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Sangamo reveals successful ZFP results @ ICAAC 2012

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Sangamo held a 3rd quarter earnings conference call on Wednesday and the link below is a transcript of the call.  They talk about the company's HIV phase 2 trials as well as their Huntington's disease research.  There's not a lot of new information here, but they say the Phase 2 trials are progressing well.

"Our lead clinical program SB-728-T, which we are developing as a potential functional cure for HIV is currently in two Phase II studies that are progressing on plan. Both trials are designed to maximize the engraftment of SB-728-T or ZFN-mediated CCR5 disrupted autologous T-cells. We anticipate having preliminary data from these trials in the first half of 2013 and final data in the second half of the year. Meanwhile, we continue to learn from our previous Phase I trials as we analyze data and conduct long-term follow-up on subjects who participated in these studies.

In September, we and our collaborators presented immunologic data from these studies at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy or ICAAC. The data suggests that SB-728-T treatment has the potential to reconstitute the immune system in HIV infected individuals and gives us further insight into the unprecedented positive effects that we have seen on the levels of CD4 T-cells in treated subjects. Id ask Geoff to provide you with more details later in the call." 

You can read the transcript for more info.

Thanks for the update Cosmicdancer. This surely sounds very promising indeed!


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