these situations...
Dx 2005
ATRIPLA

Offline thunter34

  • Member
  • Posts: 7,305
  • His name is Carl.
Re: New Mutation!!
« Reply #54 on: January 10, 2007, 06:12:32 PM »
I am always the bottom in these situations...

Revised to read:  MOST situations!   ;D
AIDS isn't for sissies.

Offline Amosboy

  • Member
  • Posts: 156
  • Music is the panacea.
Re: New Mutation!!
« Reply #55 on: January 10, 2007, 08:40:21 PM »
Jeromy,

I have no doubt that you will end up on top of this "particular" situation.  You have a lot of people sending you the best, myself including.  A little more TLC may be in order.  You'll be doing somersaults before it's all over and everyone will surely give you a STANDING ovation...keep that smile on your face.

Brooks
"Love isn't love unless it's not painfully absurb."

-Charlotte Martin

Offline pozguy75

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    • POZitively Speaking
Re: New Mutation!!
« Reply #56 on: January 10, 2007, 11:50:22 PM »
Nothing but smiles here...and Brooks, yes, kissing is underrated!
« Last Edit: January 11, 2007, 09:19:45 AM by pozguy75 »
Dx 2005
ATRIPLA

Offline GSOgymrat

  • Member
  • Posts: 5,002
  • HIV+ since 1993. INTJ
Re: New Mutation!!
« Reply #57 on: January 11, 2007, 02:11:31 AM »
and Brooks, yes, kissing is overrated!

BLASPHEMY!

Offline lydgate

  • Member
  • Posts: 1,022
  • Virgin, can't drive
Re: New Mutation!!
« Reply #58 on: January 11, 2007, 02:23:17 AM »
Just a typo thing on Jeromy's part, keep the large fonts in check now. Or is it a Freudian (or, horror of horrors, deliberate) slip?!

Kissing rawks.
Her finely-touched spirit had still its fine issues, though they were not widely visible. Her full nature, like that river of which Cyrus broke the strength, spent itself in channels which had no great name on the earth. But the effect of her being on those around her was incalculably diffusive: for the growing good of the world is partly dependent on unhistoric acts; and that things are not so ill with you and me as they might have been, is half owing to the number who lived faithfully a hidden life, and rest in unvisited tombs.

George Eliot, Middlemarch, final paragraph

Offline pozguy75

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    • POZitively Speaking
Re: New Mutation!!
« Reply #59 on: January 11, 2007, 09:19:23 AM »
BLASPHEMY!

OOPS I meant to say Underrated!!

I am revising my reply!
Dx 2005
ATRIPLA

Offline Amosboy

  • Member
  • Posts: 156
  • Music is the panacea.
Re: New Mutation!!
« Reply #60 on: January 11, 2007, 08:20:13 PM »
Jeromy,

I didn't even give the first response a second glance.  Something told me that couldn't be true  ;)  And I was fully prepared to use my magic lasso on you to get to the truth of the matter.  Oh well...you had to go and edit your response.  How do you like the T-shirt design?  "Sluts Unite" actually reads across the back of the shirt...pretty hot, huh?   I hope you are having a blast in DC.



Brooks
« Last Edit: January 11, 2007, 08:22:09 PM by Amosboy »
"Love isn't love unless it's not painfully absurb."

-Charlotte Martin

Offline thunter34

  • Member
  • Posts: 7,305
  • His name is Carl.
Re: New Mutation!!
« Reply #61 on: January 11, 2007, 08:24:06 PM »
Lordy!  Is it DC time for them all already?  If so, that means Catman is also off the boards here.   And who else?  Someone else said they were going to that thing. 

(I'm getting sweaty just thinking about the tales we will hear on their return!)
AIDS isn't for sissies.

Offline aupointillimite

  • Member
  • Posts: 3,229
  • FUS DO RAH!
Re: New Mutation!!
« Reply #62 on: January 11, 2007, 08:25:31 PM »
Wait... Jeromy's in DC?

No fair!  I would've taken some time (and my Suicide Girl friend who does modeling for Club Bound in DC) to go to whatever he's at.

Stupid vacation.   ;)

Have fun in the city of my birth, Jeromy!
Your tastebuds can't repel flavor of this magnitude!

Offline Amosboy

  • Member
  • Posts: 156
  • Music is the panacea.
Re: New Mutation!!
« Reply #63 on: January 11, 2007, 08:29:44 PM »
Now, now boys...I'm sure we'll eventually get to see all of the sordid details on DVD...maybe even a gangbang scene in a hotel room.

Motel 69..."We'll leave the light on...and the lube on the table for you"

In any event, I glad that Jeromy is moving forward and keeping his good spirits about him.  And I'm sure he's making someone very happy right about now.

Brooks
« Last Edit: January 11, 2007, 08:33:20 PM by Amosboy »
"Love isn't love unless it's not painfully absurb."

-Charlotte Martin

Offline RapidRod

  • Member
  • Posts: 15,281
Re: New Mutation!!
« Reply #64 on: January 11, 2007, 08:33:07 PM »
Jeromy, don't sweat it. You will die by screwing yourself to death or by a light rig falling in the tub during a hot erotic filming scene in the bath.  ;)

Offline thunter34

  • Member
  • Posts: 7,305
  • His name is Carl.
Re: New Mutation!!
« Reply #65 on: January 11, 2007, 08:39:55 PM »
I have spied this Suicide Girl of whom Benj speaks.

And she is hot


Like lava hot



(Again, gay...not blind)
AIDS isn't for sissies.

Offline aupointillimite

  • Member
  • Posts: 3,229
  • FUS DO RAH!
Re: New Mutation!!
« Reply #66 on: January 11, 2007, 08:49:34 PM »
I have spied this Suicide Girl of whom Benj speaks.

And she is hot


Like lava hot



(Again, gay...not blind)

I know.  I had her dancing on my coffee table for my Seven Years Still Queer Party last year.

It was an ironic treat for all who attended. 
Your tastebuds can't repel flavor of this magnitude!

Offline gerry

  • Member
  • Posts: 522
  • Joined AM Feb 2003
Re: New Mutation!!
« Reply #67 on: January 11, 2007, 11:43:35 PM »
Hi Jeromy,

The only relevant mutation you have that is known to affect drug susceptibility is the M184V and it does show in the test that the virus is completely resistant to Epivir and Emtriva.  However, I do not see anything in the test that indicates that the virus has reduced susceptibility to AZT, d4T and Viread.

Your dual-tropism may have caused the Maraviroc to fail, which allowed the virus to break through and most likely allowed the development of the M184V mutation (which is the first mutation expected in this situation).  But since it was caught early, it averted development of resistance to AZT (so the AZT in the Combivir is actually still working).

Using Kaletra makes very good sense in this situation; it is potent and has a high genetic barrier against resistance.  That, plus AZT (which tends to work better in the presence of M184V) is likely enough to cause maximal viral suppression.  You are still essentially on dual therapy, even though it may be enough to suppress the virus.  If you wish to add another drug to make sure you have 3 active drugs in the combo, Viread would be the logical one to add.  The M184V also tends to make it work better, so you still want to keep the 3TC.

Cheers,
Gerry

 


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