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Author Topic: STRIBILD - A NEW 1 PILL DRUG side effects  (Read 21946 times)

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Offline gooodman

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  • Posts: 8
STRIBILD - A NEW 1 PILL DRUG side effects
« on: September 04, 2012, 06:06:04 PM »
I would love to here from people who actually tested this new drug. Did you have farts issue like from Complera? Or severe diarrhea? Sleeping problem? Please, help me - I am so badly suffering from Complera..
Aug. 28, 2012 -- The FDA has approved Stribild, the much anticipated once-daily "quad" HIV pill from Gilead Sciences.

The drug combines same two HIV drugs in Truvada, plus elvitegravir, a new HIV drug that attacks HIV in a different way. The fourth component, also new, boosts elvitegravir.

It's the third all-in-one, once-a-day HIV pill. The others are Atripla from Gilead and Bristol Myers, approved in 2006, and Complera from Gilead and Janssen, approved in 2011.

"Over the past decade, co-formulated HIV medicines have simplified therapy for many patients and have become standard of care," Paul Sax, MD, of Brigham and Women's Hospital, says in a Gilead news release.

Stribild is intended for people who have never taken HIV drugs. It should be taken with food.

Stribild carries a "black box" safety warning. In rare cases, the drug causes a buildup of lactic acid in the blood. It can also cause severe liver problems. Both of these side effects can be deadly.


More common side effects include nausea and diarrhea.
[/size]

Offline Pozitively Moving Forward

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #1 on: September 10, 2012, 06:06:00 PM »
.
« Last Edit: September 11, 2012, 07:58:24 PM by Pozitively Moving Forward »
1/11/12 Test Positive HIV CD4 - 434 VL - 58K
2/8/12  CD4 316 VL- 62K (15%)
4/24/12 CD4 - 333 VL-33K (22.3%) 
5/8/12   CD4 - 419 VL - 124  (23.1%)
5/22/12 CD4 - 456 VL - 30  (24.5%)
6/19/12 CD4 - 593 VL - >20 (26.1%)
7/17/12 CD4 - 463 VL - >20 (28.1%)
8/14/12 CD4 - 476 VL - >20 (32.2%)

Offline madbrain

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #2 on: September 10, 2012, 07:11:44 PM »
Hey there gooodman,
I am currently on a double blind clinical trial for Stribild (Quad) and 'Quad2'. 

Doesn't that mean you don't know which med you are on ?
Is it Stribild or is it "Quad2" ?

Your list of side effects seems quite long. Are you sure they are all attributable to the meds ?

If I were you, I would switch to taking it in the evening, I think it might help with your nausea. In my experience with Truvada+Isentress, the med side effects is worse in the morning and/or on empty stomach.
Stribild is supposed to be fairly similar to Truvada+Isentress, at least the drugs are in the same class, and there is a 4th med to extend the half-life of one drug so it can be a once-a-day pill. I take my Truvada+Isentress once-a-day at night though, and all is fine.

Offline Pozitively Moving Forward

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #3 on: September 10, 2012, 09:05:37 PM »
.
« Last Edit: September 11, 2012, 07:58:40 PM by Pozitively Moving Forward »
1/11/12 Test Positive HIV CD4 - 434 VL - 58K
2/8/12  CD4 316 VL- 62K (15%)
4/24/12 CD4 - 333 VL-33K (22.3%) 
5/8/12   CD4 - 419 VL - 124  (23.1%)
5/22/12 CD4 - 456 VL - 30  (24.5%)
6/19/12 CD4 - 593 VL - >20 (26.1%)
7/17/12 CD4 - 463 VL - >20 (28.1%)
8/14/12 CD4 - 476 VL - >20 (32.2%)

Offline Jonnyb

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #4 on: September 18, 2012, 08:53:23 AM »
Hi guys i am new to the forum. I havent been in the clinical trials but i am on day 5 of taking stribild for tge first time (or any hiv med for that matter). I have noticed tgat i am a little more gasy but only a little more. The same with acid reflux. But i am very naucious. I havent thrown up yet but i also havent exactly left the house in a couole of days and yesterday and today i woke up much earlier then usual really naucious. Is anyone else experiencing these side effects? I have never been on antiretroviral treatment before. I heard the first month can be very nausciating so is that what this is? I definately feel like its a little debillitating. Ant info would be appreciated. Thanks everyone!!!

Jonny b

Offline gadawg1979

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #5 on: September 19, 2012, 02:27:48 AM »
On Complera never had the poops... But the farts will peel paint and sleep I have given up on.
Diagnosed March 2012
Initial CD4- 156 VL 200K (started Complera) Genotype test no resistance
First labs on meds CD4- 246 VL 2K Taken after 30 days on Complera
90 Day labs VL 306 No CD4 Drawn
8/21/2012 CD4 474 VL Undetectable (40) %20.6
11/27/2012 CD 4 522 VL Undetectable (40)
2/14/2013 CD 4 464 VL Undetecable (30) 19.6%
6/8/3013 CD 4 528 VL Undetectable (30)
9/24/2013 CD 4 546 VL Undetectable (40)
1/30/2014 CD4 560 VL Undetectable (40) 22 %
6/19/2014 CD4 584 Vl Undetecable (30)

Offline gooodman

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #6 on: September 23, 2012, 12:37:07 AM »
.
Sorry, for some reason I cannot see your answer and I am very interested in your testing experience...

