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Author Topic: I think my meds are not working  (Read 805 times)

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Offline ramirezolveraalejandro

  • Member
  • Posts: 3
I think my meds are not working
« on: June 28, 2014, 09:07:55 AM »
I was diagnosed on January 2014. I started Atripla next month, with a VL of 400 000 and CD4 320. On April 2014, I reached VL 800 and CD4 600! But then again in June my VL got 8 000 and my CD4 remained 600. I take my pills everyday in the same time, I don't know what happened. My doctor says this growth is still little so we're going to wait two months more to retest. But I'm very disappointed, I think they'll be bad again. I got Hepatitis B vaccination and Pneumococcus vaccination too that month, or perhaps I got reinfected by my new partner. We were so stupid one day that we forgot to use a condom a day, but then we realized it was not good so we stopped it and he didn't finish inside me. I don't know what to think!

Offline Almost2late

  • Member
  • Posts: 233
  • "My disease stops with me" - Jeff G
Re: I think my meds are not working
« Reply #1 on: June 28, 2014, 10:09:00 AM »
The vaccination could cause your viral load to increase something similar happened to me .. But your cd4's look in the normal range ( I'm jealous )..

Good luck 
Atripla, Bactrim, Azithromycin
Date         CD4's          VL
02/14     13  2.79%    228k+
03/14     52       7%       3k-
04/14     not done          2k-
05/14     184     9%       595
06/14     117     8%       235  switched off Atripla
08/14     135    10%      110  stopped Azithromycin
Tivicay, Truvada, Bactrim

“I have heard there are troubles of more than one kind. Some come from ahead and some come from behind. But I've bought a big bat. I'm all ready you see. Now my troubles are going to have troubles with me!”
― Dr. Seuss

“Everybody dies … The thing is, to have a life before we die.”
― John Irving, The World According to Garp

Offline elf

  • Member
  • Posts: 607
Re: I think my meds are not working
« Reply #2 on: June 28, 2014, 09:03:17 PM »
How is your CD4% dynamics?
Let's have a Kiki!

Offline leatherman

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  • Posts: 6,189
  • Google and HIV meds are Your Friends
Re: I think my meds are not working
« Reply #3 on: June 28, 2014, 09:45:57 PM »
feb VL 40000  CD4 320
apr VL 800      CD4 600
Jun VL 8000    CD4 600
not bad statistics at all for 5 months  :D
viral load decrease and cd4 increase are not straight line functions. Both could bounce around during the first year. What you must always care about, and only care about, is the tread. Graph that stuff out. the lines have clearly been down in viral load and up in cd4. When you next test in aug/sept comes back UD/632, think of the worry you will have wasted on this. LOL
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline eric48

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Re: I think my meds are not working
« Reply #4 on: June 29, 2014, 05:02:04 AM »
... or perhaps I got reinfected by my new partner.... I don't know what to think!

Reinfection has been elusive... Always feared but never seen ... Pretty much like the Lock Ness monster

Actually it has been reported once (and only once) , recently, in 1 guy undermeds who go reinfected by a multi resistant virus (or multiresistant partner, if you wish...). This is the only case ever medically reported

If your partner is POZ (not UD) and you are under meds, your meds are acting as PreP , and a virus cannot open shop.

So the re-infection fear is irrational , here...

Once you are UD, and this will come, you stay UD, and you can ... forget about condoms (at least for HIV)
(Now, in various sex situations, I'd stick to condoms because of other STDs)

A viral uptake like this is rare:

feb VL 40000  CD4 320
apr VL 800      CD4 600
Jun VL 8000    CD4 600

Technically, a VL of 8000 would allow a resistance test. Here, they would do it, results take a month anyway... So waiting 2 months for the next test and/or doing resistance test may not be that different, after all

You will soon know what to think ...

Wouls be nice if you could keep posting, once you results are in

Eric
NVP/ABC/3TC/... UD; CD4 > 1000; CD4/CD8 ~ 2.0   safety stock : 2 months

Offline ramirezolveraalejandro

  • Member
  • Posts: 3
Re: I think my meds are not working
« Reply #5 on: June 29, 2014, 11:56:55 AM »
I'm kinda sad and confused guys, perhaps I'm just whinning about anything ( we say pleurnicheur in french or llorón in spanish) But I've been poz since 5 months. I started very positive, and then this stuff (VL increased) just took me in a bad phase. I've read most of the cases people get UD in just one month with Atripla. Doctor says no to be VERY worried at this time, but wait the next VL test. We both hope to be down again.

Offline leatherman

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  • Google and HIV meds are Your Friends
Re: I think my meds are not working
« Reply #6 on: June 29, 2014, 12:21:19 PM »
A viral uptake like this is rare:
not true. getting to UD is very often not a straight-line event. Quite often the VL and CD will "bounce" up and down, which is why following the trend is 1000 times more important than ever worrying about a one-off test result.

I've read most of the cases people get UD in just one month with Atripla.
you've been reading some incorrect information then.  ;) Getting to UD can take anywhere from a few months (6 to 8 wks) or up to a whole year. Some people have even taken years to reach UD (I took 12 yrs worth of meds before sustaining UD). Expecting to reach UD within a month is a very, very unrealistic expectation. Listen to your doctor, if you don't want to listen to us, as he is completely correct. There is no reason to be worried at this time.

Your regimen clearly seems to be working properly, and unless your VL is up next test, you simply have nothing to worry about at this point.
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline ramirezolveraalejandro

  • Member
  • Posts: 3
Re: I think my meds are not working
« Reply #7 on: July 12, 2014, 01:11:18 PM »
Ok. I'll wait next month, but I'm a little relaxed now. My doctor told me is not anything to worry about, but at the sime time he was a little worried. It's just a lot of info, a lot of cases, and I'm just 6 months until I got infected.

Offline Mrmojorisin

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  • Posts: 211
    • My Blog
Re: I think my meds are not working
« Reply #8 on: July 12, 2014, 02:32:44 PM »
 Relax..check out my numbers. It took me over a year to become undetectable.. Like leatherman says..it is all about the trends...
Started Meds On 5/1/2012 Norvair, Truvada, Prezista, and Bactrim

4/17/2012--CD4 83/ VL 353,000  7.0%
5/15/2012--CD4 218/ VL 4,970    14.1%
6/27/2012--CD4 146/ VL 420      6.1%
10/11/2012-CD4-223/ VL-62       9.5%
2/14/2013--CD4-215/ VL-119      13.6%
7/3/2013---CD4-256/ VL-UD       18.0%
10/18/2013 CD4-223/ VL-UD       22.2%
01/23/2014-CD4-381/VL-UD       25.3%--Dropped the Bactrim

"arrrrhhhhh ahhrrhhhhh aaaarrhhh"- Chewbacca

 


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