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Author Topic: Atripla..  (Read 10526 times)

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Offline roscoe

  • Member
  • Posts: 11
  • I'm think im dealing with this pretty good!
Atripla..
« on: December 30, 2006, 03:34:26 AM »
I too am starting to take Atripla tonight.  I was originally concerned about having to take it on an empty stomach. I wasn't too sure exactly what "empty" meant,   and what side effect it could cause. I found "newt"'s info reassuring (thanks). If nightmares are the effects, I guess it could be worse. I have to get in the habit of eating earlier, as this was not the case before. I went to get my lab work done yesterday my Dr wants me back on February 6 for the next one. I'll have my counts at that time, and see if  I am to continue with Atripla or not.  Wish me Roscoe.

Offline zenworks

  • Member
  • Posts: 5
Re: Atripla..
« Reply #1 on: January 02, 2007, 12:31:20 AM »
I just signed up to this site after reading the posts on various topics.  This is a great resource.  Thank you all. 

I have been positive for 10 years and up until recently, med free.  I attribute it to somewhat healthy living, vitamins, the use of the supplement BHT, and luck.  I am now 13 days into taking Atripla.  I was VERY apprehensive about the side effects (and still am) of the med but I understand that this is now much more tolerable than it was 10 years ago.  So far, my side effects have included:
  • headaches (solved by proactively taking advil)
    active dreaming
    insomnia some nights
    rash on my upper torso
    loss of appetite
    dizziness

...and that's it!  I'm very happy so far that that's all I have to worry about.  And I feel blessed that this medication is out which allows taking one pill once per day.  The headaches have gone away after almost 2 weeks (I have been able to alleviate them by taking Advil with the initial dose and then in 4 hour increments... but today I forgot to take any because I did not have any headaches (hooray)...hopefully a constant in days to come.  My CD4 were at 106 and Viral Load at 384,000 upon starting Atripla.

I would like to know if anyone with more months (years?) experience could tell me about some things I may want to watch out for?  In particular, I am curious about lypodystrophy with this med.  I am familiar with the liver and kidney potential effects and as a result am drinking lots of water (Dr. says liver is ok right now...anything to do to proactively boost liver health besides B vitamins?)

Also, have any of you had any experience taking the BHT preservative as a countermeasure to the virus?

Thanks.  and I will keep posting...


Offline phantim

  • Member
  • Posts: 11
Re: Atripla..
« Reply #2 on: January 13, 2007, 05:26:30 PM »
The "take on an empty stomach" warning really applies to the Sustiva (Efavirenz) component of Atripla as high fat/high calorie foods increase the absorption of Efavirenz, hence increasing side effects such as dizziness. It won't necessarily hurt anyone, but might be unpleasant to some.

Offline fondeveau

  • Member
  • Posts: 425
Re: Atripla..
« Reply #3 on: January 13, 2007, 06:07:48 PM »
I asked the doctor and he said not to have anything an hour prior to taking the medicine.  This is to reduce the possible side effects. I've found that it doesn't *bother* me at all, if I've had a light snack prior to bed or even have a slight snack of Atripla with ice cream or pie at bed time - lol.

Offline Tucsonwoody

  • Member
  • Posts: 396
Re: Atripla..
« Reply #4 on: January 16, 2007, 05:57:35 PM »
Some more info about Atripla for anyone interested -

I have been taking it as my first and only hiv med (so far) since November 27, 2006.  At that time my viral load was 196,000.  Three days later, along with some other blood tests they did a viral load and in three days on Atripla it had dropped to 12,000.  Hopefully the numbers are correct and not a case of one or both of them being screwed up.  I didn't get a CD4 count for the November 30th blood test but on 11/27/06 it was 21.

Today I had another blood test and will get results for CD4 and VL in a couple of weeks...will be interesting to see what they are.

And I wished for guidance, and I wished for peace
I could see the lightning; somewhere in the east
And I wished for affection, and I wished for calm
As I lay there - Nervous in the light of dawn

Offline AustinWesley

  • Member
  • Posts: 815
    • HIV Discussion Group on Myspace!
Re: Atripla..
« Reply #5 on: January 30, 2007, 02:35:16 AM »
I just signed up to this site after reading the posts on various topics.  This is a great resource.  Thank you all. 

I have been positive for 10 years and up until recently, med free.  I attribute it to somewhat healthy living, vitamins, the use of the supplement BHT, and luck.  I am now 13 days into taking Atripla.  I was VERY apprehensive about the side effects (and still am) of the med but I understand that this is now much more tolerable than it was 10 years ago.  So far, my side effects have included:
  • headaches (solved by proactively taking advil)
    active dreaming
    insomnia some nights
    rash on my upper torso
    loss of appetite
    dizziness

...and that's it!  I'm very happy so far that that's all I have to worry about.  And I feel blessed that this medication is out which allows taking one pill once per day.  The headaches have gone away after almost 2 weeks (I have been able to alleviate them by taking Advil with the initial dose and then in 4 hour increments... but today I forgot to take any because I did not have any headaches (hooray)...hopefully a constant in days to come.  My CD4 were at 106 and Viral Load at 384,000 upon starting Atripla.

I would like to know if anyone with more months (years?) experience could tell me about some things I may want to watch out for?  In particular, I am curious about lypodystrophy with this med.  I am familiar with the liver and kidney potential effects and as a result am drinking lots of water (Dr. says liver is ok right now...anything to do to proactively boost liver health besides B vitamins?)

Also, have any of you had any experience taking the BHT preservative as a countermeasure to the virus?