Offline gooodman

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  • Posts: 8
Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #7 on: September 23, 2012, 12:46:49 AM »
Hi guys i am new to the forum. I havent been in the clinical trials but i am on day 5 of taking stribild for tge first time (or any hiv med for that matter). I have noticed tgat i am a little more gasy but only a little more. The same with acid reflux. But i am very naucious. I havent thrown up yet but i also havent exactly left the house in a couole of days and yesterday and today i woke up much earlier then usual really naucious. Is anyone else experiencing these side effects? I have never been on antiretroviral treatment before. I heard the first month can be very nausciating so is that what this is? I definately feel like its a little debillitating. Ant info would be appreciated. Thanks everyone!!!

Jonny b

Sustiva first gave this naucious conditions with nightmares, then Atripla came alone and it has Sustiva in it - so the same effect - you fell naucious for couple of hours and always have a nightmares.. Now you telling that Stribild has the same side effect? For the price they asking - they better come up with higher quality drug. Personaly I have no side effects from Complera bisides it makes me like a leaking gas balloon. You cannot work at the office if you taking Complera. You gonna poison your coworkers!

Offline Ann

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #8 on: September 23, 2012, 08:33:33 AM »
Sorry, for some reason I cannot see your answer and I am very interested in your testing experience...

He edited his posts to remove what he'd written.
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Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline gooodman

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #9 on: September 30, 2012, 09:18:39 PM »
Hi guys i am new to the forum. I havent been in the clinical trials but i am on day 5 of taking stribild for tge first time (or any hiv med for that matter). I have noticed tgat i am a little more gasy but only a little more. The same with acid reflux. But i am very naucious. I havent thrown up yet but i also havent exactly left the house in a couole of days and yesterday and today i woke up much earlier then usual really naucious. Is anyone else experiencing these side effects? I have never been on antiretroviral treatment before. I heard the first month can be very nausciating so is that what this is? I definately feel like its a little debillitating. Ant info would be appreciated. Thanks everyone!!!

Jonny b
Is it amazing - STRIBILD was approved by FDA on August 28, or 2 days plus-minus, and on September 5th you was able to get this brand new drug already taken! God bless America! Please, John your experience is very important for all of us - keep us infomed about your progress! And when you will get your first blood test done, ask your doc to print copy for you and make notes about changes in your numbers. The price for this drug is HUUUUUUUUUGE! So, people want to know how it works.

Offline samothy

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #10 on: November 17, 2012, 05:50:16 PM »
Just started Stribild 9 days ago (Nov 8 2012) and it's my first time on meds. tested positive on 8/31/12 and diagnosed w/ AIDS around 9/15. I've had issues with my appetite, hot farts (lol), headaches, muscle weakness/soreness. The headaches are the most annoying, the headaches and muscle weakness are the only lingering side effects, everything else has gone away.

9/15/12 CD4: 146, VL unknown
10/10/12 CD4: 173, VL: 400,000

we'll see how it works when I get more blood work in December. :)

Offline jimbalaya

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #11 on: November 17, 2012, 06:54:28 PM »
I'm not on stribild but a good friend of mine recently started on Stribild.....he has had very minimal side effects, and in 6 weeks went from a VL of 86,000 to UD....I'm not sure about his CD4 counts.....I'm so jealous....after 4 months on meds, and I am finally down to 289.   

Offline Ricco303

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #12 on: November 18, 2012, 02:31:52 AM »
Hi guys new here first post!
Tested pos October with readings of CD4=5 and VL 273,000,00.
and Hep B chronic with VL of 66,000,000,000 ( that's right million)
Tested again November CD4=56 and VL=102 from stribild.
My Doctor started me on stribild as the first meds. My side affects were nausea, hot and cold sweats, joint pain, and headaches, no gas as some of you experienced. After one month he took me off stribild and put me on the regimen of TRUVADA, RITONAVIR, and PREZISTA and much better. I would avoid taking these meds at night. I have taking both sets of pills an hour or two before bed and have had to throw up both times, its something about how these pills lay on your stomach, may be different for you. I take in the late afternoon 4 FLUCONAZOLE as a precaution.
You will have no appetite but must eat with these pills, so I found DRONABINOL (MARINOL)  10mg pills (THC) prescribed by your doctor does the trick. They say the nausea goes away fairly quickly and I'm in the middle of the second month and still getting nausea like day one.

Hope this helps!

