Quantcast

Subscribe to:
POZ magazine
Newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr Instagram
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
December 21, 2014, 05:58:22 AM

Login with username, password and session length


Members
Stats
  • Total Posts: 650048
  • Total Topics: 49619
  • Online Today: 177
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online
Users: 6
Guests: 101
Total: 107

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Forced to Change Meds - Will Build Resistance?  (Read 722 times)

0 Members and 1 Guest are viewing this topic.

Offline pursuit

  • Member
  • Posts: 7
Forced to Change Meds - Will Build Resistance?
« on: July 26, 2014, 02:47:58 PM »
Hi...I have been on Truvada (Emtricibine + Tenofovir) + Efavirenz combo for the past 7 weeks but from the day after tomorrow I will be on Lamivudine (2x daily) + Tenofovir + Efavirenz combo. Will this mean I will be resistant to Emtricibine in the future?

This unfortunate event occurs because what my doctor called common & sudden "disruption" to the supplies. Meds in my country is fully subsidized by govt; while they are all free, even if we can afford to buy, there won't be any available  :(     

A month ago I booked a flight to Bangkok for the second week of August 2014 to see a doctor and get a reserve supply of Atripla. I am afraid the whole plan is in jeopardy as:
1) Drug resistance test is not offered in my country, and even in Bangkok it takes 3 weeks to get the result and I don't have the luxury of taking leave from work and flying there again to decide which meds I should stock up;
2) I am trying my best to lessen the number of pills & frequency (secrecy/hiding)
3) After a full month of struggling and finally getting used to Atripla (Truvada + Efavirenz), I am so scared to start all over again with the new combo I will be taking.

Any logical suggestions? (i.e. CD4 now and CD4 sometimes in the future when Emtricibine becomes available again?? - bearing in mind that drug resistance test in not available in my country yet and med options is very very limited, worrying options for first line treatment is already exhausted and I should move up to the second line)

Thanks all   






Offline Miss Philicia

  • Member
  • Posts: 24,516
  • celebrity poster, faker & poser
Re: Forced to Change Meds - Will Build Resistance?
« Reply #1 on: July 26, 2014, 03:09:43 PM »
Hi...I have been on Truvada (Emtricibine + Tenofovir) + Efavirenz combo for the past 7 weeks but from the day after tomorrow I will be on Lamivudine (2x daily) + Tenofovir + Efavirenz combo. Will this mean I will be resistant to Emtricibine in the future?


No, this will not cause resistance -- why do you think it would? You are not changing regimens due to being resistant. You don't magically become resistant in the absence of resistance issues. Did your doctor not bother explaining any of this to you?
"Iíve slept with enough men to know that Iím not gay"

Offline mecch

  • Member
  • Posts: 12,166
  • red pill? or blue pill?
ďFrom each, according to his ability; to each, according to his needĒ 1875 K Marx

Offline BKKKevin

  • Member
  • Posts: 55
Re: Forced to Change Meds - Will Build Resistance?
« Reply #3 on: July 26, 2014, 11:24:00 PM »
The Thai Red Cross in Bangkok will sell you a 6 month supply of Atripla with a doctors prescription from you home county doctor (what country are you located in)... No need to see a local doctor... They also sell a generic form on Apripla calked Teevir - thirty pills are 1,050 bath ( that works out to $35 USD!)... My partner and I were there last week and got him a six month supply no problem...

What do you mean when you say you are trying to lessen the number and frequency of pills?... Are you skipping days to make you supply of pills last longer?!... If so This is NOT a good idea... This could lead to resistance issues...
« Last Edit: July 26, 2014, 11:28:40 PM by BKKKevin »

Offline pursuit

  • Member
  • Posts: 7
Re: Forced to Change Meds - Will Build Resistance?
« Reply #4 on: July 27, 2014, 01:43:58 AM »
MsP, thanks..... I thought that now I am on emtricibine and then when I return to emtricibine some day in the future, my body will become resistant to it. My doctor is an internist (who is appointed by government to treat HIV/AIDS cases), there is no specialist ID doctor in my city, and every time I see her it is less than a 3 minutes affair.... That's why I learn more through this site.

Meech, thank you sooo much for the link. It clarifies everything I have in my mind right now.

BKKKevin, if my current doctor knows I am going to Bangkok for a reserve supply she will even care less (that's what nurses told me - even changing doctor here is practically impossible). What I meant by "number and frequency of pills" is a single pill a day would be the best ideal (Atripla instead of Truvada + Efavirenz). May I pm you on the recommended doctor in Bangkok?

Offline BKKKevin

  • Member
  • Posts: 55
Re: Forced to Change Meds - Will Build Resistance?
« Reply #5 on: July 27, 2014, 08:12:12 AM »
Yes Pursuit feel free to PM me... You might look at the following websites where people express their experiences...

http://pozboysg.tumblr.com/post/36344282081/bens-letter-seeking-hiv-treatment-in-bangkok

http://pozboysg.tumblr.com/post/37181001620/an-update-on-bens-experiences-getting-hiv-treatment-in

I do not have direct experience with doctors in Bangkok as I live in the North in Chiang Mai.  I use my US doctor and a local doctor here in Chiang Mai...

I would suggest you press your local doctor for a prescription... She should understand  from what you have said that availability of drugs is a issue locally and your best interest is in having a sustainable supply of medication... If not you should look for another doctor that has you best interests in mind!...

Here is also a link to the Red Crosses drug listing and pricing...
http://www.adamslove.org/en-d.php?id=73


Offline eric48

  • Member
  • Posts: 1,207
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
Re: Forced to Change Meds - Will Build Resistance?
« Reply #6 on: July 27, 2014, 08:49:47 AM »
i.e. CD4 now and CD4 sometimes in the future when Emtricibine becomes available again?? -

If the virus is suppressed with one combo or an other, one might think that one combo could possibly yield more CD4 gains than the other.

Scientists have browsed through extensive cohorts and no such effect was observed

If, in your country, they do not use much VL monitoring, then I would suggest you do it in BKK: does not cost that much and available within 48 h. Knowing your VL would certainly be a plus in your educated management 
NVP/ABC/3TC/... UD; CD4 > 1000; CD4/CD8 ~ 2.0   safety stock : 3 months (2013: FOTO= 5d. ON 2d. OFF ; 2014: NCT02157311 = 4d. ON, 3d. OFF)

Offline pursuit

  • Member
  • Posts: 7
Re: Forced to Change Meds - Will Build Resistance?
« Reply #7 on: August 11, 2014, 06:38:20 AM »
BKKKevin and eric48, thanks for your posts. I've just returned from Bkk, saw local doctor there and managed to obtain 4 months worth of Teevir (generic Atripla) from the Red Cross Clinics. I also did whole heaps of bloodwork while there and now just waiting for the result to be emailed to me.

 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.