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Author Topic: question about generic 3 in 1 pill: mylan TDF/3TC/EFV  (Read 2477 times)

0 Members and 1 Guest are viewing this topic.

Offline butpoz

  • Member
  • Posts: 27
question about generic 3 in 1 pill: mylan TDF/3TC/EFV
« on: April 13, 2013, 07:27:04 AM »
Hi all,

I have questions about generic 3 in 1 pill produced by company MyLan.com that would like to hear from you guys if possible.

- the pill is free, given by government in my country.
- its content is TDF: 300mg, EFV: 600mg, 3TC: 300mg.
- I have been on it for about 1 year. Result from last oct test is: UD, CD4=550 (increased from 350 about 1 year ago). I take it in the morning, no side effect.

Recently I heard from a friend who is also a doctor that 3TC may not be good enough for taking once per day due to its half life is short. His recommendation is changing to a combination that has TFC instead of 3TC.

So my questions are:
- is there anyone here taking same combination as mine and what is the result?
- what do you think about my friend's comment above?

thanks in advanced,
butpoz

Offline Anqueetas

  • Member
  • Posts: 116
Re: question about generic 3 in 1 pill: mylan TDF/3TC/EFV
« Reply #1 on: April 25, 2013, 07:26:03 AM »
Are you confuse TFC with FTC (Emtricitabine)?

Lamivudine 3TC is an old NRTI that most developed country don't use anymore, its get replace by FTC which is more potent and have less side effect.
ARS, hospitalized for very high fever-July 2011
diagnosed HIV positive - October 16 2011
CD4 460 19.5% VL 49000 - late October 2011
CD4 625 19.5% VL 50030 - January 2012
CD4 369 19% VL 69000 - March 2012
Start Sustiva+ Truvada - April 17 2012
CD4 524 24.5% VL UD - August 22 2012
Switch to Nevirapine+Truvada
CD4 490 26% VL UD - November 2012
CD4 539 29% VL UD - February 2013
CD4 621 28% VL UD - May 2013

Offline Pozdudesh

  • Member
  • Posts: 13
Re: question about generic 3 in 1 pill: mylan TDF/3TC/EFV
« Reply #2 on: April 30, 2013, 11:16:55 AM »
Currently first line treatment in china is EFV+3TC+TDF,I also heard people in south Africa is having the same combination...
As an Chinese citizen , I decided put myself on EFV+FTC+TDF..I got FTC+TDF in Thailand ...as the thai doctor said ,FTC stays bit of longer than 3TC in the blood,and in long term , FTC have lower risk raise side effect to liver and kidney...But these two combination dosent have significant difference ...I know people in china took 3TC is doing fine...
Best
Chris

Offline Valmont

  • Member
  • Posts: 330
Re: question about generic 3 in 1 pill: mylan TDF/3TC/EFV
« Reply #3 on: April 30, 2013, 02:33:24 PM »
Hey, I receive FTC - TDF - EFV from the same laboratory (Mylan), Iīm in Ecuador, my hospital change regularly our pills brand, sometimes I receive triterapia in one pill, sometimes in two (in this case, Efavirez is separated), I also got VIRADAY by my own.

Never noticed any difference between these differents solutions (all produce this typical dizzyness which comes with EFV), my numbers are great.  I think you should not be worried with the brand.

About 3TC, no idea, I heard that they were using this combo in Colombia, but not sure...

There are some info form OMS (WHO?), if you can read spanish (sorry, I havenīt found it in English) in the following link, check page 40.  3TC - EFV - TDF is described as a first line treatment and efficient.
http://es.scribd.com/doc/74386369/Tratamiento-Antiretroviral-VIH
Apr 2011: Diagnotized
Jun 2011: CD4: 504  VL: 176.000
Dic 2011: CD4: 714  VL: 95.000
May 2012: CD4: 395 VL: 67.000
Jun 2012: CD4: 367
Agu 2012: Starting Emtricitabine 200 mg / Tenofovir 300 mg and Efavirenz 600 mg (2 pills) different brands or VIRADAY/ATRIPLA/Mylan....
Sep 2012: VL: 138
Dic 2012: CD4: 708 VL: <34  %CD4: 32%
Jan 2013: CD4: 707 VL: <20
May 2013: CD4: 945 VL: <34 %CD4: 33%
Agu 2013: CD4: 636 VL: <34 %CD4: 50%
Dic 2013: Latent TB, started Isoniazid

Offline newt

  • Member
  • Posts: 3,877
  • the one and original newt
Re: question about generic 3 in 1 pill: mylan TDF/3TC/EFV
« Reply #4 on: April 30, 2013, 03:53:58 PM »
3TC is fine once a day, so what is the issue? It's commonly used in England (with abacavir mainly)

- matt
"The object is to be a well patient, not a good patient"

Offline JAYSONWOO

  • Member
  • Posts: 3
Re: question about generic 3 in 1 pill: mylan TDF/3TC/EFV
« Reply #5 on: June 21, 2013, 05:08:56 AM »
hey!Pozdudesh  I am a chinese who got the EFV+3TC+TDF from chinese doctor , but i have saw your comment about 3TC and FTC in Thailand , I want to know some information about how to buy FTC in Thailand,and some informamtion if i go to see a doctor in Thailand , How can we contact ? pls help me ... thank you so much

Jaysonwoo

Offline JAYSONWOO

  • Member
  • Posts: 3
Re: question about generic 3 in 1 pill: mylan TDF/3TC/EFV
« Reply #6 on: June 21, 2013, 10:52:00 PM »
Currently first line treatment in china is EFV+3TC+TDF,I also heard people in south Africa is having the same combination...
As an Chinese citizen , I decided put myself on EFV+FTC+TDF..I got FTC+TDF in Thailand ...as the thai doctor said ,FTC stays bit of longer than 3TC in the blood,and in long term , FTC have lower risk raise side effect to liver and kidney...But these two combination dosent have significant difference ...I know people in china took 3TC is doing fine...
Best
Chris
hey!Pozdudesh  I am a chinese who got the EFV+3TC+TDF from chinese doctor , but i have saw your comment about 3TC and FTC in Thailand , I want to know some information about how to buy FTC in Thailand,and some informamtion if i go to see a doctor in Thailand , How can we contact ? pls help me ... thank you so much

Jaysonwoo

 


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