Offline Parker78

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #13 on: November 18, 2012, 02:35:10 PM »
I have been taking Stribild for approximately 3 weeks now.  To date, i have no side effects.  If anyone has any questions about this drug feel free to hit me up.  So far it seems like a great option, but i am yet to get my bloods done since starting so I can't comment on its effectiveness just yet. 

Offline ThomasHopper

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #14 on: November 29, 2012, 05:43:14 PM »
I have been taking Stribild for approximately 3 weeks now.  To date, i have no side effects.  If anyone has any questions about this drug feel free to hit me up.  So far it seems like a great option, but i am yet to get my bloods done since starting so I can't comment on its effectiveness just yet.

I'm in the same boat.  Just started Stribild earlier this week after being on Epzicom/Prezista/Norvir for the past 3 years since diagnosis.  The Prezista regimen did well in keeping me UD, but I had constant abdominal discomfort (always felt like I'd just been punched in the stomach).  My doc suggested the switch, and I'm only on day 4 but the stomach issues have gone away.  I won't know for several weeks how the efficacy is for me, but my doc seems to think it's an excellent drug and just as powerful if not moreso than what I was on previously. 

Offline J.R.E.

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #15 on: November 30, 2012, 12:25:53 PM »

I am not on Stribild, but received this notice today in my email:

"On November 28, 2012, FDA approved a labeling change for the Hepsera (adefovir dipivoxil) package insert to include the following information under Section 5.5, Coadministration with Other Products, and to Section 17.1, Patient Counseling Information/Instructions for Safe Use.

    Hepsera should not be used concurrently with Stribild (elvitegravir/cobicistat/emtricitabine/tenofovir disporoxil fumarate combination tablet).


Hepsera is nucleotide analogue for the treatment of chronic hepatitis B infection, manufactured by Gilead Sciences.
 
The complete, up-to-date Hepsera label may be viewed at Drugs@FDA .
 

Division of Antiviral Products
Food and Drug Administration


http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021449s020lbl.pdf?source=govdelivery

 
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 6/4/14,  t-cells are at 423, Viral load <40

 Current % is at 13% 

  
 62 years young.

Offline WindySkies

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #16 on: December 01, 2012, 12:14:36 PM »
Parker,

What is your meal like that you take the Stribild with?  I'm finishing off my second bottle of Complera right now, and will be switching to Stribild when it runs out.  The Complera has been friendly to me with no side effects, but the 400 calorie requirement has been hard to meet every morning.  I have been on a strict diet and having to eat 400 calories usually over fills me in the morning.

The Gilead site pretty much just says "Stribild should be taken with food."  I wonder how little food?
10/11/2012 Journey Started
10/17/2012 First Labs: VL=57,645  CD4+=730  37%
10/31/2012 Started Complera
11/30/2012 Labs: VL=80  CD4+=929 40%
12/24/2012 Started Stribild

Undetectable since 1/15/13 CD4+= Over 1,400 and 49%

Offline ThomasHopper

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #17 on: December 03, 2012, 09:31:18 PM »
Parker,

What is your meal like that you take the Stribild with?  I'm finishing off my second bottle of Complera right now, and will be switching to Stribild when it runs out.  The Complera has been friendly to me with no side effects, but the 400 calorie requirement has been hard to meet every morning.  I have been on a strict diet and having to eat 400 calories usually over fills me in the morning.

The Gilead site pretty much just says "Stribild should be taken with food."  I wonder how little food?

I'm not Parker, but I had the same discussion with my doctor.  He said around 300 calories would be enough.  I asked him if a protein shake could count as food and he said most likely.  I typically have a bowl of cereal with whole milk as my meal (and have historically with the meds I was on prior to Stribild) and have done well.  I won't know what my results are with Stribild for a couple of weeks, but my doc suggested whatever I ate with my last regimine would work with Stribild. 

Offline Eugene50

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #18 on: December 04, 2012, 07:55:03 PM »
Hi I have been on Stribild for 17 days and have had no side effects my cd4 were 500 and my viral load was 127,000. 17 days later I have a viral load of 300 and cd4 645. I would definitely recommend this pill.

Offline texaninnyc87

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #19 on: December 04, 2012, 08:01:29 PM »
wow! in 17 days? thats incredible. im definitely going to talk to my doctors about stribild.
Dxd: 9/11/12
Blot confirmed: 11/12
12/12 cd4: 280 (20%) vl: 129,000
1/13 $tribild
2/13 cd4: 350 (26%) vl: 80
4/13 cd4: 510 (29%) vl:: 35
6/13cd4 350 (31%) vl: 21
9/13 cd4 492 (30%) vl: ud
12/13 cd4 846 (36%) vl: 100
1/14 cd4 480 (31%) vl: UD
3/14 cd4 650 (33%) vl: UD
6/14 cd4 410 (35%) vl: UD

Offline Eugene50

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #20 on: December 04, 2012, 11:06:49 PM »
Yes 17 days I was sooooooo   Happy my next visit is January 10, 2013 I haven't experienced any side effects from the pill.

