Quantcast

Subscribe to:
POZ magazine
Newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr Instagram
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
December 28, 2014, 03:10:17 PM

Login with username, password and session length


Members
  • Total Members: 24315
  • Latest: Eb39
Stats
  • Total Posts: 650597
  • Total Topics: 49677
  • Online Today: 192
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: First Viral Load "Blip"  (Read 3664 times)

0 Members and 1 Guest are viewing this topic.

Offline Lou-ah-vull

  • Member
  • Posts: 954
First Viral Load "Blip"
« on: July 13, 2012, 01:37:25 PM »
Well, after five plus years of "undetectable" viral load, I have my first "blip" of 40.  The doctor wants me to recheck in 3 months.  (I have been having six months checks for quite some time now.)

The good news is that for the first time in six years I have normal triglycerides:  132.  Normal cholesterol = 118.  Highest HDL in my life = 49.  I am pretty sure the large doses on niacin daily are the game changer here.

Two concerns.  My blood sugar was ungodly high at 241.  I will see my internist next week to be evaluated for treatment for diabetes.  I have been on the border of this with blood sugar for the past three years.  Also my C-Reactive Protein was way off at 20.6. (it should never be higher than 4 and has always been low with me.)  My ID doctor wants to recheck this too in three months after evaluation for diabetes.

The blip was unexpected but I have known for some time I was at risk for type 2 diabetes.  I will learn more next week.  Aging ain't fun! 

The blip of course has my attention, but thankfully I have read about them so much on here the past years and I know that one test is only enough to heighten concern.  I am fortunate my doctors are pretty aggressive about this.

Curious if any of you know what kind of treatment I will be facing about the blood sugar.  A bit surprised that with triglycerides normal for the first time since diagnosis that my blood sugar has spiked so high.  I always thought they were somehow related.

Gary
Diagnosed Oct. 2005
10/05:  367 (26.2%), 24556 VL
01/06:  344 (24.6%), 86299 VL
04/06:  374 (22.0%), 87657 VL
05/06:  Began HAART 05/15/06, Combivir/Kaletra
07/06:  361 (27.8%), 1299 VL
10/06:  454 (32.4%), 55 VL
01/07:  499 (38.4%), UD
02/07:  Switched to Atripla 2/8/07
04/07:  566 (37.7%), UD
08/07:  761 (42.3%), UD
06/08:  659 (47.1%), UD
01/09:  613 (43.8%), UD
07/09:  616 (47.4%), UD
01/10:  530 (44.2%), UD
07/10:  636 (48.9%), UD
01/11:  627 (48.2%), UD
07/11:  840 (52.5%), UD
01/12:  920 (51.1%), UD
07/12:  857 (50.4%), 40
10/12:  UD
01/13:  710 (47.3%), UD
07/13:  886 (49.2%), UD
01/14:  985 (46.9%), UD
06/14:  823 (47.2%), UD

Offline buginme2

  • Member
  • Posts: 3,309
Re: First Viral Load "Blip"
« Reply #1 on: July 13, 2012, 02:52:11 PM »
The viral load of 40 is still undetectable in my book.  Based on your signature line your numbers are great.

Diabetes. A blood sugar result of 240 is pretty high.  Was this a fasting blood test or a random test?  If you ate before giving blood it could account for some of the elevation.

If you do have Diabetes step one would be evaluating your diet.  How is your diet? 

A common medication for diabetes is metformin.  Even with diet changes they will probably start you on it.
Don't be fancy, just get dancey

Offline Lou-ah-vull

  • Member
  • Posts: 954
Re: First Viral Load "Blip"
« Reply #2 on: July 13, 2012, 05:57:51 PM »
It was 12 hours fasting.  Over the last two years, I have been between 116 and 131 on blood sugar after fasting blood draws.  At the same time, I had high triglycerides, sometimes over 500, always over 330.  This test is the first time since diagnosis that I have had normal lipids, but this very high blood sugar test is troubling.  I have my annual physical in ten days and as supposed to have blood work again on Wednesday.  My internist is evaluating this information to see what, if any, blood work he wants to order (I am pretty sure he is going to want to test my blood sugar again.)

I know not to worry about that "blip" (although to be honest, I blanched when I first saw it) but I am concerned about the possibility of diabetes.

To answer your diet question, there is considerable room for change.  I am overweight by about 18 lbs and have made no attempt to regulate simple carbs and sugars.  I feel a "major change" coming on!