Thanks.  and I will keep posting...



Thank you for your post.  I'm nearing the point where I may start on meds and will likely go with Atripla.   I appreciate your detailed list of these mild effects.   I would be happy to have a loss of appetite ;)   I've talked to a few of my friends who are on Atripla and haven't heard anyone yet who has had any horrible effects that have continued.  Your's has been the most thorough report and helpful to me because it's detailed.

There are a few other threads about Atripla going that might be of interest to you.  I don't know how to incorporate the links here for ya, can someone help with that? 
Diag. 3/06  Infected aprx. 2 mo. Prior
Date        CD4   %      VL
4/6/06     627    32    36,500     NO MEDS YET!
6/7/06     409    27    36,100
8/23/06   408    25     22,300
1/2/07     354    23     28,700
2/9/07     139    30     23,000  Hep A Vaccine same day???
2/21/07   274    26     18,500 
3/3/07    RX of Truvada/Sustiva Started.
4/5/07    321     27      Undectable 1st mo.  
5/16/07  383     28    Undectable 2nd mo.
8/10/07  422     32   UD <48 on new scale!

Offline roscoe

  • Member
  • Posts: 11
  • I'm think im dealing with this pretty good!
Re: Atripla..
« Reply #6 on: February 07, 2007, 01:40:34 AM »
Can anyone offer any insight or comments, please? I went to see my Dr today. I found out that my CD4 count is at 396 and my viral load is at 310. Keep in mind that these were taken before I started taking Atripla (Dec. 30). I understand that 310 is at the 'low' end of the scale, and we are trying to get it down to undetectable. My CD4 is also on the 'low' end, but these we want higher. 500 or 1500 is where I want to be. My Dr is continuing me on Atripla, and my next counts will show if it is working for me. I am not really sure how to feel about this.  ???  Any comment will be helpful. Thanks, Roscoe.

Offline fondeveau

  • Member
  • Posts: 425
Re: Atripla..
« Reply #7 on: February 07, 2007, 07:15:46 AM »
Well, I suppose it saves you a trip, if you don't get the blood work done in advance of seeing the doctor.  If you started Atripla December 30 and saw the Doctor again on Feb 6, I would have thought you should have had blood work on January 23.

Anywho, I was CD4 385 and VL 30,000, when I started Atripla and bloodwork taken 3 weeks later showed CD4 500 and VL 300.  The doctor expected the drop in VL and was extremely pleased with the jump in CD4 - he indicated that if often takes a year or more to achieve a climb like that.

 I just had more blood drawn and see my doc on the twentieth, so I hope to be undetectable and even higher on the CD4s.  We shall see.  I don't think you should feel strange at all except it doesn't seem that you would be offered treatment at all with such a low VL without meds.
« Last Edit: February 07, 2007, 07:18:42 AM by fondeveau »

Offline Lou-ah-vull

  • Member
  • Posts: 948
Re: Atripla..
« Reply #8 on: February 08, 2007, 05:55:48 PM »
I am starting Atripla tonight (see thread in Living With...) and a bit anxious about the side effects.  I am out in Palm Springs on a small vacation before a conference next week....so a week away from regular work seems like the best time for me to switch.  Plus, my prescription ran out today anyway.  Any suggestions or experiences you all have had, especially with the when I can eat and how much time between then and taking Atripla before bed will be helpful.

Gary
Diagnosed Oct. 2005
10/05:  367 (26.2%), 24556 VL
01/06:  344 (24.6%), 86299 VL
04/06:  374 (22.0%), 87657 VL
05/06:  Began HAART 05/15/06, Combivir/Kaletra
07/06:  361 (27.8%), 1299 VL
10/06:  454 (32.4%), 55 VL
01/07:  499 (38.4%), UD
02/07:  Switched to Atripla 2/8/07
04/07:  566 (37.7%), UD
08/07:  761 (42.3%), UD
06/08:  659 (47.1%), UD
01/09:  613 (43.8%), UD
07/09:  616 (47.4%), UD
01/10:  530 (44.2%), UD
07/10:  636 (48.9%), UD
01/11:  627 (48.2%), UD
07/11:  840 (52.5%), UD
01/12:  920 (51.1%), UD
07/12:  857 (50.4%), 40
10/12:  UD
01/13:  710 (47.3%), UD
07/13:  886 (49.2%), UD
01/14:  985 (46.9%), UD
06/14:  823 (47.2%), UD

Offline fondeveau

  • Member
  • Posts: 425
Re: Atripla..
« Reply #9 on: February 08, 2007, 07:37:07 PM »
No side effects here.  Doc said an hour after something light, maybe two hours after a fuller meal.  Take with a glass of water at bed time and sweet dreams.