Offline ThomasHopper

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #21 on: December 06, 2012, 01:43:38 PM »
I'm on week 3 of Stribild and am thrilled that all of my GI side effects (from the previous regimen) seem to have vanished.  I sure hope my numbers stay good with this drug because the thought of going back to daily stomach aches isn't pleasant. 

Glad to hear others are having success!
« Last Edit: December 06, 2012, 01:47:21 PM by ThomasHopper »

Offline Parker78

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #22 on: December 08, 2012, 11:19:50 AM »
Hi all--my doctor said that any food is ok.  It is not like complera where there is a caloric requirement.  I think the food requirement is more to prevent side effects of nausea and diarrhea (similar to an antibiotic).  My boyfriend just started on Stribild as well and he has had side effects of mild headaches and some diahrrhea.  Overall, he is tolerating it well also.   How is everyone else handling it?

Offline Oneday/undia

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #23 on: December 19, 2012, 06:22:37 PM »
Hi

I being taking Stribild for two weeks and no side effects so far   :). I ll have to wait dor my lab results in a moth
Positive nov/08. Vl 15,000 cd 400
12/08 start treatment ( norvir, truvada,reyataz)
07/12 und/cd 575/42%
12/12 start Stribild
01/13 one month on stribild cd 715/35 %
2/13 725/47% UND
08/13 709/45% UND

Offline RobbyR

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #24 on: December 19, 2012, 06:38:19 PM »
Complera is okay, I've been on it a week..but I am going back to Atripla because I have discovered that my sleep issues and anxiety were not related to either medication. And for me I just don't like to have to calorie-count each time I take it. The Atripla worked for me because I took it at night and I do most of my eating earlier in the day anyway. I don't know anyone personally who is on the Quad/Stribild yet, but am thinking it would be another popular once a day option. The day is coming hopefully when all the regimens will be once a day ones!
Started Atripla August, 2010.

Offline texaninnyc87

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #25 on: December 19, 2012, 06:47:32 PM »
I was really hoping i could get on stribild but my doc is worried about possible kidney problems. she said that until shes seeing me on a regular basis and knows ill come in regularly enough for her to keep an eye on my kidney function she wont prescribe it to me. she was also worried about how new it is. boo! i was really hoping to go on this one as my anxiety issues have ruled out atripla. looks like complera for me! not looking forward to the calorie counting.
Dxd: 9/11/12
Blot confirmed: 11/12
12/12 cd4: 280 (20%) vl: 129,000
1/13 $tribild
2/13 cd4: 350 (26%) vl: 80
4/13 cd4: 510 (29%) vl:: 35
6/13cd4 350 (31%) vl: 21
9/13 cd4 492 (30%) vl: ud
12/13 cd4 846 (36%) vl: 100
1/14 cd4 480 (31%) vl: UD
3/14 cd4 650 (33%) vl: UD
6/14 cd4 410 (35%) vl: UD

Offline WindySkies

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #26 on: December 19, 2012, 07:57:46 PM »
I was really hoping i could get on stribild but my doc is worried about possible kidney problems. she said that until shes seeing me on a regular basis and knows ill come in regularly enough for her to keep an eye on my kidney function she wont prescribe it to me. she was also worried about how new it is. boo! i was really hoping to go on this one as my anxiety issues have ruled out atripla. looks like complera for me! not looking forward to the calorie counting.


Here are some 400 calorie options listed on the Complera site:

2 slices of whole-wheat toast with peanut butter, fresh fruit, and 1 cup of apple juice
Plain bagel with 2 tbsp cream cheese, yogurt, and a banana
2 Pop-Tarts®, yogurt, and 1 cup of apple juice
Dunkin’ Donuts® blueberry muffin and a small coffee with cream
Starbucks® strawberry and blueberry yogurt parfait and a tall latte
2 eggs, 2 strips of bacon, and 2 slices of wheat toast with butter

Roast beef sandwich on a hard roll with mayonnaise, cheese, lettuce, and tomato
2 slices of cheese pizza and 1 can of regular soda
Peanut butter and jelly sandwich on wheat bread, a banana, and 1 cup of skim milk
Subway® 6" classic tuna sub
McDonald’s® hamburger and a side salad with ranch dressing
Veggie burger on a bun with tomato soup and a side salad with dressing

Grilled chicken Caesar salad with dressing
2 cups of spaghetti with marinara sauce and grated parmesan cheese
Salmon with rice and fresh vegetables
1 KFC® Original RecipeTM chicken breast without skin, coleslaw, corn on the cob, and mashed potatoes with gravy
Chipotle® black bean and cheese burrito
Tofu and vegetable stir-fry with brown rice and a side salad with dressing

The site: http://www.complera.com/hiv-treatment-diet/
10/11/2012 Journey Started
10/17/2012 First Labs: VL=57,645  CD4+=730  37%
10/31/2012 Started Complera
11/30/2012 Labs: VL=80  CD4+=929 40%
12/24/2012 Started Stribild

Undetectable since 1/15/13 CD4+= Over 1,400 and 49%

Offline Ann

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #27 on: December 21, 2012, 07:50:29 AM »
Complera is okay, I've been on it a week..but I am going back to Atripla because I have discovered that my sleep issues and anxiety were not related to either medication. And for me I just don't like to have to calorie-count each time I take it.



