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Author Topic: A few AIDS-free world meeting highlights...  (Read 526 times)

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Offline Tadeys

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A few AIDS-free world meeting highlights...
« on: November 06, 2013, 03:08:19 PM »
"Warner Greene, director of virology and immunology research at the Gladstone Institutes, discussed studies that for the first time mechanistically link the two pathogenic signatures of HIV infection: CD4 T cell depletion and chronic inflammation.

"These discoveries could lead to three promising outcomes—an affordable bridge therapy for the 16 million who currently need but don't have access to antiretroviral therapies (ART), a potential solution for those on ART and who are developing aging-related diseases a decade or more before the non-HIV infected population, and a potential clearing of the latent reservoir that could contribute to a cure for HIV/AIDS," said Dr. Greene."

-------

"Perhaps the most widely discussed option for a cure has been the hope of a vaccine. A number of speakers discussed the various advances, and also setbacks, in the race toward successful vaccination strategies. Nobel Prize winner David Baltimore of the California Institute of Technology noted, "We need a vaccine, but we still don't have an open road in front of us." The key, according to Baltimore, is to not follow models of traditional vaccines but, rather, to "think about the extremely exciting observations that have been made about the kinds of antibodies that patients make in response to a long-term HIV infection." Speakers examined the various promising avenues toward developing an effective vaccine, including very recent work from Michel Nussenzweig and Dennis Burton on producing monoclonal broadly neutralizing antibodies in macaques."

Glad that Dr. Baltimore alludes to Vectored Immunoprophylaxis (VIP) at the meeting.


The link: http://phys.org/wire-news/145208397/researchers-and-clinicians-unite-to-answer-what-will-it-take-to.html








 


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