Offline onemoretime

  • Member
  • Posts: 142
Re: Atripla..
« Reply #10 on: February 13, 2007, 11:13:10 PM »
Hey guys,  I just got my password issue resolved so i can post.  I started on truvada sustiva last dec 05, it was after a year and a half of being med free after diganocis.  my numbers were ok all along, cd4 480,390 range, vl was 50k to 60k, so we normally would not have started me on meds but my heb b vl was 1.1 billion. so we started me on meds.  VL went und for both hiv and hpb.   cd4 shot up to 710 for 6 months then went to 460.   Never had any side effects from truvada sustive.  I had 6 months of meds in drawer, so i will be changing to atripla in another month. love the one pill idea
08/04 diag 490 cd4 vl 50,000
10/25/05 436 50,513 hvb 1.1 billion
12/13/05 truvada sustiva
02/16/06 742 und, hpb 63,000
04/27/06 740 und hpb 60,000
01/05/07 458 und hvb und
03/08   470 undetectable still on atripla. Non smoking (chantex)
08/08 cd4 550 undetectable hiv, Hep B UND. Atripla
06/09  cd4 444, vl undetectable testo 130
09/09/09 CD4 687 46% UND  Testo 213 started androgel
10/12/09 cd4 682 46% und testo 597
01/12/10 cd4 842 48% und testo 434
041010 cd4 693  53% testo 492
100410 cd4 568 48% testo 523
012711 cd4 523 hcv 56 testo 596
083011 cd4 280 Hcv/HIV und
042912 cd4 158 hcv /hiv und, was on hep c for 11 months. do have ssdi filed and getting LTD
061912 cd4 151, bactrum, hep c and hiv und
071712 cd4 287 52% HIV HCV und
112012 cd4 520

Offline BlkRedBonenla

  • Member
  • Posts: 85
    • My MySpace Page
Re: Atripla..
« Reply #11 on: February 23, 2007, 11:19:26 AM »
Like the first poster, I just got my first prescription for ATRIPLA and may start tonight as well. I have been positive for 7 years and med free, but after a recent stay in the hospital with pneumonia, I am rethinking my alternative approaches as a sole treatment. Being in a hospital bed will make you rethink many things!! I was emphatic with my doctor that I wanted a drug treatment with [1] MINIMAL SIDE EFFECTS, [2] NO AZT, and [3] NO LIPO SIDE EFFECT.

Any vouch for that?
- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline DanKenny

  • Member
  • Posts: 147
Re: Atripla..
« Reply #12 on: February 24, 2007, 12:02:28 AM »
I am a week into Atripla, and so far side effects have been:

-- minimal headache
-- no rashes
-- no vivid dreams (though I wish I had some)
-- no diarrhea
-- but lots of dizzyness, especially in the mornings. This is subsiding, so far.

Be hopeful.  It seems like a tolerable regiment.  I wish you best.

rgds, DK
My Progress:

09/07:   771   ~    <50     ~   29%
03/07:   493   ~    227      ~   22%
02/07:   Began Meds ~~ ATRIPLA
01/07:   315   ~   45, 000  ~   18%
10/06:   350   ~   32, 430  ~   22%
04/06:   440   ~   23, 997  ~   24%
07/05:   621   ~   36,000   ~   24%
01/05:   842   ~   2306      ~   28%
07/04:   615   ~   3370      ~   27%
04/04:   674   ~   739        ~   26%
11/03:   439   ~   2800      ~   22%
Infected probably around 1997 / Diagnosed 2002

Offline bhh1020

  • Member
  • Posts: 8
Re: Atripla..
« Reply #13 on: February 25, 2007, 05:55:27 PM »
Thank you for your post.  I'm nearing the point where I may start on meds and will likely go with Atripla.   I appreciate your detailed list of these mild effects.   I would be happy to have a loss of appetite ;)   I've talked to a few of my friends who are on Atripla and haven't heard anyone yet who has had any horrible effects that have continued.  Your's has been the most thorough report and helpful to me because it's detailed.

There are a few other threads about Atripla going that might be of interest to you.  I don't know how to incorporate the links here for ya, can someone help with that? 
:-*

I see your CD4 progression.  I have never been on meds before (my CD4 48) but I do feel better after 1 month - NOT great but better.  I would not hesitate getting on meds.  As my Dr. advised the lower the CD4 the tougher and longer it takes to get the level back to a level  that does not require Bactrim and Zythromyiacin.  Best to you!!!!

Offline bhh1020

  • Member
  • Posts: 8
Re: Atripla..
« Reply #14 on: February 25, 2007, 06:00:02 PM »
Like the first poster, I just got my first prescription for ATRIPLA and may start tonight as well. I have been positive for 7 years and med free, but after a recent stay in the hospital with pneumonia, I am rethinking my alternative approaches as a sole treatment. Being in a hospital bed will make you rethink many things!! I was emphatic with my doctor that I wanted a drug treatment with [1] MINIMAL SIDE EFFECTS, [2] NO AZT, and [3] NO LIPO SIDE EFFECT.

Any vouch for that?

I just recently started Atripla - Totally healthy for 21 years until September 2006.  Now on Atripla - week 4.  Stick with it.  The first week can be tough - was for me as far as feeling as though I didnt have control of things but much better now.  I still am not able to work because it is usually mid to late afternoon before I feel "myself" but I would encourage you to GET on meds.  DO NOT hesitate.  I have been positive for 21 years and HAD NO PROBLEMS at all until just late last year.  I feel better after 1 month so I hope you make the decision to get the med therapy. It is worth it!

Offline roscoe

  • Member
  • Posts: 11
  • I'm think im dealing with this pretty good!
Re: Atripla..
« Reply #15 on: February 27, 2007, 04:55:29 AM »
Hello All! It will soon be two months that I have been taking Atripla. For the most part everything has been good. Two days ago I started noticing what I believe to be a small rash on the insides of my thighs and on my butt. I have never had rashes that I can remember, and this one is very itchy. Should I be concerned, should I call my Doc.. ? Does anybody have any advice on this matter. My next visit to Doc.  wont be till April. I hope the rash will be gone by then. Any advise would be appreciated. Thanks, wish my Roscoe.

