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Author Topic: Viramune/Truvada - Skin reaction  (Read 1499 times)

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Offline Common_ground

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  • Posts: 288
Viramune/Truvada - Skin reaction
« on: March 21, 2013, 11:00:11 AM »
So Im on my 3rd day of this new combo, doing 2 weeks with half dose,previously Stocrin and Truvada did a good job getting me to UD and keeping me there but I rarely had a good nites sleep and I was also anxious and out of it with because of the efavirenz I assume.

Things are now way better with the Viramune/Truvada, it feels like Im back to my old self, no irrational thoughts and depression, my head is clear and I can think straight. Best of all is that I can sleep well without crazy dreams and not wake up in the middle of the nite.

However, I have some kind of skin reaction, I dont know if its really a rash, but its a little read and the skin looks a bit strange  :-\. I think I am the only one noticing this, I would consider it very mild and if I didnt point it out people wouldnt notice even sitting next to me. I can see it on two fingers and my feet.

It doesnt hurt and its not swollen. Cant bear to take the Stocrin again now that I know how much better I feel on this combo.

So after reading up I understand this is fairly common, but does it mean that Im doomed to give up the Viramune? Even my liver tests shows nothing irregular?

I know there are many more options but where I reside we dont have access to all new meds and also I pay out of pocket, so things like Isentress, Prezista, Intelence is a unfortunately a no go.

Thanks for reading.
2011 May - Neg.
2012 June CD4:205, 16% VL:2676 Start Truvada/Stocrin
2012 July  CD4:234, 18% VL:88
2012 Sep  CD4:238, 17% VL:UD
2013 Feb  CD4:257, 24% VL:UD -viramune/truvada
2013 May CD4:276, 26% VL:UD

Offline buginme2

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Re: Viramune/Truvada - Skin reaction
« Reply #1 on: March 21, 2013, 12:17:58 PM »


Things are now way better with the Viramune/Truvada, it feels like Im back to my old self, no irrational thoughts and depression, my head is clear and I can think straight. Best of all is that I can sleep well without crazy dreams and not wake up in the middle of the nite.


So after reading up I understand this is fairly common, but does it mean that Im doomed to give up the Viramune?

Good to hear your doing so well.  I'm switching off Atripla (Sustiva) in a few months also.  It sounds like the change has gone pretty well. 

I don't think your doomed at all.  Give it time.  A mild rash is common in the beginning.  I remember when I started Atripla I got a rash.  It went away.  Your probably just getting used to the new medication.  Your doc is monitoring your liver tests and that's important with Viramune. 

Good luck, sounds like your you'll be good.

Offline Ann

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  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: Viramune/Truvada - Skin reaction
« Reply #2 on: March 21, 2013, 12:29:01 PM »
CG, have you read the information page on Viramune in the Treatments section of this website yet?

In the What is known about side effects? section of the Viramune page, it says the following:

The most common side effect of Viramune is skin rash.

In a
small number of patients, rash has been serious and resulted in death.

Therefore, if you develop a rash with any of the following symptoms, call your doctor immediately:

general ill feeling,

*fever,

*muscle or joint aches,

*blisters,

*mouth sores,

*conjunctivitis (inflammation of the inner surface of the eyelids),

*swelling of the face,

tiredness.


When it mentions tiredness above, it's talking about extreme tiredness and lethargy, as in not even being able to get out of bed. It's not talking about general tiredness. Everyone gets that.

The symptoms I marked with "*" are the ones you mainly need to watch out for - and the muscle and joint aches are the extreme all-over type like what you get when you have the flu. The fever that can accompany this serious reaction is typically quite a high one, like over 102F (39C).

It does not sound at all like you're getting the serious rash. The rash you are experiencing - if it even has anything to do with Viramune at all - will likely go away within a few days.

If the rash gets worse, get in touch with your doctor. He or she will probably prescribe for you an antihistamine type drug like Benadryl (diphenhydramine) to deal with the itchiness.

And of course if you develop a high fever and/or facial swelling and/or blistering, get to your doctor ASAP.

I really do not think you're having anything other than a MILD run-of-the-mill rash reaction that will go away once your body is accustomed to the med. So don't worry about it so much. 

Good luck and let us know how it goes.
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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline Common_ground

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  • Posts: 288
Re: Viramune/Truvada - Skin reaction
« Reply #3 on: March 26, 2013, 02:29:37 AM »
quick update

The rash I experienced after a few days has gradually subsided and is now almost completely gone. I have taken an antihistamine for a few days cant really tell if that had any effect or not. Continue to sleep very well, loads more energy during the day and mentally I feel great.
Just hoping liver tests next week shows up ok so I can go on the full dose.

Feels I got a new lease on life.
2011 May - Neg.
2012 June CD4:205, 16% VL:2676 Start Truvada/Stocrin
2012 July  CD4:234, 18% VL:88
2012 Sep  CD4:238, 17% VL:UD
2013 Feb  CD4:257, 24% VL:UD -viramune/truvada
2013 May CD4:276, 26% VL:UD

Offline Common_ground

  • Member
  • Posts: 288
Re: Viramune/Truvada - Skin reaction
« Reply #4 on: April 02, 2013, 08:27:59 AM »
So 2 weeks on this new combo. Checked liver and the test came out good, even better than last drawing with the previous combo, cant remember all the numbers but ALT was 19. Going on the full dose from here on.
2011 May - Neg.
2012 June CD4:205, 16% VL:2676 Start Truvada/Stocrin
2012 July  CD4:234, 18% VL:88
2012 Sep  CD4:238, 17% VL:UD
2013 Feb  CD4:257, 24% VL:UD -viramune/truvada
2013 May CD4:276, 26% VL:UD

Offline Ann

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  • Member
  • Posts: 28,140
  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: Viramune/Truvada - Skin reaction
« Reply #5 on: April 02, 2013, 08:49:36 AM »
Thanks for the updates. It sounds like you're doing great! :)
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline northernguy

  • Member
  • Posts: 1,347
Re: Viramune/Truvada - Skin reaction
« Reply #6 on: April 06, 2013, 09:42:43 PM »
Glad to hear you're doing well.  I made the same switch two years ago and never regretted it. 
Apr 28/06 cd4 600 vl 10,600 cd% 25
Nov 8/09 cd4 510 vl 49,5000 cd% 16
Jan 16/10 cd4 660 vl 54,309 cd% 16
Feb 17/10 Started Atripla
Mar 7/10 cd4 710 vl 1,076 cd% 21
Apr 18/10 cd4 920 vl 268 cd% 28
Jun 19/10 cd4 450 vl 60 cd% 25
Aug 15/10 cd4 680 vl 205 cd% 27
Apr 3/11 cd4 780 vl <40 cd% 30
Jul 17/11 cd4 960 vl <40 cd%33
April 15/12 cd4 1,010 vl <40 cd% 39
April 20/12 Switched to Viramune + Truvada
Aug 2/12 cd4 1040, vl <40, cd% 38
Oct 19 cd4 1,110 vl <40 cd% 41

 


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