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Author Topic: when do you think there will be a cure for HIV?  (Read 7743 times)

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Offline Hellraiser

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Re: when do you think there will be a cure for HIV?
« Reply #50 on: November 22, 2012, 11:23:48 PM »
I will have you know I am at a CD4 count of 240ish.  Which I think now exempts me from needing regular prophylactic antibiotics.  Also, I thought the VL count was not "proof" in and of itself?  On that note I've been undetectable sinced about 6 months from starting meds.

Offline leatherman

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Re: when do you think there will be a cure for HIV?
« Reply #51 on: November 23, 2012, 12:43:14 AM »
I thought the VL count was not "proof" in and of itself?
I'm glad to hear about your improved numbers ;D

a doctor giving you a diagnosis of being HIV+ and having a viral load is a pretty good way to know one has HIV. ;) Just for the record, I never saw a piece of paper (or it never registered in my brain in 1992-93 if I was shown it), that stated I was HIV poz. I would imagine that a lot of doctors give out a lot of diagnoses about a lot of illnesses without ever showing the patient a piece of paper. Is there an underlying reason why you wouldn't believe the diagnosis your doctor gave you? If it concerns you, have you asked to see the result paper from the lab?

I'm not looking to put you on the spot or even get an answer from you. I was just throwing that out there since you expressed concern about your status even though a doctor gave you a diagnosis. ;) I think if I were you, I'd take the easy solution to this and ask to clarify that all up at my next doctor appt, just to have it all straight in my head. ;)
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline Fisher

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Re: when do you think there will be a cure for HIV?
« Reply #52 on: November 23, 2012, 01:00:28 AM »
Perhaps a humor thread, or thread just for taunting should be started. And, if you did not see Rigley's "Believe it or not," you missed the cure. Tsk, Tsk.

-fisher

- fisher
04/14 CD 486 %23 VL <20
11/13 CD 351 %21  VL <20
10/13 CD 390 %16  VL <20
06/13 CD 315 %19  VL  22
02/13 CD 396 %14  VL <20
12/12 CD 392 %13  VL 320
11/12 CD 428 %13  VL 1200
*Started Meds: Atripla
10/12 CD 427 %11  VL 139000 -- 09/12 CD 408 %13 VL 92928
09/11 CD 745 %27 VL CLOT -- 10/10 CD 863 %29 VL 2782
10/09 CD 597 %30 VL 2537 -- 05/08 CD 809 %28 VL 1504
04/07 CD 797 %25 VL 3558 -- 11/06 CD 720 %28 VL 1214
06/05 CD 731 %25 VL 1575 -- 12/04 CD 1176 %30 VL 1329
01/04 CD 959 %26 VL 1011 -- 11/03 CD 1000 %28 VL 1581
12/02 CD 748 %28 -- 10/01 CD 860 %25
08/00 CD 1022 %28 -- 04/99 CD 854 %27
11/98 CD 899 %28 -- 02/97 CD 1400 %37
11/96 CD 1325  VL <500 -- 09/96 – Western Blot
05/83 – 04/98 - Monogamous Partner Being Negative
ARS - Los Angeles Dec '82

Offline mecch

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  • red pill? or blue pill?
Re: when do you think there will be a cure for HIV?
« Reply #53 on: November 23, 2012, 03:55:05 AM »
Hellraiser is this a real thought, or just bemused speculation?

If you care to know, I am sure you can ask the nurse or doctor to show you a few pages of your lab results over the years and show you whats on them.  Your doctors will know your genotype.  Of the hiv virus that IS IN YOU and which is successfully repressed by your hiv medicine.   

Once you get the name of the genotype, you could google it and find a good image, print it out and paste it somewhere in your apt and voila there's your piece of paper.

HIV is probably stamped all over all your medical records right now. Just have a peak. 

How did we get onto this tangent again?
« Last Edit: November 23, 2012, 03:58:06 AM by mecch »
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline mecch

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  • red pill? or blue pill?
Re: when do you think there will be a cure for HIV?
« Reply #54 on: November 23, 2012, 04:03:43 AM »
Just this week here in Switzerland I was talking to a guy about 30 years old. He is HIV+ and was on treatment for a few years and now has gone off treatment because "there are many unanswered questions about the virus and the treatment" and, yeah, here it comes, told me all about how now he follows alternative treatment with a "naturopath" and about how his doctor was on board and yada yada yada and I thought, geez louise, 2012, and this shit is still happening.... 
Oh, yes, and Obama stole the election... And other myths we tell ourselves I dunno why, since we know its malarky.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline Since2005

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Re: when do you think there will be a cure for HIV?
« Reply #55 on: November 23, 2012, 05:21:19 PM »
I like to search google.com/news on the latest HIV news and there are articles that we are close to the cure (but still years away) ...

what is your opinion?
What form of cure do you think it will be? stem cell? vaccinne? pills?