Offline indyguy

  • Member
  • Posts: 260
  • Hoosier Boy Single Again.
Re: Atripla..
« Reply #16 on: February 27, 2007, 01:24:55 PM »
Two weeks for me and no side effects at all yet.
Meds doing well so far.

Offline heykev

  • member
  • Posts: 2
Re: Atripla..
« Reply #17 on: February 27, 2007, 04:28:17 PM »
Hey, this is my first post to the board. Reading through these messages the past few months has been so
informative and so I feel it is important to contribute when I can.
Just to let anyone who may be concerned about Atripla because of the Sustiva component ect...
I was on Truvada and Kaletra - had constant gut problems for months so my doctor said I could try the
Atripla. I had myself so freaked out about the dreams I had heard about and the drunk feeling that alot
of people had, that I almost did not try it.  I have been on Atripla for three months now and am about to
go back in for my labs. I am so glad I did so far because I have had no side affects with the exception of
some very detailed dreams but they were fun dreams not awful dreams. No stomach problems at all.
I just take it before I go to bed and I have been sleeping like a baby. According to my partner, snoring the
whole night away. So, don't be afraid to try it out.  I am glad I did.

Offline budndallastx

  • Member
  • Posts: 463
Re: Atripla..
« Reply #18 on: February 28, 2007, 06:45:39 AM »
The funny thing about people is that they will post the bad and not the good.   Everyone reacts differently to teach medication and for the majority the side effects are minimal. 
Meds since: 11/20/2006
Sustiva / Truvada
12/08/2008 VL:<48 CD4 622 (38%)   
9/8/2008 VL:<48 CD4 573 (30%)
5/2008 VL:<48 CD4 464 (30%)
1/2008  VL: <50  CD4 425(28%)
9/2007   VL: <50  CD4 465 (27%)
6/2007   VL: <50   CD4 443 (26%)
3/2007  VL: <50   CD4 385 (25%)
12/2006 - VL: <50   CD4: 384 (25%)
11/2006 - VL:  22K  CD4: 208 (18%)

Offline BlkRedBonenla

  • Member
  • Posts: 85
    • My MySpace Page
Re: Atripla..
« Reply #19 on: February 28, 2007, 01:05:39 PM »
I just recently started Atripla - Totally healthy for 21 years until September 2006.  Now on Atripla - week 4.  Stick with it.  The first week can be tough - was for me as far as feeling as though I didnt have control of things but much better now.  I still am not able to work because it is usually mid to late afternoon before I feel "myself" but I would encourage you to GET on meds.  DO NOT hesitate.  I have been positive for 21 years and HAD NO PROBLEMS at all until just late last year.  I feel better after 1 month so I hope you make the decision to get the med therapy. It is worth it!


Thanks for those encouraging words. I have YET to start drinking the Kool-Aid, as it were. My Atripla bottle remains closed and sealed. Then I get an email update from the 14th Conference on Retroviruses & Infectious Disease, going on here in LA. Apparently studies are finding that Sustiva - in Atripla - tends to cause Lipo, which I was told it did not.

I'm still confused.

By the way, my doctor told me that if I develop a rash of any kind after starting meds TO STOP. I guess what adds to my confusions is that it seems different doctors have widely different approaches.
- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline bhh1020

  • Member
  • Posts: 8
Re: Atripla..
« Reply #20 on: February 28, 2007, 02:40:33 PM »
Hi I dont have any info on the LIPO problem.  I see my ID on Friday and will check with him.  The side affects are minimal other than feeling kind of high which is not a bad feeling. Heat rush and then mild high.  If I take the med at 11:00PM CST I am not awake to experience the "high".  I really hope you decide to get on the meds.  PLEASE dont wait much longer. It is worth the fight!
Barry

Offline bhh1020

  • Member
  • Posts: 8
Re: Atripla..
« Reply #21 on: February 28, 2007, 02:43:29 PM »
The funny thing about people is that they will post the bad and not the good.   Everyone reacts differently to teach medication and for the majority the side effects are minimal. 

There is alot of positive info on here. People trying to help each other but at the same time keeping it real. I want to know about the "bad" as far as the good.  But you are right - we all react differently but sharing your experience helps us to know we arent the only one experience common side effects.

Offline RichieRich

  • Member
  • Posts: 4
  • Living and Loving
Re: Atripla..
« Reply #22 on: March 02, 2007, 05:38:26 PM »
I have been taking Atripla for almost a year now.  Before that I was on truvada and sustiva. 
I had the vivid dreams with truvada and sustiva also, and continued having them with the Atripla. 
Sometimes they got unbearable and caused me to be overly tired during the daytime, because my sleep was restless.  It would seem like I was dreaming these bizare dreams all night long, and It drove me MAD.
I took it upon myself to experiment with over the counter pain relievers and found that by taking motrin either with or an hour before taking the Atripla, helped stop my nightmares and vivid dreams.  I continue to take the motrin before I take the Atripla and it stops the vivid dreams.
As far as the Lipo, I have had not problem with any of the meds that I have been taking for the past 7 years.  I hope this continues as I am in great shape, and work out at the gym 4 times a week.
Walk a mile in the other guys shoes!

Offline CWD6474

  • Member
  • Posts: 27
  • 38 year old gay male
    • TulsaChip
Re: Atripla..
« Reply #23 on: March 04, 2007, 04:15:32 PM »
Been on Atripla a week now, and very minimal side effects.. I hope this stays this way..
Grinch

Offline BlkRedBonenla

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Re: Atripla..
« Reply #24 on: March 04, 2007, 09:55:32 PM »
I have been taking Atripla for almost a year now.  Before that I was on truvada and sustiva. 
I had the vivid dreams with truvada and sustiva also, and continued having them with the Atripla...



