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Author Topic: HIV Reprogrammed to fight cancer  (Read 1923 times)

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Offline phildinftlaudy

  • Member
  • Posts: 2,965
  • sweet Ann what you think babe...
HIV Reprogrammed to fight cancer
« on: December 10, 2012, 06:46:46 PM »
http://www.medicaldaily.com/articles/13465/20121210/revolutionary-treatment-uses-hiv-reprogram-cells-fighting.htm

Revolutionary Treatment Uses HIV to Reprogram Cells Into Fighting Cancer
 
The treatment uses a disabled version of the virus that causes AIDS to reprogram the genes of a personís immune system and retrain it to kill cancer cells.


The treatment uses a disabled version of the virus that causes AIDS to reprogram the genes of a person's immune system and retrain it to kill cancer cells. Researchers remove millions of the patients' T-cells, a type of white blood cell, and insert new genes that would allow the T-cells to kill cancerous ones. Disabled HIV is used for the treatment because the virus is good at transmitting genetic material into T-cells. Then the engineered T-cells are pumped back into the body where they are intended to attack B-cells, which turn malignant during leukemia. The reengineered cells can stay in the body for years, though not at the same level as when fighting the disease.
September 13, 2008 - diagnosed +
Labs:
Date    CD4    %   VL     Date  CD4  %   VL
10/08  636    35  510   9/09 473  38 2900  12/4/09 Atripla
12/09  540    30    60   
12/10  740    41  <48   
8/11    667    36  <20  
03/12  1,041  42  <20
05/12  1,241  47  <20
08/12   780    37  <20
11/12   549    35  <20
02/12  1,102  42  <20
11/12   549    35  <20

Online tednlou2

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  • Posts: 4,988
Re: HIV Reprogrammed to fight cancer
« Reply #1 on: December 10, 2012, 11:17:17 PM »
ABC News featured a story tonight about this.  It was used on a young girl with cancer.  The video is at the bottom of the story.  This will probably cause more interest in HIV research by those who wouldn't otherwise be. 

http://abcnews.go.com/blogs/health/2012/12/10/doctors-find-success-using-retooled-hiv-to-fight-leukemia/

Offline wolfter

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  • Posts: 4,650
Re: HIV Reprogrammed to fight cancer
« Reply #2 on: December 10, 2012, 11:27:47 PM »
Exciting advancements seem to be coming regularly these days.  I hope it does spur further research.

thanks for sharing
Complacency is the enemy.  ;)  Challenge yourself daily for maximum  return on investment.

Offline Jmarksto

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  • Posts: 513
Re: HIV Reprogrammed to fight cancer
« Reply #3 on: December 11, 2012, 02:02:04 AM »
I saw this article too -- I couldn't help but think about the contrast.  What a blessing that HIV had (at least in a minor way) for one young girl and her family - against all of the suffering this disease has caused.

Lets hope this very small light grows against the darkness of HIV's past.
03/15/12 Negative
06/15/12 Positive
07/11/12 CD4 790          VL 4,000
08/06/12 CD4 816/38%   VL 49,300
08/20/12 Started Complera
11/06/12 CD4   819/41% VL 38
02/11/13 CD4   935/41% VL UD
06/06/13 CD4   816/41% VL UD
10/28/13 CD4 1131/45%  VL 25
02/25/14 CD4   792/37%  VL UD
07/09/14 CD4 1004/39%   VL UD

Offline skycee

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  • Posts: 72
  • oh you are having a bad day? Did you die?
Re: HIV Reprogrammed to fight cancer
« Reply #4 on: December 11, 2012, 10:28:54 AM »
Jmark you took it off my lips....truly an irony of life and a blessing to this young lady.....i bet if you did ask her she wld affirm that hiv is a good thing....

On the other hand, I was wondering if same process can't be applied in developing a cure, ie re-engineering the virus, to be able to kill the virus itself....

Just thinking......
Infected September's 2012
Seroconverted October 2012
Elisa test- indeterminate 20th November. 2012
Rapid test - Negative 23th November 2012
Elisa test - Positive 10th December 2012
CD4 - 546, 12th Dec 2012
CD4 600+, VL 6702 26th March 2013

Offline YellowFever

  • Member
  • Posts: 163
Re: HIV Reprogrammed to fight cancer
« Reply #5 on: December 26, 2012, 11:16:22 PM »
I'm sure this will set the denialists' tongues wagging "See! It doesn't cause AIDS!"
08/2010 HIV- 08/2012 HIV+
10/2012 CD4 415(15%)
04/2013 CD4 457(15%)
10/2013 CD4 520 (20%) VL 650 (wtf?)
02/2014 CD4 410(20%) VL 390 (yay!)
08/2014 CD4 580(?%)

 


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