Meds, Mind, Body & Benefits > Questions About Treatment & Side Effects

Can I take Atripla three-four hours earlier than usual time for a couple days?


Hi folks,

I have been on Atripla for around 6 months now (never missed a dose :D). I generally take it at around midnight every night before going to bed. And I get up at 8 am most mornings, refreshed and ready to take on the day! :D Some nights when I am out with my friends, I have come back home at 4 am and taken my Atripla.  This regimen has suited me fine up until now.

However, I have a major shift in my job timings coming up for a few days which would require me to wake up like at 4 am or 5 am for a couple of days, requiring me to sleep by 9 pm the previous night.

Can I take my Atripla between 8 pm to 9 pm for a few days (instead of usual midnight time) since I require to get up between 4 am and 5 am the next day? Would taking my drug 3-4 hours earlier than my usual timing affect its effectiveness or cause any undue side effects? Would I be able to switch back to my regular midnight time after these few days or would i be stuck with the new timings forever?

I did try to take my Atripla at my usual midnight time and get up like at 5 am the next morning, but my head was spinning so fast as if I have taken my drug just an hour back. I know of CNS side effects of EFV but can then still affect me after 5 hours?? So I went back to sleep, got up at my regular 8 am and was fine. So this experiment obviously did not work.

Please advise.

Thanks to all of you in advance.


Hi Gaynpositive,
it's perfectly fine if you miss your dose timing from time to time.  As long as you take it everyday and are not missing it completely multiple times a week.  My doctor tells me that its ok not to be exact everyday, just make sure you take them everyday.

I don't take Atripla anymore, but they are all the same.  I don't take my pills exactly the same time, sometimes it depends on my daily schedule i may take it 3 hours before or 3 hours late from time to time

In short, yes - matt


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