You've been taking Atripla for almost a year? The FDA approved Atripla in July 2006. How soon after that did you start taking it? I ask because most people here have only just started taking it, and I am looking out for unknown, VIOXX-like side effects to emerge.

- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline pozinbama

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Re: Atripla..
« Reply #25 on: March 05, 2007, 11:45:40 AM »
"By the way, my doctor told me that if I develop a rash of any kind after starting meds TO STOP"

I was told to NOT STOP the meds if a rash develops, unless it is severe and you are having trouble breathing...a rash is very typical and goes away in a few days in most people.

"Apparently studies are finding that Sustiva - in Atripla - tends to cause Lipo, which I was told it did not."

The study compared Sustiva to Kaletra, and said 32% of those on Sustiva developed lipoatrophy, compared with 18% on kaletra. That's basically 30% compared to 20%, not that big of a jump. And that is still less that 1/3 of the people on it, and there seem to be many many variables for who is experiencing it and who is not.

Offline BlkRedBonenla

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Re: Atripla..
« Reply #26 on: March 05, 2007, 12:39:54 PM »
"By the way, my doctor told me that if I develop a rash of any kind after starting meds TO STOP"

I was told to NOT STOP the meds if a rash develops, unless it is severe and you are having trouble breathing...a rash is very typical and goes away in a few days in most people.

"Apparently studies are finding that Sustiva - in Atripla - tends to cause Lipo, which I was told it did not."

The study compared Sustiva to Kaletra, and said 32% of those on Sustiva developed lipoatrophy, compared with 18% on kaletra. That's basically 30% compared to 20%, not that big of a jump. And that is still less that 1/3 of the people on it, and there seem to be many many variables for who is experiencing it and who is not.

I never cease to be amazed and a little troubled the disparity in medical advice given by doctors. I was told to stop meds upon getting a rash; you were told to carry on. Convnetional "wisdom" says stay on the meds, but I have peers whose doctors pull them off when their numbers are good DUE TO THE TOXICITY OF THE MEDICATIONS. Good grief!

To the Lipo issue, a 1/3 is a 1/3 and not something to minimize. Again, my doctor told me the atripla does not cause lipo. This study confirms that it does. My online research confirms that it does. SO I HAVE NOT TAKEN THE MEDS. I will see my doctor this week and inquire further, but someone doesn't know what they're talking about.

Does anyone know, or do we parrot handouts and leaflets?
- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline RichieRich

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Re: Atripla..
« Reply #27 on: March 05, 2007, 01:17:22 PM »
Yes, I started taking Atripla in July of last year.  The only side affect I have is the dreams. 
Don't know why people are scared to take HIV meds, they seem to prevent even colds and flu.  I have been very lucky in my treatment since diagnosed in 2000.  I did have bad diareha prolems when I first started taking HIV meds.  Was taking 4 different scripts back then as my cocktail. 
I am so glad they came up with this once a day med, and I tollerate the vivid dreams as my only side effect, but found on my own that by taking motrin at night, it pretty much helps me get a great nights sleep.
Hope this answers your question BlkRedBonenla.
Walk a mile in the other guys shoes!

Offline BKNYLivin

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Re: Atripla..
« Reply #28 on: March 06, 2007, 11:22:26 PM »
Been on Atripla for 3 weeks now with some sides, but nothing major - dreams, dizziness, insomnia and some itching(apart from the insomnia the other sides seem to be settling down as my body gets used to it). As far as Lipo goes, this was also an issue for me before I started meds and seeing as Atripla=Sustiva+Truvada, I was told by my doctor it was a possibility. Maybe not as common as some of the other meds, but a possibility nonetheless, which is consistent with the findings of the Sustiva vs Kaletra study in this article(which is the study I believe pozinbama might be referring to). But for the purposes of this discussion(Atripla), here's what it states "As a whole, patients in the Kaletra/NRTI and Sustiva/NRTI groups who used Viread were not statistically more likely to develop lipoatrophy.  However, in the comparison between the two groups, lipoatrophy was seen in 12% of patients taking Sustiva plus Viread vs. 6% of patients taking Kaletra plus Viread.":
http://www.aidsmeds.org/articles/1667_11394.shtml
Diagnosed 9/18/06
10/13/06 - CD4:449, 33%,  VL:>500,000
11/20/06 - CD4: 392  VL:425,000
02/08/07 - CD4: 361, 16.9% VL:133,000
02/13/07 - Started HAART: Atripla
03/08/07 - CD4:401, 23.8% VL:643
06/05/07 - CD4:614, 33.6% VL:225
09/14/07 - CD4:612, 37%  VL: <50
12/14/07 - CD4:582, 38.5% VL:<50
4/11/08 - CD4: 658, VL: <50
3/5/09 - CD4: 847, 49% VL: <50
7/29/09 - CD4: 965, 50.1% VL: <50
12/28/09 - CD4: 925, 49.2% vl <50
9/16/10 - CD4: 1011 vl: <50

Offline risred1

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Re: Atripla..
« Reply #29 on: March 07, 2007, 12:51:08 AM »
If Lipo is a major concern, the fat changes associated with Sustiva based treatment might be considered somewhat in the norm, that the severe wasting or redistribution seems to be associate with Zerit and AZT.

That being said, there are other treatment lines perhaps you can consider that are even more fat neutral such as Reatazz based regimine without the norvir.

