Meds, Mind, Body & Benefits > Questions About Treatment & Side Effects

how to increase BMD-bone mineral density?

(1/4) > >>

friskyguy:
hi all,

Had a DEXA scan a couple of years back and the results came back with a low "T " score and a diagnosis of osteopenia. Doctor changed me from Truvada to Epzicom (Kivezxa) as a result.

I know that maintaining optimal levels of VitD3 and calcium and exercise will assist lessen the decline but looking for some potential additional alternatives to help increase my "T" score by increasing bone density to prevent diminishing bone density as I age.

Has anyone else suffering from low BMD due to the meds or other reasons and can point to more effective remedies to increase bone density?

I read on-line that taking intravenously Zoledronate annually for 2 years lasts for more than 5 years and increases BMD (New Zealand study). Anyone taking these injections or other remedies that have worked?

thanks for any feedback
Frisky

buginme2:
Low bone density is common for people with HIV and it sounds like your doctor has started you on the proper course of treatment.

Switching off Truvada is often a first step.

Having your vitamin d levels checked and maintained is also a first step.

You should be doing weight bearing exercises (lift weights) regularly.  In addition to regular cardio.

If your numbers continue to decline or don't improve you may want to start an osteoporosis medication such as Boniva (or similar).  Some are one pill per month and some are by IV once a year or so.

Good luck.

aaware72:

--- Quote from: buginme2 on September 18, 2013, 03:47:31 PM ---
You should be doing weight bearing exercises (lift weights) regularly. 


--- End quote ---

This is very good information.  This is something all people can do to help keep bones strong.

eric48:

--- Quote from: aaware72 on September 18, 2013, 05:05:25 PM ---This is very good information.

--- End quote ---

It would be if it were substanciated. I am not saying it is wrong nor untrue, I am saying that the above post does not substanciate the claim.

Vit D3 supplementation: I take it in form of oral 100.000 UI 1/month dose. (Rx required)
Once my doc forgot to include in the prescription , so I had some 2000 UI pills at hand, I took them.
He said that 100.000 UI 1/month dose is more efficient than OTC daily

One should not forget that Vit D (same as B) is stored in a cumulative fashion in the liver, so over use is not recommended

See the following pointers

http://www.ncbi.nlm.nih.gov/pubmed/23611825

http://www.ncbi.nlm.nih.gov/pubmed/23072545

http://www.ncbi.nlm.nih.gov/pubmed/22293363

for further info

There is a clinical trial, if my memory is correct, that demonstrate superiority of 100.000 /monthly (oral)  vs ?000/daily oral , but could not find it

When supplementing, proper means of supplementation are required and monitoring as well.

I have not done much further research on this since my BMD came back OK and I am on Kivexa (aka Epzicom) which is not associated to BMD loss (at least not the the extend of TNF)

Currently at : (25OH-D2+D3) ....... 36 ng/ml

Calcium and Phosphate levels should be monitored as well

Hope this helps

eric

aaware72:

--- Quote from: eric48 on September 18, 2013, 06:58:12 PM ---It would be if it were substanciated. I am not saying it is wrong nor untrue, I am saying that the above post does not substanciate the claim.

Vit D3 supplementation: I take it in form of oral 100.000 UI 1/month dose. (Rx required)
Once my doc forgot to include in the prescription , so I had some 2000 UI pills at hand, I took them.
He said that 100.000 UI 1/month dose is more efficient than OTC daily

One should not forget that Vit D (same as B) is stored in a cumulative fashion in the liver, so over use is not recommended

See the following pointers

http://www.ncbi.nlm.nih.gov/pubmed/23611825

http://www.ncbi.nlm.nih.gov/pubmed/23072545

http://www.ncbi.nlm.nih.gov/pubmed/22293363

for further info

There is a clinical trial, if my memory is correct, that demonstrate superiority of 100.000 /monthly (oral)  vs ?000/daily oral , but could not find it

When supplementing, proper means of supplementation are required and monitoring as well.

I have not done much further research on this since my BMD came back OK and I am on Kivexa (aka Epzicom) which is not associated to BMD loss (at least not the the extend of TNF)

Currently at : (25OH-D2+D3) ....... 36 ng/ml

Calcium and Phosphate levels should be monitored as well

Hope this helps

eric

--- End quote ---

Hi Eric,

I was only referring to resistance training part of his post.  :)

"Abstract
Osteoporosis is a major public health problem that is characterized by low bone mass and increased susceptibility to fractures, primarily of the hip, spine, and wrist. It is estimated to cause 1.5 million fractures annually in the United States in people aged 50 yr and older. Physical activity, particularly weight-bearing exercise, is thought to provide the mechanical stimuli or "loading" important for the maintenance and improvement of bone health, whereas physical inactivity has been implicated in bone loss and its associated health costs. Both aerobic and resistance training exercise can provide weight-bearing stimulus to bone, yet research indicates that resistance training may have a more profound site specific effect than aerobic exercise. Over the past 10 years, nearly two dozen cross-sectional and longitudinal studies have shown a direct and positive relationship between the effects of resistance training and bone density. Conversely, a handful of other studies have reported little or no effect on bone density. However, these results may be partially attributable to the study design, intensity and duration of the exercise protocol, and the bone density measurement techniques used. High-intensity resistance training, in contrast to traditional pharmacological and nutritional approaches for improving bone health in older adults, has the added benefit of influencing multiple risk factors for osteoporosis including improved strength and balance and increased muscle mass."

http://www.ncbi.nlm.nih.gov/pubmed/9927006

Navigation

[0] Message Index

[#] Next page

Go to full version