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Author Topic: Treatment in 2020.  (Read 1742 times)

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Offline young89

  • Member
  • Posts: 8
Treatment in 2020.
« on: May 03, 2013, 12:23:08 AM »
Just an optimistic thread.

Do you think by 2020, any advances will have been made in the treatment of HIV?

thoughts ?

Offline elf

  • Member
  • Posts: 582
Re: Treatment in 2020.
« Reply #1 on: May 04, 2013, 04:17:09 PM »
More expensive variants of the same meds we have, to boost big pharma sales.
Let's have a Kiki!

Offline Elkan

  • Member
  • Posts: 33
Re: Treatment in 2020.
« Reply #2 on: May 04, 2013, 05:25:04 PM »
lol....
i think the research has always shown something promising but yet fails us every single time. so i have decided not to place my hopes on them :(

Offline Joe K

  • Global Moderator
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  • Posts: 3,173
  • 30 Years Poz
Re: Treatment in 2020.
« Reply #3 on: May 04, 2013, 05:35:37 PM »
lol....
i think the research has always shown something promising but yet fails us every single time. so i have decided not to place my hopes on them :(

How exactly do you define "progress"?  At one time, I took 32 pills, each and every day, just to treat my HIV.  I now take three to do the same thing.  If HIV drug research "fails us every single time", where exactly did we get all the new classes of drugs?

Joe
Life is what happens, when you are busy making other plans.

Though you may be only one person in the entire world, to one person, you may be the entire world.

I wish to become half the man, that my dog thinks I am.

Remember me with simple acts of kindness and I will live forever.

Offline JazJon

  • Member
  • Posts: 94
Re: Treatment in 2020.
« Reply #4 on: May 04, 2013, 05:46:31 PM »
I think HIV will have a cure or functional cure by 2020.  (either Gene Transfer/Stem Cell, or Latency Wake-up and kill methods) We'll then have to deal with the aftermath I posted about here:

What would the world be like AFTER HIV is cured? (The good, bad & ugly) http://forums.poz.com/index.php?topic=48458.0

Offline mecch

  • Member
  • Posts: 10,702
  • red pill? or blue pill?
Re: Treatment in 2020.
« Reply #5 on: May 04, 2013, 05:56:54 PM »


« Last Edit: May 04, 2013, 06:00:17 PM by mecch »
ďFrom each, according to his ability; to each, according to his needĒ 1875 K Marx

Offline buginme2

  • Member
  • Posts: 2,738
  • Certified Life Coach
Re: Treatment in 2020.
« Reply #6 on: May 04, 2013, 08:03:34 PM »
2020 isn't that far away, what 6 1/2 years give or take.   So I do not expect a panacea of change.  Change happens incrementally, sure sometimes you hit a breakthrough but most change happens in incremental steps.

We will probably have a few more single tablet options.  We may even have one (maybe two) options that require once a week or even once a month dosing.  Kinda like how old ladies take a Boniva pill once a month.

I don't expect a cure (but I'm a pessimist.  They will be closer sure.  But the FDA is going to make fucking damn sure that any new treatment is safe and effective before they allow a new wide scale treatment when there is already an effective treatment available...think about it.  And that could take many years to demonstrate with many clinical trials before any new type of treatment/cure attempt is approved).
"All I need are some tasty waves, a cool buzz, and I'm fine."

http://www.youtube.com/watch?v=6e0gcEC1TWE

Offline freewillie99

  • Member
  • Posts: 303
Re: Treatment in 2020.
« Reply #7 on: May 04, 2013, 08:53:11 PM »
What about in the year 2525?
Beware Romanians bearing strange gifts

Offline Elkan

  • Member
  • Posts: 33
Re: Treatment in 2020.
« Reply #8 on: May 04, 2013, 10:35:11 PM »
How exactly do you define "progress"?  At one time, I took 32 pills, each and every day, just to treat my HIV.  I now take three to do the same thing.  If HIV drug research "fails us every single time", where exactly did we get all the new classes of drugs?

Joe

I am truly sorry for my word. What I meant was to cure HIV entirely.
the treatment has definitely improved a lot over years. We all hope the treatment's improving day by day to lengthen our lives with less harm :) hope the day will come sooner.

Offline Basquo

  • Member
  • Posts: 3,235
Re: Treatment in 2020.
« Reply #9 on: May 04, 2013, 10:56:34 PM »
I really hope there is some kind of major advancement in treatment soon-ish. Like in the next couple of years. I was truly miserable when I was doing the last clinical trial/LTNP study visit in Boston in January, but I will do it again and again as long as they ask me and as lonng as my job will let me take the time off. I've lost too many friends to be complacent now.

Online Miss Philicia

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  • Posts: 23,555
  • celebrity poster, faker & poser
Re: Treatment in 2020.
« Reply #10 on: May 04, 2013, 11:22:11 PM »
I hope all the latest drugs are shown to give us all severe lipoatrophy
"Iíve slept with enough men to know that Iím not gay"

Offline Jeff G

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  • How am I doing Beren ?
Re: Treatment in 2020.
« Reply #11 on: May 04, 2013, 11:30:25 PM »
I think we will use jet packs to fly to the pharmacy .

Offline buginme2

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  • Posts: 2,738
  • Certified Life Coach
Re: Treatment in 2020.
« Reply #12 on: May 04, 2013, 11:49:34 PM »
This is all really kind of sad.  ONE article written by an over zealous newspaper reporter gets picked up by every lazy "news" service has gotten a lot of people hopes up very high. 