You know what is ultimately in store for you with low CD4. Don't those "side" effects from actual illness pose a greater concern than possible lipo effects?
risred1 - hiv +
02/07 CD4 404 - 27% - VL 15k
10/07 CD4 484 - 31% - VL 45k
05/08 CD4 414 - 26% - VL 70k
01/09 CD4 365 - 23% - VL 65k
05/09 CD4 291 - 23% - VL 115k - Started Meds - Reyataz/Truvada
06/09 CD4 394 - ?% - VL 1200 - Boosted Reyataz with Norvir and Truvada
07/09 CD4 441 - ?% - VL 118 - Boosted Reyataz with Norvir and Truvada
09/09 CD4 375 - ?% - VL Undetectable - Boosted Reyataz with Norvir and Truvada
12/09 CD4 595 - ?% - VL Undetectable - VIT D 34 - Reyataz/Truvada/Norvir

Offline BlkRedBonenla

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Re: Atripla..
« Reply #30 on: March 07, 2007, 03:02:05 PM »
You know what is ultimately in store for you with low CD4. Don't those "side" effects from actual illness pose a greater concern than possible lipo effects?

Interesting. Any manifest SIDE EFFECT is a sign of ill health, including lipo. Why fewer people get this is weird. I meet these guys who manifest many side effects, drink more kool-aid for those, and boast how good their NUMBERS are. Honey, your insides are turning on you, don't you get it? The body is not moved by chemicals but by your organs and the more you compromise them the worse off you'll be in the long run.

So it's not to some of us as easy as meds vs. "consequences." Just not that simple.
- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline risred1

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Re: Atripla..
« Reply #31 on: March 10, 2007, 09:56:26 PM »
Well, simplicity is in the eye of the beholder.

Meds supress HIV, and unfortunately there is toxicity associated with them. Fortunately, several med lines are "pretty tolerable". The side effects of all the available meds are fairly well known, from the identified Fat issues, to digestive, nausia etc.

Lipo problems is an obvious concern. I'm not saying I'd be happy with having a lipo problem in trade of reducing HIV. If I have no choice, to stay alive and diesease free, I would make that choice. But the "good" news is, LIPO issues seem largely to be associated with certain class of drugs, and there are those lines which seem to not have a "strong" association with this possibility.

And additional good news is, if you exercise and eat right, you stand a good chance of mitigation.

If I told you the odds of lipo with atripla is 10%, is that worth the risk?

How low would you let your CD4's go before you feel compelled to choose the risk versus the bad stuff that comes with HIV and a supressed immune system? If you worry about your outward appearance on a LIPO issue verus something like getting thrush or KS, I would think at that point, the choice becomes clear.

I know I'm giving you the equivelent of the bum's rush. Where I sit now, I'm close to having to choose myself. My CD 4 is around 400, and I'm looking at the reserach that shows the line for meds is really around 350. Becuase one can tolerate the meds better if you start at this line vs 200.

My doc preferrs a PI treatment 1st, then the Sustiva Based, and then a PI. since I have cholesteral and trigliceride issues, I'm probalby going with Reatazz based treatment first. Now the interesting side effect is my skin my turn yellow, but for the most part, it is temporary. But it is largely fat neutral. And there isn't much to point at from a LIPO standpoint. (I am going to avoid the norvir option and go reataz and epzicom.)

So my question for you ultimately, if you don't like the risk of atripla, what about other lines of treatment?

And I'm not trying to make anything simple or easy, we are all different and have our feelings to consider, but we also have to deal with HIV, so unfortunately, that means at some point treatment or in reality, some Aids Releated Diesease, that can ultimately put you down for the count.

All my best, and I'm being sincere. I'm not trying to criticize. I hope this may help... just doing something.
risred1 - hiv +
02/07 CD4 404 - 27% - VL 15k
10/07 CD4 484 - 31% - VL 45k
05/08 CD4 414 - 26% - VL 70k
01/09 CD4 365 - 23% - VL 65k
05/09 CD4 291 - 23% - VL 115k - Started Meds - Reyataz/Truvada
06/09 CD4 394 - ?% - VL 1200 - Boosted Reyataz with Norvir and Truvada
07/09 CD4 441 - ?% - VL 118 - Boosted Reyataz with Norvir and Truvada
09/09 CD4 375 - ?% - VL Undetectable - Boosted Reyataz with Norvir and Truvada
12/09 CD4 595 - ?% - VL Undetectable - VIT D 34 - Reyataz/Truvada/Norvir

Offline BlkRedBonenla

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Re: Atripla..
« Reply #32 on: March 11, 2007, 06:17:30 PM »
Well, simplicity is in the eye of the beholder.

Meds supress HIV, and unfortunately there is toxicity associated with them.

How low would you let your CD4's go before you feel compelled to choose the risk versus the bad stuff that comes with HIV and a supressed immune system? If you worry about your outward appearance on a LIPO issue verus something like getting thrush or KS, I would think at that point, the choice becomes clear.

I know I'm giving you the equivelent of the bum's rush. Where I sit now, I'm close to having to choose myself. My CD 4 is around 400, and I'm looking at the reserach that shows the line for meds is really around 350. Becuase one can tolerate the meds better if you start at this line vs 200.

So my question for you ultimately, if you don't like the risk of atripla, what about other lines of treatment?

And I'm not trying to make anything simple or easy, we are all different and have our feelings to consider, but we also have to deal with HIV, so unfortunately, that means at some point treatment or in reality, some Aids Releated Diesease, that can ultimately put you down for the count.