You might want to give it more than one week - it can take the Sustiva portion of Atripla a while to completely get out of your system and stop causing havoc. There are other once-a-day combos you can take instead of Complera or Atripla.
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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline InChicagoNow

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #28 on: December 24, 2012, 04:29:34 PM »
Hi everyone.  I've been on Stribild for about 3mos now.  I have not had much of an appetite even though I smoke pot everyday.  I get nausea minimally once a day or so.  Like someone said before, right when I wake up and put my feet on the floor.. I get REALLY nauseated... coughing like I'm gonna puke, but I never do.  Then I just smoke some and it goes right away.  Now, I'm out of town for the holidays and I don't have pot with me, so I'm feeling much more nausea now.  I've even thrown up a couple of times since I've been out of town.  I've also been having the cold/hot flashes like I have a fever, but I don't think I actually have.  My sleep patterns are weird.  I find it very hard to stay awake past 6pm.  I sleep my eight hours or so, then get up around 2a-3a.  From that point until about 10a is my best time of the day.  I feel good and productive.  Once I eat lunch and take a nap, I get up feeling blah for the rest of the day.  I just woke up from my nap and walked the dog and now after just shaving and wrapping one present, I feel just crappy.  I think this drug will be tolerable if I can get back home and into my regular routine with smoking pot to counter the nausea.  Just another note:  I have been dealing with depression/anxiety for several years, so although I'm feeling a little more depressed and fatigued I can't for certain attribute it to the Stribild.  My sessions with my therapist have gotten intense and we're bringing up ALOT of pain from the past, so I think waves of depression are normal when someone is processing years of "stuff".  I guess I'll stick with this for now.  I'm unemployed, so it's much better to pay for one med than two (I was on Issentress/Truvada) before that basically from the day that Issentress was approved and never had one side effect whatsoever.  I was undetectable before and still am.  CD4 was 942 in March, 2012 and 1372 in Oct, 2012.
« Last Edit: December 24, 2012, 04:35:52 PM by InChicagoNow »
"Be kind, for everyone you meet is fighting a hard battle."

Offline RobbyR

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #29 on: December 24, 2012, 08:39:29 PM »
I'm glad there is another one pill once a day option out there now, hopefully soon, all hiv meds will be one pill. So much easier. I take Atripla and it's worked well for me. I tried Complera and I actually thought it made my sleep issues WORSE! I got hardly any sleep on Complera! Plus I didn't like the calorie counting it required, that was way too annoying. And I felt weird on it, so I went back to Atripla! I can't comment on Stribild because I don't know enough about it, nor do I know anyone who's on it now. But I would say if the negatives you feel on it outweigh the positives, change your meds. Don't settle. Find a regimen that has the least negatives for you. Everyone's different.
Started Atripla August, 2010.

Offline Nasty Weather

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #30 on: December 30, 2012, 08:45:58 PM »
I just came off a 1 year study where I took 5 drugs and 1 placebo with no side effects and now I  have been on Stribild for 10 days now, with no complaints, I had a colonoscopy the other day so I had to take it while fasting and had no problems.


Offline Parker78

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #31 on: January 03, 2013, 10:52:13 AM »
Hi all--my doctor said that any food is ok.  It is not like complera where there is a caloric requirement.  I think the food requirement is more to prevent side effects of nausea and diarrhea (similar to an antibiotic).  My boyfriend just started on Stribild as well and he has had side effects of mild headaches and some diahrrhea.  Overall, he is tolerating it well also.   How is everyone else handling it?


Just a stribild update.  I have now been on Stribild for approximately 1 1/2 months.   My viral load went from 25k  to UD in that short period.  My CD4 is currently 594.   Still no side effects.  I recommend this drug for first time treatment users.

