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Sign-On Letter to Gilead

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oksikoko:
Signed, and I hope they listen. I've read about TAF, but I didn't know it would work for people who have mutations resistant to TDF - assuming I read that correctly. That's good news. I have questions maybe one of you can answer...

They mentioned combining TAF with cobicistat, emtricitabine and elvitegravir in a once-per-day. Does this mean that Gilead would produce two formulations of Stribild, one with TAF and one with TDF or will the TAF phase the TDF out completely? Would this happen overnight, so to speak? I guess what I'm really asking is, assuming that I'm still taking Stribild when TAF comes out, would I one day simply start getting the new formulation or would I keep the current formulation until my entire regimen changed at some point in the future? Is there a precedent for replacing one drug of a combo (not necessarily in one pill) with a new-and-improved version like this?  Seems kinda complicated to just swap out a drug like that, so I'm assuming it'll be a more complex switchover than just <poof> TAF.

Thanks for any info on how this sort of thing works.

Lee

Piscean:
Signed. Thanks for posting the link.

buginme2:

--- Quote from: oksikoko on June 16, 2013, 04:52:54 PM ---Signed, and I hope they listen. I've read about TAF, but I didn't know it would work for people who have mutations resistant to TDF - assuming I read that correctly. That's good news. I have questions maybe one of you can answer...

They mentioned combining TAF with cobicistat, emtricitabine and elvitegravir in a once-per-day. Does this mean that Gilead would produce two formulations of Stribild, one with TAF and one with TDF or will the TAF phase the TDF out completely? Would this happen overnight, so to speak? I guess what I'm really asking is, assuming that I'm still taking Stribild when TAF comes out, would I one day simply start getting the new formulation or would I keep the current formulation until my entire regimen changed at some point in the future? Is there a precedent for replacing one drug of a combo (not necessarily in one pill) with a new-and-improved version like this?  Seems kinda complicated to just swap out a drug like that, so I'm assuming it'll be a more complex switchover than just <poof> TAF.

Thanks for any info on how this sort of thing works.

Lee

--- End quote ---

The new quad2 formulation (the one with taf) will prob just take the place of the old quad formulation (with tdf). 

Ann:

--- Quote from: buginme2 on June 16, 2013, 04:26:15 PM ---money

--- End quote ---

Gilead

Signed - and shared.

mitch777:

--- Quote from: Ann on June 17, 2013, 07:17:30 AM ---Gilead

Signed - and shared.

--- End quote ---

Ann, when clicking on your link it comes up saying "the content is unavailable in your country".
Just thought you might want to know.

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