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Author Topic: anorgasmia and insomnia from Stribild, Complera, or Truvada ???  (Read 1623 times)

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Offline witch

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  • Posts: 59
anorgasmia and insomnia from Stribild, Complera, or Truvada ???
« on: September 11, 2013, 11:55:56 PM »
Has anyone else experienced anorgasmia or insomnia from Stribild, Complera, or Truvada and how did you resolve the problem?

I was on Stribild for 4 months and the only side effects I had from it were insomnia (can't fall into a deep sleep) and anorgasmia (have nice erection but have trouble reaching orgasm). Two weeks ago, I switched to Complera, hoping to shake off the two side effects but they are still there.

The anorgasmia is partial. It consists of not feeling the usual pleasure when rubbing my penis. The pleasure eventually turns on but only 5 seconds before the orgasm. I had to fake orgasm a few times because I could not get there.

This happens with sexy partners and when I masturbate watching porn so I don't think the problem is psychological. Also, I was able to alleviate the problem by taking L-Histidine (converts to histamine which is necessary in the body for orgasm) 1 hour before masturbation and then I was able to feel some pleasure when masturbating, long before the orgasm. That partial reversal of the side effect seems to show that the problem is bio-chemical, not psychological.

Since I experience the partial anorgasmia from both Stribild and Complera, I think it should be caused by the common part of the two drugs which is known as Truvada (tenofovir and emtricitabine).

« Last Edit: September 11, 2013, 11:59:23 PM by witch »

Offline jkinatl2

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  • Posts: 6,007
  • Doo. Dah. Dipp-ity.
Re: anorgasmia and insomnia from Stribild, Complera, or Truvada ???
« Reply #1 on: September 12, 2013, 01:20:31 AM »
Has anyone else experienced anorgasmia or insomnia from Stribild, Complera, or Truvada and how did you resolve the problem?

I was on Stribild for 4 months and the only side effects I had from it were insomnia (can't fall into a deep sleep) and anorgasmia (have nice erection but have trouble reaching orgasm). Two weeks ago, I switched to Complera, hoping to shake off the two side effects but they are still there.

The anorgasmia is partial. It consists of not feeling the usual pleasure when rubbing my penis. The pleasure eventually turns on but only 5 seconds before the orgasm. I had to fake orgasm a few times because I could not get there.

This happens with sexy partners and when I masturbate watching porn so I don't think the problem is psychological. Also, I was able to alleviate the problem by taking L-Histidine (converts to histamine which is necessary in the body for orgasm) 1 hour before masturbation and then I was able to feel some pleasure when masturbating, long before the orgasm. That partial reversal of the side effect seems to show that the problem is bio-chemical, not psychological.

Since I experience the partial anorgasmia from both Stribild and Complera, I think it should be caused by the common part of the two drugs which is known as Truvada (tenofovir and emtricitabine).



Hello! Welcome to the forums!

Have you discussed this with your doctor? Perhaps finding another regimen that doesn't use the drugs in Trivada would help? I know it might make a bigger pill-per-day burden, but it looks like you might want to try anything at this point.

I know drugs like Cialis and Voagra can cause erections, but can also reduce sensation and make orgasm difficult (and extremely frustrating) to achieve.

Please let us know what you try, and what impact it has. I imagine many more people have issues like this than post about it, and I am glad you did. Human sexuality is a very important thing to many (I daresay most) people, and the loss of part of that function is decidedly a quality of life issue.


"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

Welcome Thread

Offline ad2san

  • Member
  • Posts: 186
Re: anorgasmia and insomnia from Stribild, Complera, or Truvada ???
« Reply #2 on: September 12, 2013, 02:42:56 AM »
Hello with and welcome to the forum.

You don't take any medication against depression?

Otherwise I agree with jkinatl2 and you should address the topic to your doc.