Offline texaninnyc87

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #32 on: January 07, 2013, 06:02:37 PM »
Convinced my doc today to let me try Stribild! Looks like ill be taking my first step towards UD tomorrow.  ;D
Ill keep you guys updated about side effects/efficacy and all that.
So glad I convinced her! This really was my top choice in terms of pills. Apparently my strain is resistant to Sustiva, so even without my anxiety issues Atripla was out of consideration. Anyone had any skin issues with Stri? I have crazy sensitive skin so I'm really hoping to avoid any kind of nasty rash situation.
Dxd: 9/11/12
Blot confirmed: 11/12
12/12 cd4: 280 (20%) vl: 129,000
1/13 $tribild
2/13 cd4: 350 (26%) vl: 80
4/13 cd4: 510 (29%) vl:: 35
6/13cd4 350 (31%) vl: 21
9/13 cd4 492 (30%) vl: ud
12/13 cd4 846 (36%) vl: 100
1/14 cd4 480 (31%) vl: UD
3/14 cd4 650 (33%) vl: UD
6/14 cd4 410 (35%) vl: UD

Offline texaninnyc87

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #33 on: January 09, 2013, 09:39:20 PM »
why doesnt anything in this thread mention how HUGE stribild pills are!? jesus! i just got my first bottle and will take my first one tomorrow morning (gulp) and couldnt resist looking inside. note, these are the first pills i will ever be taking for HIV. are they all that enormous??? or is it just because stribild is 4 pills in one? i had to wait a few days for them to get it in stock, which is kind of worrying but i guess ill start asking for refills a week or so before i need them? not sure how that works. also the girl at the pharmacy said that my insurance (ADAP) didnt cover the vitamin D and B12 pills my doc prescribed so im gonna have to figure out whats up with that. cheers to my last day med-free! (that is if i can actually manage to choke down one of those horse pills..."
Dxd: 9/11/12
Blot confirmed: 11/12
12/12 cd4: 280 (20%) vl: 129,000
1/13 $tribild
2/13 cd4: 350 (26%) vl: 80
4/13 cd4: 510 (29%) vl:: 35
6/13cd4 350 (31%) vl: 21
9/13 cd4 492 (30%) vl: ud
12/13 cd4 846 (36%) vl: 100
1/14 cd4 480 (31%) vl: UD
3/14 cd4 650 (33%) vl: UD
6/14 cd4 410 (35%) vl: UD

Offline Parker78

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #34 on: January 09, 2013, 09:46:29 PM »
why doesnt anything in this thread mention how HUGE stribild pills are!? jesus! i just got my first bottle and will take my first one tomorrow morning (gulp) and couldnt resist looking inside. note, these are the first pills i will ever be taking for HIV. are they all that enormous??? or is it just because stribild is 4 pills in one? i had to wait a few days for them to get it in stock, which is kind of worrying but i guess ill start asking for refills a week or so before i need them? not sure how that works. also the girl at the pharmacy said that my insurance (ADAP) didnt cover the vitamin D and B12 pills my doc prescribed so im gonna have to figure out whats up with that. cheers to my last day med-free! (that is if i can actually manage to choke down one of those horse pills..."

My trick is to take it with food--LITERALLY.  Chew up a a half piece of bread and actually swallow it down with the bread.  You wont even notice it going down.  Another thing is to try with soda as opposed to water--the bubbles make it easier.

Offline buginme2

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #35 on: January 09, 2013, 09:50:21 PM »
atripla, stribild, and complera are all similar in size.  You just get used to it.  Its really no bigger than a lot of multi-vitamins. 

Offline texaninnyc87

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #36 on: January 09, 2013, 10:21:11 PM »
thats why i like the gummy vitamins! maybe i'll write to Gillead about making a gummy option for Stribild.  :P
Dxd: 9/11/12
Blot confirmed: 11/12
12/12 cd4: 280 (20%) vl: 129,000
1/13 $tribild
2/13 cd4: 350 (26%) vl: 80
4/13 cd4: 510 (29%) vl:: 35
6/13cd4 350 (31%) vl: 21
9/13 cd4 492 (30%) vl: ud
12/13 cd4 846 (36%) vl: 100
1/14 cd4 480 (31%) vl: UD
3/14 cd4 650 (33%) vl: UD
6/14 cd4 410 (35%) vl: UD

Offline mpositive

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #37 on: January 10, 2013, 06:23:05 AM »
I just Started Stribild a  couple of days ago.  I was on Isentress/Selzentry/Truvada, but I am preparing for a VSG (Vertical Sleeve Gastrectomy) and need to reduce my load of pills that cannot be crushed. 
I have had some headaches, but I think that may be due to the stress of it all.  Otherwise, easy peasy. 
Truth be told, I want to get Selzentry back into the mix after the surgery, I think Selzentry is an incredible medication. 
I only wish I could crush these pills for my surgery.....baaahhh.
Good luck on Stribild, it's like Isentress on crack...lol.

