Quantcast

Subscribe to:
POZ magazine
Newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr Instagram
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
November 26, 2014, 04:01:58 PM

Login with username, password and session length


Members
Stats
  • Total Posts: 647520
  • Total Topics: 49339
  • Online Today: 205
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Still not UD after 1 year  (Read 1500 times)

0 Members and 1 Guest are viewing this topic.

Offline Kalel

  • Member
  • Posts: 9
Still not UD after 1 year
« on: July 18, 2014, 07:01:24 PM »
Hi all, I've being reading this forum for so long, but never posted.  :P

Iíve being taking my meds for around a year now, never missed a single dose (maybe got some a little later, like 3 hours). And even so still not undetectable. (Lamivudina + Tenofovir + Efavirenz)

For me itís really a easy going, no side effects, I drink and have parties once or twice a month, I fell healthy and my CD4 is perfect. My only complain is how my virus seems strong against my treatment.

Not sure if I should search other doctor or still trust this one, I really like him, and my CD4 is doing very well, but is taking soo long for me to get undetectable.

Even now to get the resistance test i would need around 1000 VL, and Iím only 124 now.

07/13 - Probably infected

Date   - CD4    -   VL
08/13 - 594     -  469.956 (start meds)
09/13 - 992,6   - 4.913
12/13 - 966,9   - 3.393
02/14 - 749,1   - 1.441
04/14 - 850,6   - 343
06/14 - 1158,6 - 124

He always says: ďIím pretty confident you will be und. on next exams, itís taking long, but you are healthy, you donít need to worry. Other meds are not as good and easy to take as these ones. Relax for nowĒ

SoÖ I wonder if I should get worried or still trust him.
I'm very worried about getting resistant to these meds... it seems other meds available here in Brazil are not as "simple" as these ones. He mentioned i would need to keep them on a fridge and take 3 times a day. (not sure if he said those things for me to not skip any meds)

Offline leatherman

  • Member
  • Posts: 6,307
  • Google and HIV meds are Your Friends
Re: Still not UD after 1 year
« Reply #1 on: July 18, 2014, 07:20:48 PM »
still trust him.
^^ that

it took me 6.5 yrs on my current regimen to reach and retain UD - which means don't freak out if you get to UD and then the next test bumps up too one hundred-something and then back to UD. CD4s and VL counts by themselves don't mean much and are not straight line functions. It's always about the TREND over 3 tests done over a 4-12+ wk period.

Your cd4s are incredible and 500 used to be called "undetectable" just 5 or so yrs ago. Clearly you are NOT becoming resistant because the numbers are still going the right way.

so trust your doc ;)
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline Kalel

  • Member
  • Posts: 9
Re: Still not UD after 1 year
« Reply #2 on: July 18, 2014, 08:34:04 PM »
Thanks leatherman!!
Good to have an opinion of someone who lives so long with it.
I'm still getting used to it, but it's not as bad as we hear of before having it.

Will wait and hopefully next exams will be UD  ;D

Offline leatherman

  • Member
  • Posts: 6,307
  • Google and HIV meds are Your Friends
Re: Still not UD after 1 year
« Reply #3 on: July 19, 2014, 12:48:58 AM »
Will wait and hopefully next exams will be UD  ;D
I would think so. When you going next? Aug?
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline MadisonTeddy

  • Member
  • Posts: 71
Re: Still not UD after 1 year
« Reply #4 on: July 19, 2014, 08:11:31 AM »
"I drink and have parties once or twice a month,"

Does that mean using drugs? How often and how much are you drinking?

Offline leatherman

  • Member
  • Posts: 6,307
  • Google and HIV meds are Your Friends
Re: Still not UD after 1 year
« Reply #5 on: July 19, 2014, 10:05:24 AM »
Does that mean using drugs? How often and how much are you drinking?
pluh-leaze. That has no bearing on how some people reach UD slowly and some quickly. It's not just the meds, it's about genetics too. Take your silly prudish notions elsewhere  ;) :D
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline Kalel

  • Member
  • Posts: 9
Re: Still not UD after 1 year
« Reply #6 on: July 21, 2014, 07:46:45 AM »
Drink around 3 or 4 doses of vodka with some energetic, or beers...
and Sometimes use ecxtasy, but this is like once every 4 months..

I know I shouldn't but I read a lot about it..
It could affect my CD4 but, last month I used both and my CD4 got even Higher, so just try not to exceed and give time, food and gym for my body to recover well after it.


Offline Kalel

  • Member
  • Posts: 9
Re: Still not UD after 1 year
« Reply #7 on: July 21, 2014, 09:38:12 PM »
I would think so. When you going next? Aug?

Actually September, always get a little nervous days before the exam, that I don't think will ever change..  :o

Offline eric48

  • Member
  • Posts: 1,202
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
Re: Still not UD after 1 year
« Reply #8 on: July 22, 2014, 05:56:16 PM »
It took me one year...

