Quantcast

Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
September 02, 2014, 11:48:25 PM

Login with username, password and session length


Members
  • Total Members: 23381
  • Latest: Jon24
Stats
  • Total Posts: 636956
  • Total Topics: 48353
  • Online Today: 304
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online
Users: 6
Guests: 190
Total: 196

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Biotron's BIT225 can clear out HIV reservoir pools  (Read 772 times)

0 Members and 1 Guest are viewing this topic.

Offline Tadeys

  • Member
  • Posts: 159
Biotron's BIT225 can clear out HIV reservoir pools
« on: December 05, 2013, 03:06:27 PM »
Biotron (ASX:BIT) has published new results from a phase Ib/IIa HIV study suggesting that its lead drug candidate BIT225 can reduce the quantity of virus in HIV reservoir cells.
The company has already published results suggesting that BIT225 can target HIV replication in these monocyte lineage reservoir cells.
The response was greatest in patients with higher total HIV-1 DNA at baseline. As expected, no changes in viral load were observed during the brief treatment period.
The new data were presented by Biotron’s senior virologist Dr John Wilkinson at the Sixth International Workshop on HIV Persistence during Therapy, being held this week in Florida.
The placebo-controlled, randomised study involved 21 patients with HIV-1 infection, of which 14 received BIT225 and the rest a placebo. Patients were dosed over a 10-day period; blood was collected three times during dosing and once during a follow-up visit at day 20.
“The latest results show that BIT225 is able to clear out underlying virus pools from these reservoir cells,” Biotron Managing Director Dr Michelle Miller said.
She said this suggests that the compound could potentially help break the cycle of infection and reinfection with HIV if incorporated into treatment regimens for the virus.



http://lifescientist.com.au/content/health-medical/news/biotron-39-s-bit225-can-clear-out-hiv-reservoir-pools-847784925

 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.