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Author Topic: Is Atripla affecting my mood?  (Read 2384 times)

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Offline TabooPrincess

  • Member
  • Posts: 279
Is Atripla affecting my mood?
« on: November 26, 2012, 12:14:40 PM »
Been on atripla around 5 months and all good going - no real side-effects other than the messed up sleep.  But I just feel wrong in myself, like I'm on the wrong path/track in life and a general feeling of miserableness and underlying panic/anxiety which I'm in control of at the moment.  I'm not depressed, nowhere near but I just feel wrong.

Is this likely to be atripla or just life in general?  I've always been a fairly content happy-go-lucky person but I seem to be so highly strung lately and can't see anything good in the future, just the same old weariness.  Nothing has changed in my life only taking atripla so I don't know....

I'm not sure if I should request a change or not since everything else about atripla suits me fine.  Any ideas?!
09/ 2008 - Seroconversion
11/2008 - Tested pos, cd4 640 vl 25400
12/2008 - cd4 794 vl 27798, 35%
03/2009 - cd4 844 vl 68846, 35%
06/2009 - cd4 476 vl 49151, 33% (pregnancy confirmed)
08/2009 - cd4 464 vl 54662, 32%
Started meds for pregnancy (Kaletra, AZT, Viread)
09/2009 - cd4 841 vl 3213, 42%
10/2009 - cd4 860 vl 1088, 41%
11/2009 - cd4 771 vl 563, 38%
12/2009 - cd4 885 vl 151 42%
Discontinued meds after baby born
02/2010 - cd4 841 vl 63781, 38%
05/2010 - cd4 1080 vl 113000, 39%
08/2010 - cd4 770 vl 109242
12/2010 - cd4 642 vl 111000, 34%
06/2011 - cd4 450 vl 222000, 33%
11/2011 - cd4 419 vl 212000, 24%
03/2012 - cd4 280 vl 118000, 26% (repeated Cd4 at 360)
05/2012 -cd4 360 vl 99,190
10/2012 Atripla, cd4 690, vl 80
12/2012 Darunavir, norvir, truvada, Cd4 680, vl u/d
07/2013 cd4 750,ud

Offline jkinatl2

  • Member
  • Posts: 6,007
  • Doo. Dah. Dipp-ity.
Re: Is Atripla affecting my mood?
« Reply #1 on: November 26, 2012, 12:23:05 PM »
That sounds almost exactly like me on Sustiva. Took months for the CNS effects to fully kick in. I ended up suicidal, which is entirely not me. I would take these changes in mood  seriously.
"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

Welcome Thread

Offline TabooPrincess

  • Member
  • Posts: 279
Re: Is Atripla affecting my mood?
« Reply #2 on: November 26, 2012, 12:29:59 PM »
I didn't know if it might because it's winter, or I've put on weight, or I'm just pissed off with my job (which incidentally has been suffering lately), or I might want to move house, or move city, or change partners, or it's just natural with age, or I want another baby/don't want a another baby, or I'm exhausted....the list is endless and I'm tired of it all lol  just want to be content with my lot again.

And yeh - it is getting worse as the weeks go by. 
09/ 2008 - Seroconversion
11/2008 - Tested pos, cd4 640 vl 25400
12/2008 - cd4 794 vl 27798, 35%
03/2009 - cd4 844 vl 68846, 35%
06/2009 - cd4 476 vl 49151, 33% (pregnancy confirmed)
08/2009 - cd4 464 vl 54662, 32%
Started meds for pregnancy (Kaletra, AZT, Viread)
09/2009 - cd4 841 vl 3213, 42%
10/2009 - cd4 860 vl 1088, 41%
11/2009 - cd4 771 vl 563, 38%
12/2009 - cd4 885 vl 151 42%
Discontinued meds after baby born
02/2010 - cd4 841 vl 63781, 38%
05/2010 - cd4 1080 vl 113000, 39%
08/2010 - cd4 770 vl 109242
12/2010 - cd4 642 vl 111000, 34%
06/2011 - cd4 450 vl 222000, 33%
11/2011 - cd4 419 vl 212000, 24%
03/2012 - cd4 280 vl 118000, 26% (repeated Cd4 at 360)
05/2012 -cd4 360 vl 99,190
10/2012 Atripla, cd4 690, vl 80
12/2012 Darunavir, norvir, truvada, Cd4 680, vl u/d
07/2013 cd4 750,ud