Offline texaninnyc87

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #38 on: January 14, 2013, 01:04:51 PM »
i think the side effects are beginning. I'm on day 5 of stribild. Mild nausea. Vivid dreams. Not sure if the dreaming is med related? They seem a lot more vivid and crazy since starting but that could just be my imagination or something to do with the fact that ive drastically cut back on drinking (almost all together) in the past few weeks. Last night I woke up FREEZING, put on about 4 blanket, shivered for an hour before getting back to sleep. Gradually stripped the blankets off during the night. Woke up drenched in sweat. Ugh! I was scared for a second I was coming down with that mega flu epidemic sweeping the nation (even though i got the shot) but I think its just the stribild. None of these effects have been too bad at all but I must admit i was hoping for none...anyone else with the vivid dreams? i know theyre usually associated with atripla but i've read they are still likely with stribild, just less so.
Dxd: 9/11/12
Blot confirmed: 11/12
12/12 cd4: 280 (20%) vl: 129,000
1/13 $tribild
2/13 cd4: 350 (26%) vl: 80
4/13 cd4: 510 (29%) vl:: 35
6/13cd4 350 (31%) vl: 21
9/13 cd4 492 (30%) vl: ud
12/13 cd4 846 (36%) vl: 100
1/14 cd4 480 (31%) vl: UD
3/14 cd4 650 (33%) vl: UD
6/14 cd4 410 (35%) vl: UD

Offline buginme2

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #39 on: January 15, 2013, 03:07:42 PM »
The dreams are the best part, free entertainment.

Give it time, your body will get used to it and these little naggin effects will go away.

Offline texaninnyc87

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #40 on: January 16, 2013, 12:16:50 AM »
i kind of like them. last night i dreamt i was walking through the forest with all my friends. we got to this serene beach and saw these huge boats floating in the distance. slowly they grew larger and we realized they were giant houses! they weren't just any houses, but each of our dream houses! they floated up to the shore and walked (they could walk) up to the person they belonged to who in turn told them where to settle down. my friends and i lived together in a tiny community of dream houses on a beautiful beach next to a serene forest.   ;D

i guess that one was pretty nice. i also had a dream that aliens were biting my hands through my sheets and woke up terrified...
Dxd: 9/11/12
Blot confirmed: 11/12
12/12 cd4: 280 (20%) vl: 129,000
1/13 $tribild
2/13 cd4: 350 (26%) vl: 80
4/13 cd4: 510 (29%) vl:: 35
6/13cd4 350 (31%) vl: 21
9/13 cd4 492 (30%) vl: ud
12/13 cd4 846 (36%) vl: 100
1/14 cd4 480 (31%) vl: UD
3/14 cd4 650 (33%) vl: UD
6/14 cd4 410 (35%) vl: UD

Offline texaninnyc87

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #41 on: January 18, 2013, 01:41:11 PM »
ANybody else feel a weird kind of high a few hours after taking stribild? it doesnt last very long. i havent read anything about this. should i expect is to go away? ive only been taking them for a week.
Dxd: 9/11/12
Blot confirmed: 11/12
12/12 cd4: 280 (20%) vl: 129,000
1/13 $tribild
2/13 cd4: 350 (26%) vl: 80
4/13 cd4: 510 (29%) vl:: 35
6/13cd4 350 (31%) vl: 21
9/13 cd4 492 (30%) vl: ud
12/13 cd4 846 (36%) vl: 100
1/14 cd4 480 (31%) vl: UD
3/14 cd4 650 (33%) vl: UD
6/14 cd4 410 (35%) vl: UD

Offline Oneday/undia

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #42 on: January 19, 2013, 12:12:09 PM »
No side effects so far :) but i wouldn't mind feeling high ;D
Positive nov/08. Vl 15,000 cd 400
12/08 start treatment ( norvir, truvada,reyataz)
07/12 und/cd 575/42%
12/12 start Stribild
01/13 one month on stribild cd 715/35 %
2/13 725/47% UND
08/13 709/45% UND

Offline texaninnyc87

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #43 on: January 19, 2013, 12:14:54 PM »
it's so subtle it could be in my head, so im not really even sure if its real or not...
Dxd: 9/11/12
Blot confirmed: 11/12
12/12 cd4: 280 (20%) vl: 129,000
1/13 $tribild
2/13 cd4: 350 (26%) vl: 80
4/13 cd4: 510 (29%) vl:: 35
6/13cd4 350 (31%) vl: 21
9/13 cd4 492 (30%) vl: ud
12/13 cd4 846 (36%) vl: 100
1/14 cd4 480 (31%) vl: UD
3/14 cd4 650 (33%) vl: UD
6/14 cd4 410 (35%) vl: UD

Offline leatherman

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #44 on: January 19, 2013, 02:09:44 PM »
ive only been taking them for a week.
if after 4 to 6 weeks this is still happening then you might want to speak to your doctor about it. Until then remember that your body is going through a lot of changes as your VL is dropping as the HIV is dying, as your CD4s and immune system are recovering, and as your body is adjusting to the new chemicals/medications that you've introduced into your system.

Remember too, it could be worse. LOL not to diminish the effect you're having or that if it continues you should seek medical help; but You could be barfing or having the runs as your body adjusts. A weird kind of high for a few hours isn't the worst thing, if you can plan to take it in stride.  ;)
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline Casinokiwi

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #45 on: February 06, 2013, 12:07:18 AM »
ANybody else feel a weird kind of high a few hours after taking stribild? it doesnt last very long. i havent read anything about this. should i expect is to go away? ive only been taking them for a week.

