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Author Topic: Three more babies?...to be announced at AIDS 2014 in Melbourne  (Read 826 times)

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Offline Jmarksto

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  • Posts: 509

It looks like AIDS 2014 will have some interesting news...the article states:


Three babies have been declared HIV-free after being treated with a revolutionary new drug only hours after they were born.
The fourth child only has 'a very low level' of the virus after receiving the same treatment.
The findings, to be announced at the AIDS 2014 conference in Melbourne from July 20, are a major breakthrough in the fight against AIDS with scientists hoping it could lead to a cure if treatment his received early enough.


http://tinyurl.com/m3z7ow8



There is no doubt some media hype in this, but still very interesting. The article goes on to state that the babies are still on ARVs - so they still don't really know.  The article also eludes to some "revolutionary" new drug, but doesn't state what that is.

03/15/12 Negative
06/15/12 Positive
07/11/12 CD4 790          VL 4,000
08/06/12 CD4 816/38%   VL 49,300
08/20/12 Started Complera
11/06/12 CD4   819/41% VL 38
02/11/13 CD4   935/41% VL UD
06/06/13 CD4   816/41% VL UD
10/28/13 CD4 1131/45%  VL 25
02/25/14 CD4   792/37%  VL UD
07/09/14 CD4 1004/39%   VL UD

Online zettainaoru

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Re: Three more babies?...to be announced at AIDS 2014 in Melbourne
« Reply #1 on: July 01, 2014, 09:13:55 PM »
great news
« Last Edit: July 01, 2014, 09:16:25 PM by zettainaoru »

Online leatherman

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Re: Three more babies?...to be announced at AIDS 2014 in Melbourne
« Reply #2 on: July 01, 2014, 10:56:37 PM »
The article also eludes to some "revolutionary" new drug, but doesn't state what that is.[/size][/font]

Quote
After contracting the virus from their mothers, the four Canadian-born children were given a high dose of three different antiretroviral drugs.
basically the babies were given a form of regular ol' PEP (Post Exposure Prophylaxis)

I have to wonder, since all articles never tell us enough, about the situation these babies were in when they were born. If it was known the mothers were infected prior to the birth, shouldn't the mothers have been put onto treatment so their children were born HIV free in the first place? Otherwise I guess the mothers were diagnosed very late, their babies were then either 1) diagnosed at birth or 2) deemed infected at birth,  before being given medications.

While this may be some interesting information, it seems to me that maybe there's a place for some advocacy there - to ensure that ALL Canadian women are tested for HIV much earlier in their pregnancies. ;)
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline Jmarksto

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Re: Three more babies?...to be announced at AIDS 2014 in Melbourne
« Reply #3 on: July 02, 2014, 01:49:07 AM »
Leatherman;


My understanding of PEP is that is given for a short time (30 days?) and then discontinued, whereas these babies are still on ARVs. 


It seems odd they would refer to ARVs as a "revolutionary" new drug - but perhaps they are referring to one of the newer ARVs.


You are right about the advocacy  to test and treat early in pregnancy - and the article mentions that but it is buried under the hype.


There is no doubt that we will hear more about this during and after the conference.
03/15/12 Negative
06/15/12 Positive
07/11/12 CD4 790          VL 4,000
08/06/12 CD4 816/38%   VL 49,300
08/20/12 Started Complera
11/06/12 CD4   819/41% VL 38
02/11/13 CD4   935/41% VL UD
06/06/13 CD4   816/41% VL UD
10/28/13 CD4 1131/45%  VL 25
02/25/14 CD4   792/37%  VL UD
07/09/14 CD4 1004/39%   VL UD

Online leatherman

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  • Google and HIV meds are Your Friends
Re: Three more babies?...to be announced at AIDS 2014 in Melbourne
« Reply #4 on: July 02, 2014, 05:44:11 AM »
My understanding of PEP is that is given for a short time (30 days?) and then discontinued, whereas these babies are still on ARVs. 
same principle but longer prescription time. right? which makes me wonder, why the longer dosing period? Why hasn't the dosing ended? have they really proven all that much, or really proven anything ? hard to say yet. what does HIV free mean anyway? If the babies were dx'ed positive at birth and put onto meds, aren't they just UD?

So many unanswered questions about an article claiming revolutionary new drugs and "the cure!".
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline Matts

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Re: Three more babies?...to be announced at AIDS 2014 in Melbourne
« Reply #5 on: July 03, 2014, 12:54:32 PM »
I dont know if my link is about the same babies - but if: the babies got AZT, 3CT and Nevirapine. I cannot imagine a new wonder drug; all drugs in the Pipeline are known and far away from a formula for infants.

http://www.theglobeandmail.com/life/health-and-fitness/an-aids-cure-for-kids-a-cautionary-tale/article18414205/
tivicay/kivexa

 


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