Cheers
Feb   2009 CD4 358 VL 2000 16%
May  2009 CD4 305 VL 3069  14% <---- Started TVD+ATZ/r
Jul  2009 CD4 512 VL <50   18%
Jul 2010 CD4 418 VL <50 24%                     
Switched to Kivexa (Epzicom) + Norvir + Reyataz (due to sleep problem)
Aug 2010 CD4 606 VL <50 25%
Apr 2011 CD4 523 UD 21%
Jul 2011 CD4 494 UD 23%
Switched to Kivexa (Epzicom) + Viramune XR (due to kidney problems)
January 2012 CD4 564 UD 31%
October 2012 CD4 684 UD 29%
January 2013 CD4 594 UD 26%
Switched to Kivexa (Epzicom) + Isentress due to BIG increase GammaGT
Feb 2013 CD4 699 UD 28%
May 2013 CD4 385 UD 28%
July 2013 CD4 CD4 636 UD 25%
Oct 2013 CD4 588 UD 39%

Offline witch

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  • Posts: 59
Re: anorgasmia and insomnia from Stribild, Complera, or Truvada ???
« Reply #3 on: September 12, 2013, 02:17:25 PM »
My Dr knows about all that. Unfortunately, most Dr don't know how to treat anorgasmia, which is the most common side effect of taking anti-depressants.

I used to take SSRI antidepressants in the past and they cause exactly the same chemical anorgasmia, that's why I do not take them anymore. My Psychiatrist Dr. could not suggest anything to alleviate it, except Viagra but Viagra does not resolve it. Viagra is more about erection not about reaching orgasm, although it may accelerate orgasm if all the required chemicals are in the body (that's my experience with Viagra when I didn't have anorgasmia).

The anorgasmia and insomnia started when I started taking Stribild so I am very sure it is causing it. I didn't have such problems before it. I already see some reports on here about Stribild causing insomnia so I am not imagining at least that part. Also, the anorgasmia is happening with or without Viagra so Viagra isn't causing it either.

I am asking if someone has experienced the same side effects from anti-hiv drugs before and how they were resolved? Perhaps by switching to some magical anti-hiv combo or by taking supplements/herbs/drugs?
« Last Edit: September 12, 2013, 02:35:51 PM by witch »

Offline weasel

  • Member
  • Posts: 1,667
Re: anorgasmia and insomnia from Stribild, Complera, or Truvada ???
« Reply #4 on: September 23, 2013, 02:05:27 PM »

  Hi Witch ,
                    Nice to meet you  :)

  Not sure about anything but the Truvada ,  I do not sleep without taking
 Trazadone .  I can go for a few days with little or no sleep . I prefer to take sleeping pills than being spacey .

   As for   anorgasmia ,   I have experienced   none with HIV drugs .

                                                                  Weasel
 

   
" Live and let Live "

Offline mikeyb39

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  • Posts: 922
Re: anorgasmia and insomnia from Stribild, Complera, or Truvada ???
« Reply #5 on: September 23, 2013, 06:26:44 PM »
I haven't heard of any anorgasmia issues with HIV medication, but with antidepressants hell yeah.  I took Effexor for a short period of time and suffered that, it was very freaky.  Needless to say I dropped that after about 3 weeks.

I will tell my little story about Effexor.  I went for two weeks with zero sexual desire at all, no erections.  One evening I decided to force myself to masterbate, it took about 30mins and all of a sudden I ejaculated and didn't even know I had done it.  scared the hell out of me.  stopped those pills that evening.

I know  TMI.
11/02/2010  cd4-251, vl-591000
12/09/2010  started Atripla
02/18/2011  cd4-425, vl-800
06/10/2011  cd4-447, vl-70
10/10/2011  cd4-666, vl-80
01/05/2012  swiched med (prezista,norvir ,isentress, )
02/10/2012  cd4-733, vl-UD  Viread removed
06/10/2012  cd4-614, vl-UD
12/14/2012  cd4-764, vl-UD
09/01/2013  cd4-785, vl-UD
03/06/2014. cd4- 1078, VL-UD

Offline oksikoko

  • Member
  • Posts: 680
  • Writing the congressman again
    • the treatment cascade
Re: anorgasmia and insomnia from Stribild, Complera, or Truvada ???
« Reply #6 on: September 23, 2013, 11:43:51 PM »
I know  TMI.

Pics or it didn't happen.
Code: [Select]
2013-10-03:                ☣ VL (=) undetectable ☣ CD4 (+) 1105
2013-05-23:                ☣ VL (=) undetectable ☣ CD4 (-) 945
2013-02-25:                ☣ VL (-) undetectable ☣ CD4 (+) 1123
2012-12-16: Enter Stribild
2012-11-20: HIV+           ☣ VL (→) 132,683      ☣ CD4 (→) 920
2012-04-01: HIV-
Dates in this signature file conform to ISO 8601. ;-)

 


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