10 sounds very ambitious? Hmm
May be 15/20 years..

Thanks to the member who shared about the article on 'boosting immune'
So hope continues...

Offline thunter34

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  • His name is Carl.
Re: when do you think there will be a cure for HIV?
« Reply #56 on: November 23, 2012, 06:39:32 PM »
Hellraiser is this a real thought, or just bemused speculation?

HIV is probably stamped all over all your medical records right now. Just have a peak. 



I had to raise an eyebrow at this, too...but then maybe I'm just over-obsessive about details.  Have you not ever seen - or asked for personal duplicates of - copies of any of your medical stuff?  I'm just wondering because I've asked several times for print outs of papers related to my VL and counts, etc.


And on a side note about perhaps being over-obsessive:  it's "peek", Mr. Educator.   ;)
AIDS isn't for sissies.

Offline elf

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Re: when do you think there will be a cure for HIV?
« Reply #57 on: November 24, 2012, 04:58:55 AM »
There will be no cure because status quo (''chronic disease'') is more profitable for big pharma companies...
Let's have a Kiki!

Offline mecch

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  • red pill? or blue pill?
Re: when do you think there will be a cure for HIV?
« Reply #58 on: November 24, 2012, 05:18:13 AM »
There will be no cure because status quo (''chronic disease'') is more profitable for big pharma companies...

Then why is Gilead about to market a non interferon treatment that cures Hep C?  For which they expect to make billions.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline Common_ground

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Re: when do you think there will be a cure for HIV?
« Reply #59 on: November 24, 2012, 07:44:13 AM »
There will be no cure because status quo (''chronic disease'') is more profitable for big pharma companies...

So I guess you also believe
a) There is no competition (free market powers) in the pharma/medical business.
b) The holder of a cure would not make an enormous  profit for years ahead ( possibly indefinitely) in patent rights.
2011 May - Neg.
2012 June CD4:205, 16% VL:2676 Start Truvada/Stocrin
2012 July  CD4:234, 18% VL:88
2012 Sep  CD4:238, 17% VL:UD
2013 Feb  CD4:257, 24% VL:UD -viramune/truvada
2013 May CD4:276, 26% VL:UD

Offline dale gribble

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  • Posts: 12
Re: when do you think there will be a cure for HIV?
« Reply #60 on: November 24, 2012, 02:43:58 PM »
so far as of right now nothing was confirmed
from my specialist nothing as of now like to see a cure but nothing is in sight
people hiv isn't a joke I just read a comment from someone that  stopped taking his meds i'm on my 4th month I don't want to go through it

Offline mecch

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  • red pill? or blue pill?
Re: when do you think there will be a cure for HIV?
« Reply #61 on: November 24, 2012, 03:23:21 PM »
scratch that post.
I've got my answer.
« Last Edit: November 24, 2012, 03:30:12 PM by mecch »
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline Hellraiser

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  • Semi-misanthropic
Re: when do you think there will be a cure for HIV?
« Reply #62 on: November 24, 2012, 05:19:06 PM »
All I was saying was that from what I Recall they always said they "thought" I was positive, but were always awaiting a confirmatory test.  But yes we have genotypes and all that.  Bemused speculation :P

Offline dale gribble

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Re: when do you think there will be a cure for HIV?
« Reply #63 on: November 24, 2012, 06:48:34 PM »
there's no cure as of now

Offline Rev. Moon

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Re: when do you think there will be a cure for HIV?
« Reply #64 on: November 24, 2012, 06:59:07 PM »
All I was saying was that from what I Recall they always said they "thought" I was positive, but were always awaiting a confirmatory test.  But yes we have genotypes and all that.  Bemused speculation :P

I will have you know I am at a CD4 count of 240ish.  Which I think now exempts me from needing regular prophylactic antibiotics.  Also, I thought the VL count was not "proof" in and of itself?  On that note I've been undetectable sinced about 6 months from starting meds.

Gerrrrl, you thinking too much.  Should I conclude that you stopped taking the antibiotics without ever consulting this with your physician or ID specialist?  No, no, no, no.