All my best, and I'm being sincere. I'm not trying to criticize. I hope this may help... just doing something.


Tomorrow, Monday, will be a week that I have been taking the Atripla. The only side effect so far is insomnia. I started taking it an hour before bed, and some sort of caffeine response kicked in and I slept not a wink! I tried taking it the moment I turn the lights out, but I noticed in a half hour's time some odd feeling washed over me, then sleeplessness. Yesterday I took it at noon, empty stomach. I slept much better last night but for 3 hours I probably couldn't be trusted to turn a stove on. THREE HOURS. Hmm. Tonight I will try taking it three hours before bedtime, because that dizzy, dazed & confused feeling seems perfect for sleep versus the initial caffeine-rush feeling, which kept me up.

I don't want to switch treatments at this point, just want this insomnia to resolved itself.
- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline bhh1020

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Re: Atripla..
« Reply #33 on: March 14, 2007, 01:37:09 PM »
Two months into Atripla and the worst thing is insominia. I have taken Ambien to help with no problems.  Also noted irritability but taking Ativan to help with that. Insomnia is the most difficult thing I am dealing with.

Offline Kellyk

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Re: Atripla..
« Reply #34 on: March 15, 2007, 01:00:41 AM »
I've been on Atripla since November.   Had mild diziness for a few weeks    The vivid dreams haven't gone away.  I told the doc it's almost like a benefit.
lol

Offline BlkRedBonenla

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Re: Atripla..
« Reply #35 on: March 15, 2007, 12:49:13 PM »
Two months into Atripla and the worst thing is insominia. I have taken Ambien to help with no problems.  Also noted irritability but taking Ativan to help with that. Insomnia is the most difficult thing I am dealing with.

I stopped taking atripla at bedtime, as I couldn't sleep either. I take it 3-5 hours BEFORE bedtime, and hour or so before dinner, so my stomach is empty. I sleep like a baby now as the intial buzzed feeling has gone. I see the buzzed/wired coming about and 1-2 hours after taking it and - for me - has gotten less and less. BUT I AM SLEEPING LIKE A BABY NOW!!! So try taking it earlier in the evening or late afternoon.
- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline risred1

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Re: Atripla..
« Reply #36 on: March 17, 2007, 09:40:22 AM »
that is great! How did you determine that earlier in the day would help deal with the insomnia?

Thanks!
risred1 - hiv +
02/07 CD4 404 - 27% - VL 15k
10/07 CD4 484 - 31% - VL 45k
05/08 CD4 414 - 26% - VL 70k
01/09 CD4 365 - 23% - VL 65k
05/09 CD4 291 - 23% - VL 115k - Started Meds - Reyataz/Truvada
06/09 CD4 394 - ?% - VL 1200 - Boosted Reyataz with Norvir and Truvada
07/09 CD4 441 - ?% - VL 118 - Boosted Reyataz with Norvir and Truvada
09/09 CD4 375 - ?% - VL Undetectable - Boosted Reyataz with Norvir and Truvada
12/09 CD4 595 - ?% - VL Undetectable - VIT D 34 - Reyataz/Truvada/Norvir

Offline GAMark

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Re: Atripla..
« Reply #37 on: March 18, 2007, 06:36:58 PM »
I too talke Atripla, and have had no major complaints. As for the side affects, the only real one I have noticed was dreams. Not nightmares, but dreams...very vivid ones, and on occassion minor numbness in my fingers, and hands when I'm driving. Other than that, I am geatful for my med reg...

 :) :)
Mark Metheny

Offline BlkRedBonenla

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Re: Atripla..
« Reply #38 on: March 20, 2007, 03:08:04 PM »
that is great! How did you determine that earlier in the day would help deal with the insomnia?

Thanks!

Elementary, my dear Watson ... I associated the insomnia effect like caffeine. As a coffee drinker I know for myself I can't drink it beyond a certain point in the afternoon. Same with ATRIPLA. About 2 hours in I do get that slight buzz. It was strong the first couple of days, almost drunk. But now just a slight buzz.

However, 2 week in to this treatment, the RASH is forming. My arms first, now my lower legs around my ankles. NOT GOOD!!
- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline roscoe

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Re: Atripla..
« Reply #39 on: April 18, 2007, 12:31:12 AM »
Hi everybody! I went to my Dr. today and my counts are undetectable. I am doing well. !

Offline milker

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Re: Atripla..
« Reply #40 on: April 18, 2007, 10:44:03 AM »
Great news roscoe!!!

Milker.
mid-dec: stupid ass
mid-jan: seroconversion
mid-feb: poz
mar 07: cd4 432 (35%) vl 54000
may 07: cd4 399 (28%) vl 27760
jul 07: cd4 403 (26%) vl 99241
oct 07: cd4 353 (24%) vl 29993
jan 08: cd4 332 (26%) vl 33308
mar 08: cd4 392 (23%) vl 75548
jun 08: cd4 325 (27%) vl 45880
oct 08: cd4 197 (20%) vl 154000 <== aids diagnosis
nov 2 08 start Atripla
nov 30 08: cd4 478 (23%) vl 1880 !!!!!!!!!!!!!!!!!!!!!!!!!!
feb 19 09: cd4 398 (24%) vl 430 getting there!
apr 23 09: cd4 604 (29%) vl 50 woohoo :D :D
jul 30 09: cd4 512 (29%) vl undetectable :D :D
may 27 10: cd4 655 (32%) vl undetectable :D :D

Now accepting applications from blowjob ninjas™

Offline dixieman

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Re: Atripla..
« Reply #41 on: April 18, 2007, 11:26:25 AM »
I'm on Atriplia... oh I wished I could have some good ole nightmares... or at least remember the dreams... but, non to avail... I lost all fat when I was on kaletra.. and zerit... evil drugs with awful side effects... atripila... has been good to me!

