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Author Topic: What should I do after vomiting?  (Read 1548 times)

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Offline hiv_positive_BG

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What should I do after vomiting?
« on: July 18, 2013, 12:36:47 AM »
Hello, I take Norvir, Reyataz, Kivexa daily, and those should be endeavored with food. But just 3-4 hours ago I suffered terrible vomiting, probably due to bad food. Currently I feel pretty weak and my belly is 100% empty. What should I do with my daily dose, as the time to take it has come?

Offline jkinatl2

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Re: What should I do after vomiting?
« Reply #1 on: July 18, 2013, 12:44:27 AM »
If you can't eat, and might vomit, and are otherwise compliant with your dosing, then I would absolutely skip this dose and hope tha tyour next dose will arrive to find you in better spirits.

A missed dose now and then is not the end of the world.

"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

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Offline hiv_positive_BG

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Re: What should I do after vomiting?
« Reply #2 on: July 18, 2013, 12:46:24 AM »
OK, thanks a lot chap. Yes, I am very strict, and for some eight months that would be the first dose skipped.

Offline LiveWithIt

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Re: What should I do after vomiting?
« Reply #3 on: July 18, 2013, 12:57:00 AM »
Can you keep anything down?  If so have a piece of bread or a cracker or two and take your meds.
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Offline jkinatl2

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Re: What should I do after vomiting?
« Reply #4 on: July 18, 2013, 12:57:55 AM »
OK, thanks a lot chap. Yes, I am very strict, and for some eight months that would be the first dose skipped.

It is great that you are diligent about your dosing! But if you are sick to your stomach, better to skip a dose than force yourself to take it, perhaps throw up a portion of it, and be half-dosed. THAT is when resistance can emerge. I really hope you feel better soon. Throwing up is the absolute worst.

"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

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Offline jkinatl2

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Re: What should I do after vomiting?
« Reply #5 on: July 18, 2013, 01:41:42 AM »
Can you keep anything down?  If so have a piece of bread or a cracker or two and take your meds.

Disagree. Better to miss a dose than to barf up half a dose. It's the half-dosing you need to worry about, not the occasional missed dose.

"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

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Offline Ann

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Re: What should I do after vomiting?
« Reply #6 on: July 18, 2013, 05:53:00 AM »
Disagree. Better to miss a dose than to barf up half a dose. It's the half-dosing you need to worry about, not the occasional missed dose.



Surely a one-off, barfed-up half dose is no worse than a one-off completely missed dose? I'm not following your logic.

Besides, unless you're barfing up whole tablets that you can actually see and identify in your barf, then chances are good that they've already been pretty much absorbed or moved deeper into the gut before you've barfed.
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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline jkinatl2

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Re: What should I do after vomiting?
« Reply #7 on: July 18, 2013, 02:14:33 PM »
Surely a one-off, barfed-up half dose is no worse than a one-off completely missed dose? I'm not following your logic.

Besides, unless you're barfing up whole tablets that you can actually see and identify in your barf, then chances are good that they've already been pretty much absorbed or moved deeper into the gut before you've barfed.

I'm pretty sure is six of one, half dozen of the other. But given the choice, I would rather skip the dose than go through the barfing process (which would, I imagine, include the requisite meal that one takes with the drugs).

I recall taking first gen Viracept - or rather, attempting to take them. Huge, uncoated blue bastards would stick in my throat and I would either barf, or force myself to chug water until they dissolved (kinda) in my throat, leaving it burned for hours.

I did read somewhere that, if you keep your stuff down for twenty minutes, you have given it time to dissolve. But like I said, it's not just the whales, it's the water (to quote Star Trek IV).




"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

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Offline Ann

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Re: What should I do after vomiting?
« Reply #8 on: July 18, 2013, 02:27:43 PM »
I'm pretty sure is six of one, half dozen of the other. But given the choice, I would rather skip the dose than go through the barfing process (which would, I imagine, include the requisite meal that one takes with the drugs).

I recall taking first gen Viracept - or rather, attempting to take them. Huge, uncoated blue bastards would stick in my throat and I would either barf, or force myself to chug water until they dissolved (kinda) in my throat, leaving it burned for hours.