And as the Swiss professor noted, you never get/request a copy of your labs?  I'd expect better from someone who, IIRC, did his undergraduate studies in a scientific discipline.
"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

Offline Fisher

  • Member
  • Posts: 272
Re: when do you think there will be a cure for HIV?
« Reply #65 on: November 25, 2012, 12:29:44 PM »
Those cupcakes are disgusting. EEEEeeeeeee. Please send me a baker's dozen.
- fisher
04/14 CD 486 %23 VL <20
11/13 CD 351 %21  VL <20
10/13 CD 390 %16  VL <20
06/13 CD 315 %19  VL  22
02/13 CD 396 %14  VL <20
12/12 CD 392 %13  VL 320
11/12 CD 428 %13  VL 1200
*Started Meds: Atripla
10/12 CD 427 %11  VL 139000 -- 09/12 CD 408 %13 VL 92928
09/11 CD 745 %27 VL CLOT -- 10/10 CD 863 %29 VL 2782
10/09 CD 597 %30 VL 2537 -- 05/08 CD 809 %28 VL 1504
04/07 CD 797 %25 VL 3558 -- 11/06 CD 720 %28 VL 1214
06/05 CD 731 %25 VL 1575 -- 12/04 CD 1176 %30 VL 1329
01/04 CD 959 %26 VL 1011 -- 11/03 CD 1000 %28 VL 1581
12/02 CD 748 %28 -- 10/01 CD 860 %25
08/00 CD 1022 %28 -- 04/99 CD 854 %27
11/98 CD 899 %28 -- 02/97 CD 1400 %37
11/96 CD 1325  VL <500 -- 09/96 – Western Blot
05/83 – 04/98 - Monogamous Partner Being Negative
ARS - Los Angeles Dec '82

Offline Mrmojorisin

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  • Posts: 207
    • My Blog
Re: when do you think there will be a cure for HIV?
« Reply #66 on: November 25, 2012, 01:33:51 PM »
I just saw a video that explained the sour cream is the cause of AIDS and whipped cream is the cure :o
Started Meds On 5/1/2012 Norvair, Truvada, Prezista, and Bactrim

4/17/2012--CD4 83/ VL 353,000  7.0%
5/15/2012--CD4 218/ VL 4,970    14.1%
6/27/2012--CD4 146/ VL 420      6.1%
10/11/2012-CD4-223/ VL-62       9.5%
2/14/2013--CD4-215/ VL-119      13.6%
7/3/2013---CD4-256/ VL-UD       18.0%
10/18/2013 CD4-223/ VL-UD       22.2%
01/23/2014-CD4-381/VL-UD       25.3%--Dropped the Bactrim

"arrrrhhhhh ahhrrhhhhh aaaarrhhh"- Chewbacca

Offline Mrmojorisin

  • Member
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    • My Blog
Re: when do you think there will be a cure for HIV?
« Reply #67 on: November 25, 2012, 01:37:40 PM »
Just this week here in Switzerland I was talking to a guy about 30 years old. He is HIV+ and was on treatment for a few years and now has gone off treatment because "there are many unanswered questions about the virus and the treatment" and, yeah, here it comes, told me all about how now he follows alternative treatment with a "naturopath" and about how his doctor was on board and yada yada yada and I thought, geez louise, 2012, and this shit is still happening.... 
Oh, yes, and Obama stole the election... And other myths we tell ourselves I dunno why, since we know its malarky.
Obama didn't steal the election..He paid for it fair and square. He showed me the reciept.
Started Meds On 5/1/2012 Norvair, Truvada, Prezista, and Bactrim

4/17/2012--CD4 83/ VL 353,000  7.0%
5/15/2012--CD4 218/ VL 4,970    14.1%
6/27/2012--CD4 146/ VL 420      6.1%
10/11/2012-CD4-223/ VL-62       9.5%
2/14/2013--CD4-215/ VL-119      13.6%
7/3/2013---CD4-256/ VL-UD       18.0%
10/18/2013 CD4-223/ VL-UD       22.2%
01/23/2014-CD4-381/VL-UD       25.3%--Dropped the Bactrim

"arrrrhhhhh ahhrrhhhhh aaaarrhhh"- Chewbacca

Offline elf

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  • Posts: 596
Let's have a Kiki!