There are going to be a lot of unhappy people "within months"

I predict.
"All I need are some tasty waves, a cool buzz, and I'm fine."

http://www.youtube.com/watch?v=6e0gcEC1TWE

Offline mecch

  • Member
  • Posts: 10,702
  • red pill? or blue pill?
Re: Treatment in 2020.
« Reply #13 on: May 05, 2013, 12:00:48 AM »
I hope all the latest drugs are shown to give us all severe lipoatrophy
:o ??? :-[ :-\ :(
ďFrom each, according to his ability; to each, according to his needĒ 1875 K Marx

Offline Elkan

  • Member
  • Posts: 33
Re: Treatment in 2020.
« Reply #14 on: May 05, 2013, 01:08:24 AM »
This is all really kind of sad.  ONE article written by an over zealous newspaper reporter gets picked up by every lazy "news" service has gotten a lot of people hopes up very high. 

There are going to be a lot of unhappy people "within months"

I predict.


sadly, I believe so too.
but let's still hope there will be some kind of breakthrough in months time, just don't put that much of hope into it maybe.

Online Miss Philicia

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  • celebrity poster, faker & poser
Re: Treatment in 2020.
« Reply #15 on: May 05, 2013, 01:15:20 AM »
Few of you cared about a cure a year or two ago. Funny how that works.
"Iíve slept with enough men to know that Iím not gay"

Offline JazJon

  • Member
  • Posts: 94
Re: Treatment in 2020.
« Reply #16 on: May 05, 2013, 03:04:23 AM »
Few of you cared about a cure a year or two ago. Funny how that works.

Calimune's Gene Transfer has huge potential.
http://forums.poz.com/index.php?topic=46455.0

Offline jkinatl2

  • Member
  • Posts: 6,007
  • Doo. Dah. Dipp-ity.
Re: Treatment in 2020.
« Reply #17 on: May 05, 2013, 03:33:20 AM »
There are no fewer than three trials underway to distribute HIV meds once every six months via I.V. which will, for people who have an UD VL, provide a relief from any other medication. This much I know because I am part of that trial. If and when they decide I qualify and they proceed in the Atlanta area, I will keep you guys informed.

Thing is, cynics aside, there is no reason that, by 2020, what we conceive as a "functional cure" won't be realized.

"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

Welcome Thread

Offline JazJon

  • Member
  • Posts: 94
Re: Treatment in 2020.
« Reply #18 on: May 05, 2013, 03:56:30 AM »
There are no fewer than three trials underway to distribute HIV meds once every six months via I.V. which will, for people who have an UD VL, provide a relief from any other medication. This much I know because I am part of that trial. If and when they decide I qualify and they proceed in the Atlanta area, I will keep you guys informed.

Thing is, cynics aside, there is no reason that, by 2020, what we conceive as a "functional cure" won't be realized.

I was wondering if they would finally have a clinical trial for the long lasting ART shot/I.V. treatment.  I remember hearing about it a long time ago and then nothing.    Is it for treatment naive (never been on meds) or for someone already UD on meds.   What's the link so I can check out the qualifications and read more about it? (both poz forum and the study itself)

Offline Jmarksto

  • Member
  • Posts: 388
Re: Treatment in 2020.
« Reply #19 on: May 05, 2013, 07:53:14 AM »
2020 isn't that far away, what 6 1/2 years give or take.   So I do not expect a panacea of change.  Change happens incrementally, sure sometimes you hit a breakthrough but most change happens in incremental steps.

We will probably have a few more single tablet options.  We may even have one (maybe two) options that require once a week or even once a month dosing.  Kinda like how old ladies take a Boniva pill once a month.

I don't expect a cure (but I'm a pessimist.  They will be closer sure.  But the FDA is going to make fucking damn sure that any new treatment is safe and effective before they allow a new wide scale treatment when there is already an effective treatment available...think about it.  And that could take many years to demonstrate with many clinical trials before any new type of treatment/cure attempt is approved).

The data supports Bug's line of thinking.  The best way to see what the future holds is to see where the money is being spent today. Based on the Treatment Action Group's Global Investments in HIV Treatment Research and Development in 2010 and 2011, the $2.5 billion/year of funding is spent as follows:

Drugs                                                51.8%
Basic Science                                     31.7%
Operational and Implementation Science  13.4%
Applied/Infrastructure/Unspecified          1.6%
Therapeutic Vaccines                           0.8%

I think in five years we will have much better drugs, a much better understanding of the basic science, and a realistic expected timeline towards a vaccine or cure.  I think we will also see a blurring of the definition between treatment drugs and a vaccine -- for example, would a once per year treatment (that worked as both treatment and PREP) be considered a vaccine?

Sadly, there is no funding for jet packs to get us to the pharmacy...

JM
« Last Edit: May 05, 2013, 08:23:18 AM by Jmarksto »
03/15/12 Negative
06/15/12 Positive
07/11/12 CD4 790          VL 4,000
08/06/12 CD4 816/38%   VL 49,300
08/20/12 Started Complera
11/06/12 CD4   819/41% VL 38
02/11/13 CD4   935/41% VL UD
06/06/13 CD4   816/41% VL UD
10/28/13 CD4 1131/45%  VL 25
02/25/14 CD4   792/37%  VL UD

Offline bocker3

  • Member
  • Posts: 3,253
  • You gotta enjoy life......
Re: Treatment in 2020.
« Reply #20 on: May 05, 2013, 10:02:57 AM »
Funny how the future always seems to surprise us when it becomes the present. 
I mean where are all the flying cars we were promised we'd have by now???
Who would have predicted in 2006, that 20% of the states would have legal same-sex marriages by 2013???

My point -- predicting the future is best left to those with actual crystal balls. 
Hope is a great thing, so long as folks don't begin believing the hoped for timelines and outcomes.

Mike
Atripla - Started 12/05
Reyataz/Norvir - Added 6/06
Labs - Pre-Meds
Sep05 T=350/25% VL98,559
Nov05 288/18%  47,564
Current Labs
May2013 691/31% <20

 


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