Offline PozBrian

  • Member
  • Posts: 200
Re: Is Atripla affecting my mood?
« Reply #3 on: November 26, 2012, 05:00:18 PM »
I was in the same place after about 2 years on Atripla. I was also very quick to get angry which is not normal for me. My DR and I discussed several times switching off Atripla but I didn't think (wrongly) that it was affecting me. After all how could I be depressed if I could still laugh at jokes! I didn't really want to give up the one-a-day pill.

About a year ago, I switched to Issentress and Truvada. A week after the switch I caught myself walking down the street with a spring in my step and whistling! Feeling much better, laugh easier, and some stool issues I was having cleared up. Though that took a little longer. I didn't realize the cloud I was under until it was gone. Now I wish I had made the switch sooner.

Three pills a day vice one is a little more challenging to manage sometimes, specially with my work schedule, but it isn't that big a deal.
3/8 CD4: 495, 31%, VL UD
2/1 CD4: 564, 20%.VL UD, switching to Issentress & truvada
10/11 CD4: 446, 29%, VL UD
7/11 CD4: 873, 35%, VL UD
4/11 CD4: 573, 34% VL 0
12/10 CD4: 405, 30% VL UD
9/10 CD4: 416, 31% VL UD
5/10 CD4: 393, 29% VL: UD
02/10 CD4: 423, 37% VL: UD
11/09 CD4: 379, 25% VL: UNDETECTABLE!!
10/09 CD4: 245, 25% VL: 87
9/09 CD4: 246, 24% VL: 49!
8/09 CD4: 277, 26% VL: 115
7/09 CD4: 346, 24% VL: 221
6/09 started Atripla
5/09 CD4: 326, 16%  VL:125000
4/09 HIV +, CD4: 397, 16%  VL:195000, PPD reactive

Offline mecch

  • Member
  • Posts: 12,037
  • red pill? or blue pill?
Re: Is Atripla affecting my mood?
« Reply #4 on: November 26, 2012, 05:41:32 PM »
By all means change your combo.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline Hellraiser

  • Member
  • Posts: 4,140
  • Semi-misanthropic
Re: Is Atripla affecting my mood?
« Reply #5 on: November 26, 2012, 05:55:43 PM »
I was on Atripla for 2.5 years.  At the end of year 1 I could tell my behavior had changed.  I was more anxious and became extremely defensive aqt the drop of a hat.  I took it as long as I could and then I swapped to Complera.  All of that shit faded away.  Talk to your doctor about different combos.  Isentress + Truvada, Stribild, Complera, should all be brought up.

Offline Plus30

  • Member
  • Posts: 26
Re: Is Atripla affecting my mood?
« Reply #6 on: November 26, 2012, 08:16:14 PM »
I was on Atripla and tell everyone how bad it was for me. This does not mean it won't work for other people. Some love it. I was on it for four years. I had the dreams, but they never stopped. I had vivid dreams every single night for four years. I was very weak, and I felt like a zombie. I was just not right. It was more gradual, but all I could do was be tired. When I switched I felt like I could THINK again, I felt more like myself. It was a big difference.
...............CD4   %    VL
05/04/07   Tested Positive
10/24/07   343   18   141,000
03/12/08   327   17   120,000
05/08/08   286   13   16,529  Started Atripla
07/16/08   325   14   282 
10/14/08   317   19   72
06/10/09   392   21   <48
04/15/10   385   23   <48 New Dr
09/10/10   430   33   <48
11/29/10   540   28   <20
04/11/11   580   29   <20
06/24/11   465   31   70
01/06/12   427   26   <20
04/12/12   378   23   <20 Change to Truvada/Viramune
05/15/12   461   30   <20
10/02/12   678   28   <20
02/22/13   720   27   <20

Offline Fisher

  • Member
  • Posts: 283
Re: Is Atripla affecting my mood?
« Reply #7 on: November 27, 2012, 04:45:05 PM »
Taboo:

Is there anything you do for mess up sleep? On Atripla for about a month, and have the toughest time falling alseep.  Not sure about depression, but I'm not laughing a helluva lot these days.  Maybe, to understand if one is in depression one's got to be out of it to realize being in it. Do know that the things that used to make me tick and click don't do much for me know, and I need to find some inspiration figuring out something else . . . God knows what.