I did read somewhere that, if you keep your stuff down for twenty minutes, you have given it time to dissolve. But like I said, it's not just the whales, it's the water (to quote Star Trek IV).

OK, I get your logic now. Nobody likes to puke.


What confused me was your prior post about developing resistance - I should have also quoted that post I 'spose.

It is great that you are diligent about your dosing! But if you are sick to your stomach, better to skip a dose than force yourself to take it, perhaps throw up a portion of it, and be half-dosed. THAT is when resistance can emerge. I really hope you feel better soon. Throwing up is the absolute worst.



And yeah, I remember reading in several places where you're ok if you've had at least twenty minutes between taking your meds and puking. Hell if I can remember where I've read it though.
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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline buginme2

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Re: What should I do after vomiting?
« Reply #9 on: July 18, 2013, 03:30:36 PM »
This does shed light on the fact that there are no treatment options currently available for someone unable to take medications orally. 

Fuzeon is injectable however, one med does not make for an effective HIV therapy.

They are currently testing an injectable rilpivrine and the new integrate inhibitor (forgot its name).  Hopefully they will have success.  Otherwise, should anyone be laid up and unable to take your meds orally you could be up a creek.

Offline Jmarksto

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Re: What should I do after vomiting?
« Reply #10 on: July 18, 2013, 03:45:56 PM »
This does shed light on the fact that there are no treatment options currently available for someone unable to take medications orally. 

Fuzeon is injectable however, one med does not make for an effective HIV therapy.

They are currently testing an injectable rilpivrine and the new integrate inhibitor (forgot its name).  Hopefully they will have success.  Otherwise, should anyone be laid up and unable to take your meds orally you could be up a creek.

Here is the link to that trial info:

http://www.aidsmeds.com/articles/nanosupension_longacting_1667_24248.shtml

My question is that they are testing these two meds together, but don't we need three meds?  Does anyone know if these two together would be sufficient, or if there is a third that could be combined for a monthly injection?
03/15/12 Negative
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08/06/12 CD4 816/38%   VL 49,300
08/20/12 Started Complera
11/06/12 CD4   819/41% VL 38
02/11/13 CD4   935/41% VL UD
06/06/13 CD4   816/41% VL UD
10/28/13 CD4 1131/45%  VL 25
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07/09/14 CD4 1004/39%   VL UD

Offline jkinatl2

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Re: What should I do after vomiting?
« Reply #11 on: July 18, 2013, 03:50:13 PM »
I absolutely didn't mean to imply that one half-dose (or one barfed dose) would lead to resistance, but a few weeks' worth of them stands that chance.

And I share your concern, Buginme, about the dearth of options for those unable to take medications orally. There really isn't much wriggle room in that department, is there?

"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

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Offline newt

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Re: What should I do after vomiting?
« Reply #12 on: July 19, 2013, 04:37:22 AM »
On this combination, if you vomit more than 2 hrs after taking your meds then they are all in your blood system already.

Before that, possibly not in totality.

I agree with JK that missing a day cos of chucking will be no big deal. It's intermittent low dosing/no dosing that leads to resistance.

- matt
"The object is to be a well patient, not a good patient"

Offline hiv_positive_BG

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Re: What should I do after vomiting?
« Reply #13 on: July 22, 2013, 09:51:11 AM »
Thanks a lot for your answers... I was late an hour and a half, but suddenly felt better and took my "dose"... In the same context, I wonder one more thing: how long after taking the meds it's safe to take an enema? I read suggestions from 20 minutes to two hours, that after such period the meds are absorbed in my blood, or?

Offline Ann

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Re: What should I do after vomiting?
« Reply #14 on: July 22, 2013, 10:58:04 AM »
Thanks a lot for your answers... I was late an hour and a half, but suddenly felt better and took my "dose"... In the same context, I wonder one more thing: how long after taking the meds it's safe to take an enema? I read suggestions from 20 minutes to two hours, that after such period the meds are absorbed in my blood, or?

Unless the meds you take are in the form of suppositories, I can't see an enema making any difference to when you take your meds by mouth. Opposite ends of the digestive system on most people.
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

 


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