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Author Topic: switching to new medication  (Read 348 times)

0 Members and 3 Guests are viewing this topic.

Offline sanitex

  • Member
  • Posts: 412
switching to new medication
« on: May 23, 2016, 01:31:32 AM »


H! guys, I'd like know which of these medication is better tolerance (Nivirapine or Edurant)? I'm changing due to anxiety disorder ,panic  etc.
I'm now waitting for the result of Nivirapine to come out according to my doc.and I don't want any medication with food .
27/12/07 cd4 20 vl 1m
10/4 /08 cd4 86 vl 63
1/7/08  cd4 186 vl undetectable
16/10/08 cd4 196 vl undet
23/1/09 cd4 248 vl un
10/9/11 cd4 418 vl <40 %22
13/12/11 cd4 410 vl undet 23%
24/2/12 cd4 545 vl undet 26%
on 22/2/12 change truvada to Recovir-EM
due to no stock on Truvada.
10/9/11 cd4 418 vl <40 %22
7/7/12 cd4 359 vl <40 22%
23/8/12 cd4 400 vl <40 23%,
testosterone test 7.5 ng/ml and
thyroid (TSH)1.32 ml creatinine.eGFR blck 1.5 all fasting test morning.
13/12/2012 cd4 523 24% vl <40
18/3/2013 cd4  513  23% vl <40
reg ATRIPLA
03/8/2013 cd4 429 22% vl <40
13/11/2013 cd4 455 23% vl <40
Anti-HBs test (quantitative ) Anti-HBs positive
Titer 16.95 mlu/ml <10.00
22/3/14 cd4 396 vl <40 24%
24/7/14 tevir
24/9/14 cd4 517 vl <40 22%
16/3/15 cd4 545 vl  85 24%
12/4/16 cd4 626 vl <40 25%

Offline Expat1

  • Member
  • Posts: 18
Re: switching to new medication
« Reply #1 on: May 26, 2016, 10:03:59 AM »
You must take Edurant with a meal.  It needs the stomach acid to activate the medicine.

Nevirapine has no food requirement. There is a lead in dosing for two weeks. Then full dosing after that.  They will be watching you to see if you develop a rash in the first 2weeks.

My boyfriend was on it, and he developed the rash after a few months.  Which is unusual.  Usually it happens sooner.  He had to stop and go back on efavirenz.

Offline sanitex

  • Member
  • Posts: 412
Re: switching to new medication
« Reply #2 on: May 26, 2016, 11:52:54 PM »

  Thanks Expat1,i appreciate your concern but, i hope Nevirapine has nothing to do with CNS ( central nervous system)? I'm really seeing my ass with this Teevir. am afraid of resistance  to be frank.
« Last Edit: May 26, 2016, 11:54:59 PM by sanitex »
27/12/07 cd4 20 vl 1m
10/4 /08 cd4 86 vl 63
1/7/08  cd4 186 vl undetectable
16/10/08 cd4 196 vl undet
23/1/09 cd4 248 vl un
10/9/11 cd4 418 vl <40 %22
13/12/11 cd4 410 vl undet 23%
24/2/12 cd4 545 vl undet 26%
on 22/2/12 change truvada to Recovir-EM
due to no stock on Truvada.
10/9/11 cd4 418 vl <40 %22
7/7/12 cd4 359 vl <40 22%
23/8/12 cd4 400 vl <40 23%,
testosterone test 7.5 ng/ml and
thyroid (TSH)1.32 ml creatinine.eGFR blck 1.5 all fasting test morning.
13/12/2012 cd4 523 24% vl <40
18/3/2013 cd4  513  23% vl <40
reg ATRIPLA
03/8/2013 cd4 429 22% vl <40
13/11/2013 cd4 455 23% vl <40
Anti-HBs test (quantitative ) Anti-HBs positive
Titer 16.95 mlu/ml <10.00
22/3/14 cd4 396 vl <40 24%
24/7/14 tevir
24/9/14 cd4 517 vl <40 22%
16/3/15 cd4 545 vl  85 24%
12/4/16 cd4 626 vl <40 25%

Offline bmancanfly

  • Member
  • Posts: 701
  • Medicare For All !
Re: switching to new medication
« Reply #3 on: May 27, 2016, 06:17:11 PM »
I switched from Atripla to Nevirapine + Truvada many years ago for the same reason - CNS side effects.  The switch helped a lot.