-fisher




- fisher
09/22 CD 385 %22 VL UD
07/14 CD 391 %20 VL UD
04/14 CD 486 %23 VL <20
11/13 CD 351 %21  VL <20
10/13 CD 390 %16  VL <20
06/13 CD 315 %19  VL  22
02/13 CD 396 %14  VL <20
12/12 CD 392 %13  VL 320
11/12 CD 428 %13  VL 1200
*Started Meds: Atripla
10/12 CD 427 %11  VL 139000 -- 09/12 CD 408 %13 VL 92928
09/11 CD 745 %27 VL CLOT -- 10/10 CD 863 %29 VL 2782
10/09 CD 597 %30 VL 2537 -- 05/08 CD 809 %28 VL 1504
04/07 CD 797 %25 VL 3558 -- 11/06 CD 720 %28 VL 1214
06/05 CD 731 %25 VL 1575 -- 12/04 CD 1176 %30 VL 1329
01/04 CD 959 %26 VL 1011 -- 11/03 CD 1000 %28 VL 1581
12/02 CD 748 %28 -- 10/01 CD 860 %25
08/00 CD 1022 %28 -- 04/99 CD 854 %27
11/98 CD 899 %28 -- 02/97 CD 1400 %37
11/96 CD 1325  VL <500 -- 09/96 – Western Blot
05/83 – 04/98 - Monogamous Partner Being Negative
ARS - LA '82

Offline Hellraiser

  • Member
  • Posts: 4,140
  • Semi-misanthropic
Re: Is Atripla affecting my mood?
« Reply #8 on: November 28, 2012, 10:17:27 AM »
Taboo:

Is there anything you do for mess up sleep? On Atripla for about a month, and have the toughest time falling alseep.  Not sure about depression, but I'm not laughing a helluva lot these days.  Maybe, to understand if one is in depression one's got to be out of it to realize being in it. Do know that the things that used to make me tick and click don't do much for me know, and I need to find some inspiration figuring out something else . . . God knows what.

-fisher

I had a big problem sleeping on Atripla and when I did sleep it wasn't very restful.  This was probably the largest contribution to me changing regimens.

Offline TabooPrincess

  • Member
  • Posts: 279
Re: Is Atripla affecting my mood?
« Reply #9 on: December 10, 2012, 02:46:39 PM »
I'm getting my new meds tomorrow - I've opted for truvada and darunavir.  My mood has been getting worse, I feel so dark and bleak.  I can't see any light at the end of the tunnel, just panic and fear.  I never feel like I'm fully awake and sometimes struggle to remember what really happened and what didn't when the dreams are too vivid.  I hope the change will ease this, otherwise it's back to the drawing board and accepting that I'm just a miserable cow these days.
09/ 2008 - Seroconversion
11/2008 - Tested pos, cd4 640 vl 25400
12/2008 - cd4 794 vl 27798, 35%
03/2009 - cd4 844 vl 68846, 35%
06/2009 - cd4 476 vl 49151, 33% (pregnancy confirmed)
08/2009 - cd4 464 vl 54662, 32%
Started meds for pregnancy (Kaletra, AZT, Viread)
09/2009 - cd4 841 vl 3213, 42%
10/2009 - cd4 860 vl 1088, 41%
11/2009 - cd4 771 vl 563, 38%
12/2009 - cd4 885 vl 151 42%
Discontinued meds after baby born
02/2010 - cd4 841 vl 63781, 38%
05/2010 - cd4 1080 vl 113000, 39%
08/2010 - cd4 770 vl 109242
12/2010 - cd4 642 vl 111000, 34%
06/2011 - cd4 450 vl 222000, 33%
11/2011 - cd4 419 vl 212000, 24%
03/2012 - cd4 280 vl 118000, 26% (repeated Cd4 at 360)
05/2012 -cd4 360 vl 99,190
10/2012 Atripla, cd4 690, vl 80
12/2012 Darunavir, norvir, truvada, Cd4 680, vl u/d
07/2013 cd4 750,ud

