Quantcast

Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
October 20, 2014, 01:41:17 AM

Login with username, password and session length


Members
Stats
  • Total Posts: 642737
  • Total Topics: 48889
  • Online Today: 183
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: New Single Dose Pill  (Read 581 times)

0 Members and 1 Guest are viewing this topic.

Offline Kardean

  • Member
  • Posts: 45
New Single Dose Pill
« on: April 30, 2014, 06:14:40 PM »
The FDA is expected to approve a new single pill integrase regimen currently being called Trii by the end of summer.  Has anyone with more experience/understanding about hiv meds looked into it, and if so I would be interested in your thoughts.

Offline Miss Philicia

  • Member
  • Posts: 24,205
  • celebrity poster, faker & poser
Re: New Single Dose Pill
« Reply #1 on: April 30, 2014, 06:27:30 PM »
It's simply a combination in a single dose of medications already approved by the FDA: dolutegravir (aka Tivicay), abacavir and lamivudine -- the latter two already have been combined as epzicom.
"Iíve slept with enough men to know that Iím not gay"

Offline Kardean

  • Member
  • Posts: 45
Re: New Single Dose Pill
« Reply #2 on: April 30, 2014, 11:04:37 PM »
Yes, I know.  I guess its already proven itself.  It will be interesting to see if it becomes the NEW single dose choice.  Also be curious to see how doctors embrace it or if they will hesitate with the usual "let's wait and see" approach.

Offline eric48

  • Member
  • Posts: 1,187
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
Re: New Single Dose Pill
« Reply #3 on: May 01, 2014, 05:12:14 AM »
If GSK had rights to Truvada, they would have offered Tivicay + Truvada (rather than + Epzicom). But they don't... competing GSI has those rights

3TC is already off patent and TDF is or should become soon off patent

So may be a Tivicay + Truvada-like pill will be available, one day...

Epzicom (aka Kivexa) has a (small) barrier to entry: a genetic test must be taken before initiation. The once-suspected cardiovascular risk has been ruled out non existant by FDA, but doctors will remain cautious.

Usage rate is
Truvada ca. 70%
Epzicon ca. 30%

I know my Doc is really looking forward to get Tivicay approved here (not yet...)
We discussed it already, althought I do not see any reason I should switch out of Viramune + Kivexa to Tivicay+Kiveva or even Trii, at this time, but it is always cool to have more drugs and options

There is a growing number of patients on Tivicay+Kiveva (aka Tivicay+Epzicom) so I guess those patients will be prompt to opt for Trii

GSK share will be going up, I suppose...

Eric

modified to add: some small trials are on going for Viramune+Tivicay (2 molecules only) as NRTI sparing regimen: that would be of interest to me...
« Last Edit: May 01, 2014, 05:14:54 AM by eric48 »
NVP/ABC/3TC/... UD; CD4 > 1000; CD4/CD8 ~ 2.0   safety stock : 3 months (2013: FOTO= 5d. ON 2d. OFF)

 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.