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Well Controlled HIV - Risks of Death No Higher Than Rest of Population...

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Common_ground:

--- Quote from: buginme2 on March 13, 2013, 12:55:29 AM ---This study is also flawed because it only takes into account people who have a sustained cd4 count of 500-1000. 

Many people with HIV fail to achieve a cd4 count above 500.  The study noted that those with cd4 counts less than 500 had a significantly higher risk of death.

"Patients with below-normal CD4+ cell counts (350 to 499 cells/mm3) were at elevated risk of death. Based on the standardized mortality ratio, the risk of death in this group was 77 percent higher than in the general population."

Considering much of the world won't even start treatment until you reach a cd4 count of 350 or less, many people don't achieve a response above 500.  Not to mention the scores of people who are diagnosed later.

Not to mention, are they discounting all the people who died of cancer?  Many cancers are related to HIV. 

Just seems that the news is great when you can cherry pick your study population.

http://www.sciencedaily.com/releases/2013/03/130311150951.htm

--- End quote ---

The study do include people with cd4 of 350 - 500 as well. Is 77% alot? In relation to what? Smoking? Obesity? Alcohol? Drugs? Well it depends.

If you would have read the study more carefully it says "The most common causes of death were cardiovascular disease or sudden death, responsible for 31 percent of deaths; and non-HIV-related cancers, 19 percent."
So no, cancers included.

jkinatl2:

--- Quote from: Common_ground on March 13, 2013, 02:35:27 AM ---The study do include people with cd4 of 350 - 500 as well. Is 77% alot? In relation to what? Smoking? Obesity? Alcohol? Drugs? Well it depends.

If you would have read the study more carefully it says "The most common causes of death were cardiovascular disease or sudden death, responsible for 31 percent of deaths; and non-HIV-related cancers, 19 percent."
So no, cancers included.

--- End quote ---

Mayhaps, but didn't a recent study correlate an HIV diagnosis with a 50% rise in cardiovascular-related deaths.

http://www.aidsmap.com/HIV-and-antiretroviral-therapy-increase-risk-of-cardiovascular-disease-shows-meta-analysis/page/2493594/

Even - especially - with certain ART. Honestly I am not being a Debbie Downer here. Just trying to find perspective in what often amounts to a shrill keen of unbridled optimistic lust which is inevitably tempered with the multitude of caveats from those whose anecdotes differ.

Common_ground:

--- Quote from: jkinatl2 on March 13, 2013, 01:24:57 AM ---
There is compelling evidence that longevity and quality of health are more accurately measured by the nadir cd3 count. In other words, at our current (albeit fluid) quality of care, if you had a cd4 count of 100, but now have a cd4 count of 800, your lowest measured cd4 count is the standard used to determine your personal health prognosis. Well, that and the zillion other things that each individual possesses which makes up their biology.


--- End quote ---

The study contradicts that.

"...in HIV-infected patients with a CD4+ cell count of 500 cells/mm3 or higher, the risk of death was not significantly higher than in the general population. For this group, the risk of death was essentially normal regardless of how low the CD4+ cell count dipped during treatment, as long as it returned to normal."


Miss Philicia:
Frankly I don't really care about any of this because we're all going to be cured by bee stings next month.

Common_ground:

--- Quote from: jkinatl2 on March 13, 2013, 02:43:42 AM ---Mayhaps, but didn't a recent study correlate an HIV diagnosis with a 50% rise in cardiovascular-related deaths.

http://www.aidsmap.com/HIV-and-antiretroviral-therapy-increase-risk-of-cardiovascular-disease-shows-meta-analysis/page/2493594/

Even - especially - with certain ART. Honestly I am not being a Debbie Downer here. Just trying to find perspective in what often amounts to a shrill keen of unbridled optimistic lust which is inevitably tempered with the multitude of caveats from those whose anecdotes differ.

--- End quote ---

I often stress that we need to see people live a normal lifespan to actually be able to claim that "normal life expectancy" can be achieved with HIV. So sure, we are not really over the bridge yet and its healthy , no pun inteded, to question, although I remain slightly optimistic and science seems to support that view in 2013.

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