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Author Topic: Stem Cell transplatation for ED  (Read 1261 times)

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Offline Mishma

  • Member
  • Posts: 190
    • Marquis de Vauban
Stem Cell transplatation for ED
« on: August 09, 2012, 03:19:21 PM »
Try keeping a condom on with ED.


Review

Nature Reviews Urology 9, 435-447 (August 2012) | doi:10.1038/nrurol.2012.111
Corrected online: 26 June 2012

http://www.nature.com/nrurol/journal/v9/n8/abs/nrurol.2012.111.html?lang=en?WT.ec_id=NRUROL-201208

Subject Category: Sexual dysfunction

Stem cell therapy for voiding and erectile dysfunction
Martin Vaegler, Andrew T. Lenis, Lisa Daum, Bastian Amend, Arnulf Stenzl, Patricia Toomey, Markus Renninger, Margot S. Damaser & Karl-Dietrich Sievert  About the authors

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Abstract
Voiding dysfunction comprises a variety of disorders, including stress urinary incontinence and overactive bladder, and affects millions of men and women worldwide. Erectile dysfunction (ED) also decreases quality of life for millions of men, as well as for their partners. Advanced age and diabetes are common comorbidities that can exacerbate and negatively impact upon the development of these disorders. Therapies that target the pathophysiology of these conditions to halt progression are not currently available. However, stem cell therapy could fill this therapeutic void. Stem cells can reduce inflammation, prevent fibrosis, promote angiogenesis, recruit endogenous progenitor cells, and differentiate to replace damaged cells. Adult multipotent stem cell therapy, in particular, has shown promise in case reports and preclinical animal studies. Stem cells also have a role in urological tissue engineering for ex vivo construction of bladder wall and urethral tissue (using a patient's own cells) prior to transplantation. More recent studies have focused on bioactive factor secretion and homing of stem cells. In the future, clinicians are likely to utilize allogeneic stem cell sources, intravenous systemic delivery, and ex vivo cell enhancement to treat voiding dysfunction and ED.
2016 CD4 25% UD (less than 20). 27+ years positive. Isentress, Truvada, Acyclovir, Clonazepam, Zolpidem, Bupropion, Lisinopril, Pravastatin, Quetiapine, Doxcycline, Testosterone, Suatriptan/Naproxen, Restasis, Dorzolamide, Latanoprost, Asprin, lortab, Levothyroxine, Fioricet, Restasis, Triamclinolone, Nitrostat.

 


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