Yes, I am feeling it right now.  I have been on stribild since early October and my viral load went from 50 million to undetectable in a 45 days.  My doctor was doing trials with the drug and said he never saw anything like it.  The only down side is that my insurance company is making me get it through the mail now.  I am not the best source for this since I have not been on any other meds but the results seem to be good.

I do have one question...  I met someone who has killer t-cells and the basically maintain undetectable viral loads without medication.  How would I know if I have these t cells if I rushed on medication?


Offline Buckmark

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #46 on: February 06, 2013, 01:33:17 AM »
Yes, I am feeling it right now.  I have been on stribild since early October and my viral load went from 50 million to undetectable in a 45 days.  My doctor was doing trials with the drug and said he never saw anything like it.  The only down side is that my insurance company is making me get it through the mail now.  I am not the best source for this since I have not been on any other meds but the results seem to be good.

I do have one question...  I met someone who has killer t-cells and the basically maintain undetectable viral loads without medication.  How would I know if I have these t cells if I rushed on medication?

You had a viral load of 50 million?  You're lucky you weren't consumed -- I've never heard of anyone having a viral load that high.  I'm not even sure the viral load test can measure that high. 
"Life in Lubbock, Texas, taught me two things:
     One is that God loves you and you're going to burn in hell.
     The other is that sex is the most awful, filthy thing on earth and you should save it for someone you love."
- Butch Hancock, Musician, The Flatlanders

Offline oksikoko

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #47 on: February 06, 2013, 02:09:28 AM »
"Yes, I am feeling it right now. "

Would you please call my doctor and tell him that I'm not crazy. ;)
Code: [Select]
2013-10-03:                ☣ VL (=) undetectable ☣ CD4 (+) 1105
2013-05-23:                ☣ VL (=) undetectable ☣ CD4 (-) 945
2013-02-25:                ☣ VL (-) undetectable ☣ CD4 (+) 1123
2012-12-16: Enter Stribild
2012-11-20: HIV+           ☣ VL (→) 132,683      ☣ CD4 (→) 920
2012-04-01: HIV-
Dates in this signature file conform to ISO 8601. ;-)

Offline oksikoko

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #48 on: February 06, 2013, 02:18:58 AM »
I do have one question...  I met someone who has killer t-cells and the basically maintain undetectable viral loads without medication.  How would I know if I have these t cells if I rushed on medication?

Sorry - I meant to say this in my other post. Re: the killer t-cells. I've heard about Stanford creating something like this in a lab (http://www.aidsmeds.com/articles/Stanford_genes_1667_23396.shtml), but I haven't heard of it existing in nature. I also remember hearing a lot about people who just have a natural immunity and never get infected even after repeated exposure. BUT this is a very small number of people if they really exist at all, so the probability that you have some sort of natural defense is extremely low. I don't know who you would talk to about a test for that, but really, don't do any home experiments to "see what happens".

Like Buckmark said, yours is also the highest viral load that I've heard of, but I'm new at this. Mine was 132,000+, when I was diagnosed, and at the time, I thought that was ridiculously high... Are you sure you didn't move a comma over accidentally on your labs?

I would think if you had any sort of natural killer t-cells, your viral load would never have gotten that high, which is even more reason to avoid any home experiments... 
Code: [Select]
2013-10-03:                ☣ VL (=) undetectable ☣ CD4 (+) 1105
2013-05-23:                ☣ VL (=) undetectable ☣ CD4 (-) 945
2013-02-25:                ☣ VL (-) undetectable ☣ CD4 (+) 1123
2012-12-16: Enter Stribild
2012-11-20: HIV+           ☣ VL (→) 132,683      ☣ CD4 (→) 920
2012-04-01: HIV-
Dates in this signature file conform to ISO 8601. ;-)

Offline buginme2

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Re: STRIBILD - A NEW 1 PILL DRUG side effects
« Reply #49 on: February 06, 2013, 02:58:08 AM »


I do have one question...  I met someone who has killer t-cells and the basically maintain undetectable viral loads without medication.  How would I know if I have these t cells if I rushed on medication?

Everyone has "killer t-cells."  CD8 T cells are called "killer T-cells" because they recognize cells that have been infected by viruses, attatch themselves to the infected cell, and kill it.  However, this doesnt work so well with HIV infected cells.

I think the person you met meant to say they were a long term non-progressor.

There are a small group of HIV infected people that can maintain an undetectable viral load without the need for going on medication.  They are called long term non-progressors (or elite controllers).  There is a lot of research going on to determine how these people are able to control their HIV infection on their own.  Hopefully if researchers can figure out exactly how their immune system can control their infection they can benefit everyone else.

So how can you tell if you are a long term non-progressor if you start medication right away?  Well you cant.  However, chances are you are not.  Long term non progressors account for a small amount of patients maybe 1%.  Which means there is a 99% chance that your not one.  Since you had a viral load in the millions, you probably made the right choice starting meds.

 


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