As long as it keeps going down,it is OK
NVP/ABC/3TC/... UD; CD4 > 1000; CD4/CD8 ~ 2.0   safety stock : 3 months (2013: FOTO= 5d. ON 2d. OFF ; 2014: NCT02157311 = 4d. ON, 3d. OFF)

Offline Kalel

  • Member
  • Posts: 9
Re: Still not UD after 1 year
« Reply #9 on: September 17, 2014, 06:32:00 PM »
Hi Again all, after more 3 months, just got my exams again.
My VL fall from 124 to 53 and still not UD  :(

I'm happy cause still falling down, but how came it takes so long for a small number to get UD??

Still worried cause my Log calc is falling down:
from [0,62] to [0,45].
And now to [0,37]. (every 3 months)

I'm really used to this regimen and never miss a dose. So it's really frustrating.

Always wording about getting resistant to this regimen...
Trying my best to stay confident.
« Last Edit: September 17, 2014, 06:44:26 PM by Kalel »

Online mecch

  • Member
  • Posts: 12,069
  • red pill? or blue pill?
Re: Still not UD after 1 year
« Reply #10 on: September 17, 2014, 07:16:58 PM »
Did your doctor to say to worry about any of this?
Me, a layman yep, says you are for all purposes undetectable now and you should stop worrying about resistance. Your adherence seems exemplary.
Pat yourself on the back for dealing with HIV and concentrate on living well.
ďFrom each, according to his ability; to each, according to his needĒ 1875 K Marx

Offline drewm

  • Member
  • Posts: 1,169
Re: Still not UD after 1 year
« Reply #11 on: September 17, 2014, 07:18:07 PM »
I think you are freaking over nothing. As leatherman pointed out "CD4s and VL counts by themselves don't mean much and are not straight line functions. It's always about the TREND over 3 tests done over a 4-12+ wk period.

Your cd4s are incredible and 500 used to be called "undetectable" just 5 or so yrs ago. Clearly you are NOT becoming resistant because the numbers are still going the right way."

Chill. It's OK. You are on track to be UD  ;)
Diagnosed in  May of 2010 with teh AIDS.

PCP Pneumonia . CD4 8 . VL 500,000

ATRIPLA - VALTREX -  FLUOXETINE - FENOFIBRATE


Numbers consistent since 12/2010 - VL has remained undetectable and CD4 is anywhere from 275-325

Offline leatherman

  • Member
  • Posts: 6,307
  • Google and HIV meds are Your Friends
Re: Still not UD after 1 year
« Reply #12 on: September 17, 2014, 08:52:16 PM »
Always wording about getting resistant to this regimen...
that's not how resistance works. Resistance means you've had some, but not enough, meds in your system and the HIV evolves to resist that med. When resistance happens your Viral Load goes up, up, up.

speaking of logs and math, did you notice what your VL number really shows? that since your last test, your viral load has been cut in half! That's definitely not resistance but excellent progress! :D
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline Kalel

  • Member
  • Posts: 9
Re: Still not UD after 1 year
« Reply #13 on: September 17, 2014, 09:45:31 PM »
Thanks all for your words, I think I needed that clarification. (again lol)
Maybe it's really time to stop worrying and let it be on background.  :D

You guys are amazing  ;D

Offline Kalel

  • Member
  • Posts: 9
Re: Still not UD after 1 year
« Reply #14 on: September 23, 2014, 09:41:45 PM »
Hey guys,  just came back from my Doctor.

According to him, I not being UD after 13 months can be considered a 'failure of treatment', for many reasons, not necessary my fault..

So he gave me 2 options:

1) Keep Efavirenz for more 1 single month, and I NEED to get UD. If I do, he will do another exam after 3 months, and I have to keep my UD lvl. So he can wait another 6 months.

2) Change Efavirenz by Ritonavir, it need to be kept in a fridge (what s**ks) and might cause yellowing of the white of my eyes sometimes and other stuff.

He said that I would not get resistant to Efavirenz, so he wanted to try this, and if no side effects I could keep it, or I could back to Efavirenz after some months.


I chose option (1) since I'm so used to my meds, and I would hate to be dependent of a fridge to keep my meds all around.

Any idea if this is really a good choice? Or already had enough of Efavirenz and I should move on?

I found totally weird that he is trying to change my meds since Imy VL is 50
(40 is the minimal to show on exams)
Sometimes get that felling like he is not telling me something...
« Last Edit: September 23, 2014, 09:44:38 PM by Kalel »

Offline drewm

  • Member
  • Posts: 1,169
Re: Still not UD after 1 year
« Reply #15 on: September 23, 2014, 10:27:59 PM »
While I appreciate your concern, I think you are too concerned at this point. Your doc said "not being UD after 13 months can be considered a 'failure of treatment' NOT that it IS a failure of treatment. Obviously, getting to UD is a goal you want to pursue but I am glad to you sticking with your meds for now  ;)
Diagnosed in  May of 2010 with teh AIDS.

PCP Pneumonia . CD4 8 . VL 500,000

ATRIPLA - VALTREX -  FLUOXETINE - FENOFIBRATE


Numbers consistent since 12/2010 - VL has remained undetectable and CD4 is anywhere from 275-325

 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.