Offline lucky

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Re: Atripla..
« Reply #42 on: April 18, 2007, 07:30:57 PM »
Hi, I was diagnosed with HIV June 2004.  Just started on Atripla about 3 weeks ago.  The first week I felt like I had the flu, felt dizzy, nausa, etc.  A few vivid dreams, but they have mellowed out.  It helps to take this med on a empty stomach, if not, I feel somewhat sick in the morning.  I try to take it before 11pm est and I stop eating at least 2 hours before I take it.  I'm not sure what my numbers are yet... I hope they are good.  I see my Dr. in June.. Keep your fingers crossed.  I have moments of despair and not sure what my longivty is.  I have lost some weight and people have noticed, however, it's only like about 10lbs.  Thanks for this website.. I do not have many people to talk to about this and it helps.


Offline BlkRedBonenla

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Re: Atripla..
« Reply #43 on: April 19, 2007, 11:56:42 AM »
Just got my first labs back from a month on Atripla, my first HIV med. My Viral Load is Undetetectable, and my cd4 only went up 3 pts.

Good and Bad news I guess.
- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline budndallastx

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Re: Atripla..
« Reply #44 on: April 20, 2007, 06:37:07 AM »
ACtually the labs are quite good.  Going undetectable in the first month is awesome news.  Don't the sweat the CD4's only going up 3.  The good news is they went up! The CD4 count can swing wildly and I have seen people more intelligent than me say as much as 40% so hang in there ! Do you know what your CD4 percentage was?   
Meds since: 11/20/2006
Sustiva / Truvada
12/08/2008 VL:<48 CD4 622 (38%)   
9/8/2008 VL:<48 CD4 573 (30%)
5/2008 VL:<48 CD4 464 (30%)
1/2008  VL: <50  CD4 425(28%)
9/2007   VL: <50  CD4 465 (27%)
6/2007   VL: <50   CD4 443 (26%)
3/2007  VL: <50   CD4 385 (25%)
12/2006 - VL: <50   CD4: 384 (25%)
11/2006 - VL:  22K  CD4: 208 (18%)

Offline YnotinVA

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Re: Atripla..
« Reply #45 on: April 22, 2007, 11:58:55 PM »
I've been on Atripla for a little over a week now.  Consider myself somewhat lucky as I've only had the dizziness and insomnia.  I was taking my med 1.5 hrs after eating (around 9:30pm)...but since it wasn't allowing me to sleep, I was very tired and still very dizzy in the morning where I couldn't make it into work until after 11:00am (and I was even still a little dizzy going in then).  So my doc had my take it 1 hour before I left to go home from work (this way it would hit me shortly after arriving home).  Then I would eat about an hour or more after I got home.  This way the dizziness was well worn off by the morning and I didn't have the insomnia as much during the night.  I am kind of curious if anyone has any cures for reducing the dizziness?  Sometimes it hits like a load of bricks...sometimes it hits a hour after I take it...sometimes it take 3 hours to hit after I take it.  Anyone know why the difference in "hit" time?   Thanks in advance for any insight guys!

Tony in VA
 ::)

VL 64,000
CD4 336

PS:  I've been procrastinating on taking meds too....so I finally gave in after I recently was hospitalized for pneumonia.  But I told my Doc that I didn't want anything that would have a huge impact on my physical well being...things like mood changes, body/fat change, etc.  He also had told me that I won't get the "waste away" look.  I guess I'll have to wait and see.

Offline NowPoz

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Re: Atripla..
« Reply #46 on: April 23, 2007, 11:01:14 AM »
I am now one week on Atripla and have the same dizzy effects with light naseau and fatigue.  I tested poz in Feb 2007 and my numbers dropped to CD4 80 and VL of 587,000. 
It makes it very difficult to get started in the morning as I am at my job at 7am.
How long will the dizzy effects last?   I associate the naseau to the treatment of OI's.

Offline cjmchgo

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  • Dx 1992
Re: Atripla..
« Reply #47 on: April 26, 2007, 12:46:48 AM »
I'm in my 15th year with HIV and getting ever so close to starting meds. My last counts were 320, 21%, 2500.
My concern is school. I'm taking some pretty intense science classes and will be for the next 1 1/2 year. I'm so afraid starting meds (Atripla) and the side effects, mainly the concentration and insomnia stuff. I have to be totally alert and on my toes for these classes.
I'm thinking of waiting until I have a month off between semesters to start so my body will hopefully have enough time adjust.
Ugh! Sucks to start but the alternative is much worse.  :-\
April/May, 1992: Infected at age 21
Aug 31, 1992: Tested positive
Sep 8, 1992 T-cells 977, 43%
1993-1998: T-cells 675-800
1999-2001: T-cells 500-600
2000-2004: T-cells 425-525 23% VL 500-2000
2005-2008: T-cells 275-375, 20%, VL 950-2500
December 2008: Started Atripla
Dec 2009: T-cells 637, 33%, VL UD
Dec 2010: T-cells 544, 35%, VL UD
Dec 2011: T-cells 596, 41%, VL UD
January 2, 2012 stopped Atripla (CNS issues)
January 4, 2012 started Isentress/Truvada
March 25, 2014 Still on I/T t-cells 673, VL undetectable

 


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