You don't need to do the lead in dose if you are switching directly from Sustiva to Nevirapine without a break in medication.

So long as you don't have a break in medication I wouldn't be too concerned about resistance either.

Best of luck.
"The trouble with the world is that the stupid are cocksure and the intelligent are full of doubt."

 Bertrand Russell

Offline sanitex

  • Member
  • Posts: 412
Re: switching to new medication
« Reply #4 on: May 27, 2016, 11:38:22 PM »



Thanks bmancanfly, I'm waiting for my ID doc to get back to me asap as we wait for test result .
27/12/07 cd4 20 vl 1m
10/4 /08 cd4 86 vl 63
1/7/08  cd4 186 vl undetectable
16/10/08 cd4 196 vl undet
23/1/09 cd4 248 vl un
10/9/11 cd4 418 vl <40 %22
13/12/11 cd4 410 vl undet 23%
24/2/12 cd4 545 vl undet 26%
on 22/2/12 change truvada to Recovir-EM
due to no stock on Truvada.
10/9/11 cd4 418 vl <40 %22
7/7/12 cd4 359 vl <40 22%
23/8/12 cd4 400 vl <40 23%,
testosterone test 7.5 ng/ml and
thyroid (TSH)1.32 ml creatinine.eGFR blck 1.5 all fasting test morning.
13/12/2012 cd4 523 24% vl <40
18/3/2013 cd4  513  23% vl <40
reg ATRIPLA
03/8/2013 cd4 429 22% vl <40
13/11/2013 cd4 455 23% vl <40
Anti-HBs test (quantitative ) Anti-HBs positive
Titer 16.95 mlu/ml <10.00
22/3/14 cd4 396 vl <40 24%
24/7/14 tevir
24/9/14 cd4 517 vl <40 22%
16/3/15 cd4 545 vl  85 24%
12/4/16 cd4 626 vl <40 25%

Offline bmancanfly

  • Member
  • Posts: 701
  • Medicare For All !
Re: switching to new medication
« Reply #5 on: Yesterday at 09:56:45 AM »
Not sure I understand what test you are waiting for.  Could you clarify?
"The trouble with the world is that the stupid are cocksure and the intelligent are full of doubt."

 Bertrand Russell

Offline sanitex

  • Member
  • Posts: 412
Re: switching to new medication
« Reply #6 on: Today at 11:38:12 AM »
   

  H! Bmancanfly, the test is for hypersensitive reaction {HLA *350*1) I can't remember  actually .
Please there's  something  I'd like to know  regarding  kidney  problems,does this nevirapine  has the same  kidney  issues  like tenofovir?
27/12/07 cd4 20 vl 1m
10/4 /08 cd4 86 vl 63
1/7/08  cd4 186 vl undetectable
16/10/08 cd4 196 vl undet
23/1/09 cd4 248 vl un
10/9/11 cd4 418 vl <40 %22
13/12/11 cd4 410 vl undet 23%
24/2/12 cd4 545 vl undet 26%
on 22/2/12 change truvada to Recovir-EM
due to no stock on Truvada.
10/9/11 cd4 418 vl <40 %22
7/7/12 cd4 359 vl <40 22%
23/8/12 cd4 400 vl <40 23%,
testosterone test 7.5 ng/ml and
thyroid (TSH)1.32 ml creatinine.eGFR blck 1.5 all fasting test morning.
13/12/2012 cd4 523 24% vl <40
18/3/2013 cd4  513  23% vl <40
reg ATRIPLA
03/8/2013 cd4 429 22% vl <40
13/11/2013 cd4 455 23% vl <40
Anti-HBs test (quantitative ) Anti-HBs positive
Titer 16.95 mlu/ml <10.00
22/3/14 cd4 396 vl <40 24%
24/7/14 tevir
24/9/14 cd4 517 vl <40 22%
16/3/15 cd4 545 vl  85 24%
12/4/16 cd4 626 vl <40 25%

 


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