Offline TabooPrincess

  • Member
  • Posts: 279
Re: Is Atripla affecting my mood?
« Reply #10 on: December 10, 2012, 02:52:01 PM »
Oh and my consultant has not said anything about norvir.  Is this always needed?
09/ 2008 - Seroconversion
11/2008 - Tested pos, cd4 640 vl 25400
12/2008 - cd4 794 vl 27798, 35%
03/2009 - cd4 844 vl 68846, 35%
06/2009 - cd4 476 vl 49151, 33% (pregnancy confirmed)
08/2009 - cd4 464 vl 54662, 32%
Started meds for pregnancy (Kaletra, AZT, Viread)
09/2009 - cd4 841 vl 3213, 42%
10/2009 - cd4 860 vl 1088, 41%
11/2009 - cd4 771 vl 563, 38%
12/2009 - cd4 885 vl 151 42%
Discontinued meds after baby born
02/2010 - cd4 841 vl 63781, 38%
05/2010 - cd4 1080 vl 113000, 39%
08/2010 - cd4 770 vl 109242
12/2010 - cd4 642 vl 111000, 34%
06/2011 - cd4 450 vl 222000, 33%
11/2011 - cd4 419 vl 212000, 24%
03/2012 - cd4 280 vl 118000, 26% (repeated Cd4 at 360)
05/2012 -cd4 360 vl 99,190
10/2012 Atripla, cd4 690, vl 80
12/2012 Darunavir, norvir, truvada, Cd4 680, vl u/d
07/2013 cd4 750,ud

Offline Ann

  • Administrator
  • Member
  • Posts: 28,140
  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: Is Atripla affecting my mood?
« Reply #11 on: December 10, 2012, 04:28:44 PM »
I've been on Truvada, Prezista (darunavir) and Norvir since last July and I like it.

I was advised (both by people here and by my consultant) that if I'm going to take it (Prezista) with Truvada, I have to take Norvir as well. You should double-check with your consultant about this. I remember specifically discussing this with my doc (because I'd hoped to avoid Norvir) and he said he absolutely did not recommend going without Norvir.

Aside from a little more diarrhea than usual in the first week or so, Norvir hasn't been a problem for me. It just takes a little getting used to for your gut. (Caveat - for a small minority, it continues to be a problem.) I worried about Norvir because I've already been dealing with hiv related diarrhea for over ten years and I was wary of making it worse and no longer being able to control it as I do now. But like I said, aside from the first week or so it hasn't been a problem.
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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline Miss Philicia

  • Member
  • Posts: 24,418
  • celebrity poster, faker & poser
Re: Is Atripla affecting my mood?
« Reply #12 on: December 10, 2012, 04:35:22 PM »
I've been on Prezista since it was in clinical trials. Like Ann, I've not heard of taking it without Norvir.
"I’ve slept with enough men to know that I’m not gay"

Offline RobbyR

  • Member
  • Posts: 341
Re: Is Atripla affecting my mood?
« Reply #13 on: December 10, 2012, 08:08:30 PM »
Everyone's experience is different. For me, Atripla was the first HIV drug I took, and it worked wonders for me. It kept me undetectable the whole time I was on it. And overall (other than first week feeling extremely loopy and stoned). I never had really weird dreams on it. After about a year on it I started having slight bouts of anxiety. I also had bouts of strange thoughts and sometimes downright sadness. I also had some dizziness, and having a LOT of trouble falling asleep at night, when I had never had that problem before. The sleep problem was the straw that broke the camel's back for me. So all in all I liked Atripla and it did a lot of good things for me, but in the end I decided to take my doc's advice and try a similar medication, Complera, which does not have the sustiva in it. I just needed my sleep, but wanted to stick to a very similar medicine, so Complera was what I decided on. You have to do your research and decide what med combo you think will best suit your needs. Good luck.
Started Atripla August, 2010.

 


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