Offline Rev. Moon

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  • Smart ass faggot ©
Re: when do you think there will be a cure for HIV?
« Reply #69 on: November 30, 2012, 10:44:55 PM »
Well, it does look very grim  :-\

http://www.thebodypro.com/content/69595/toward-an-hiv-cure-overview-and-latest-strategies.html?getPage=2


That was actually a pretty decent article.  Thanks for sharing.

I have to say though, I'm not sure what's so grim about it.  We just need to stop these expectations about turning the tv on tomorrow and finding a flashing headline announcing that the cure for teh AIDS has been found.  We've been hearing about "ten years" since 1985 or so.  We have to be realistic. 

One thing that I wanted to highlight from that article was the link towards the end discussing the Visconti Cohort, which should be of great interest to anyone who started treatment shortly after/during the initial stages of infection (i.e. yours truly).  Some of the people in this study have been able to control the virus without meds for seven years (after being on them for three) in a way that's sort of similar to an elite controller. 

It also provides some good insight/evidence when it comes to the discussion about how soon people should start meds.

http://www.thebodypro.com/content/69044/on-the-hiv-cure-front.html

Quote
On the HIV Cure Front
From Test Positive Aware Network
September/October 2012

A group of patients in France who became infected with HIV and then started on antiretroviral therapy (ART) early in the post-infection period have shown no signs of a resurgence of their HIV infection seven years after being taken off therapy.
"These results suggest that ... antiretroviral treatment should be started very early after infection," said Charline Bacchus, lead researcher of the study at the French National Agency for Research on AIDS and Viral Hepatitis (ANRS).
The patients in the ANRS EP47 VISCONTI cohort (known as the Visconti Cohort) have an extremely low reservoir of HIV in their cells similar to that of "HIV controller" patients. HIV controllers are those who are able to control their HIV infection without the use of ART for an extended period of time, and represent about one out of every 300 people who have HIV.

In the study, 12 patients started therapy within 10 weeks of infection, were on therapy for an average of three years, and were able to control HIV after an average of seven years off therapy. At a press conference Asier Saez-Cirión, one of the study investigators, said they were interested in finding out whether HIV controller status could be induced. He estimated that 5-15% of those treated early could eventually control HIV off therapy. But don't stop those HIV meds just yet -- not only would we need to figure out how to identify who would have this type of response to early treatment, but also get those individuals onto treatment immediately following infection. The other question one might ask is, could some of those in the study already have been HIV controllers to begin with? While the genetic alleles commonly associated with HIV controllers was not found in these patients there may be other factors playing a role, which researchers now are trying to uncover.

Another study looked at two men who had been infected with HIV for many years, on suppressive antiretroviral therapy (ART), and who underwent treatment of lymphoma via an allogenic (meaning foreign, or from another donor) stem cell transplantation. Both patients received a milder form of chemotherapy, known as the conditioning regimen, prior to transplant, which allowed them to stay on their ART during and after the transplant. One patient was on Atripla, the other on Isentress/Truvada. HIV was detectable in their cells immediately after the transplant, but the transplanted donor cells replaced the patients' own lymphocytes over time. The amount of HIV DNA in their blood cells decreased and became undetectable, for up to two years now in one patient and three-and-a-half years in the other. CD4s declined in both patients initially, followed by a robust CD4 increase in one patient, and the stabilization and no further decline of CD4s in the other.
Unlike Timothy Ray Brown, the "Berlin Patient," who received cells that were resistant to HIV because they lacked the CCR5 receptor, these patients received cells that were CCR5+. It is believed that the antiretroviral treatment protected the donor cells from becoming infected, leading one researcher to refer to it as "a form of PrEP [pre-exposure prophylaxis] at the cellular level." Further tissue sampling and analytic treatment interruption will need to be conducted to assess the full extent of the reduction of HIV in the reservoir.
At a press conference held the same day these two studies were presented, David Margolis, M.D., University of North Carolina at Chapel Hill, was asked by a reporter about the media's role in reporting on cure advances responsibly and accurately, while at the same time not giving too much hope or creating complacency.
"That's your job," said Margolis. "We are very careful about what we say [as researchers], and we've defined cure several different ways. Different kinds of cure and eradication mean different things to different people, and have different levels of value. Perhaps we should come up with a word, like 'complicated-eradication-chemo-immunotherapy,' to slow people down. But you can't argue with the goal and you can't get there without working on it -- and I can't say how long it will take."

Edited to add a word.
« Last Edit: November 30, 2012, 10:59:02 PM by Rev. Moon »
"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

 


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