Gary
Diagnosed Oct. 2005
10/05:  367 (26.2%), 24556 VL
01/06:  344 (24.6%), 86299 VL
04/06:  374 (22.0%), 87657 VL
05/06:  Began HAART 05/15/06, Combivir/Kaletra
07/06:  361 (27.8%), 1299 VL
10/06:  454 (32.4%), 55 VL
01/07:  499 (38.4%), UD
02/07:  Switched to Atripla 2/8/07
04/07:  566 (37.7%), UD
08/07:  761 (42.3%), UD
06/08:  659 (47.1%), UD
01/09:  613 (43.8%), UD
07/09:  616 (47.4%), UD
01/10:  530 (44.2%), UD
07/10:  636 (48.9%), UD
01/11:  627 (48.2%), UD
07/11:  840 (52.5%), UD
01/12:  920 (51.1%), UD
07/12:  857 (50.4%), 40
10/12:  UD
01/13:  710 (47.3%), UD
07/13:  886 (49.2%), UD
01/14:  985 (46.9%), UD
06/14:  823 (47.2%), UD

Offline newt

  • Member
  • Posts: 3,887
  • the one and original newt
Re: First Viral Load "Blip"
« Reply #3 on: July 13, 2012, 09:11:18 PM »
Erm, look, 40 is not a blip on any viral load test, whatever your doc says. So rest easy.

- matt
"The object is to be a well patient, not a good patient"

Offline NY2011

  • Member
  • Posts: 141
Re: First Viral Load "Blip"
« Reply #4 on: July 13, 2012, 09:38:07 PM »
I agree. Don't make the next three months hell for yourself.  Your CD4 count is good and VL of 40 could very well be a blip.  I'm still fairly new to this, but after reaching undetectable on Atripla for the first time, my Cd4 went up to 140 the second time, and then back down to undetectable again two months later.

Thanks to you, Lou-ah-vil, I requested a hs-CRP test, and it came back at 4.1 which is the low end of high. I've been told that the number by itself doesn't mean much, but with a lipid panel and your blood pressure stats, I understand that it may be an indicator. 

I'm curious about your success with the niacin supplement that you recommended. What is your suggested dosage?  My meds are giving me high cholesterol numbers. 
« Last Edit: July 13, 2012, 09:46:45 PM by NY2011 »
10/26/2011 - SEROCONVERSION (hi fever+rash)
10/31/2011 - CD4= 154  VL>500,000 
10/31/2011 - started on Truvada+Prezista+Norvir
12/14/2011 - CD4= 750 VL=6412 (45%)
01/27/2012 - switched to Atripla
04/23/2012 - CD4=1,221 VL= 140  (47%)
06/22/2012 - CD4=1,224 VL= ud    (49%)
12/18/2012 - CD4=1,031 VL= ud    (51%)
09/16/2013 - CD4=1,151 VL= ud   ( 49%)
03/26/2014 - CD4=1,050 VL= ud
11/25/2014 - CD4=1,335 VL= ud

Offline Lou-ah-vull

  • Member
  • Posts: 954
Re: First Viral Load "Blip"
« Reply #5 on: July 13, 2012, 11:18:03 PM »
I take six 500 mg tablets of niacin a day.  Two in the morning, two in the middle of the day, and two at bedtime.  30 minutes before taking niacin, I take either one full dose aspirin or ibuprofen.  This is necessary to prevent/reduce flushing (harmless, but highly uncomfortable.)  Nothing else has worked the way niacin has worked especially to bring down my very high triglycerides and to raise my HDL cholesterol.

Gary
Diagnosed Oct. 2005
10/05:  367 (26.2%), 24556 VL
01/06:  344 (24.6%), 86299 VL
04/06:  374 (22.0%), 87657 VL
05/06:  Began HAART 05/15/06, Combivir/Kaletra
07/06:  361 (27.8%), 1299 VL
10/06:  454 (32.4%), 55 VL
01/07:  499 (38.4%), UD
02/07:  Switched to Atripla 2/8/07
04/07:  566 (37.7%), UD
08/07:  761 (42.3%), UD
06/08:  659 (47.1%), UD
01/09:  613 (43.8%), UD
07/09:  616 (47.4%), UD
01/10:  530 (44.2%), UD
07/10:  636 (48.9%), UD
01/11:  627 (48.2%), UD
07/11:  840 (52.5%), UD
01/12:  920 (51.1%), UD
07/12:  857 (50.4%), 40
10/12:  UD
01/13:  710 (47.3%), UD
07/13:  886 (49.2%), UD
01/14:  985 (46.9%), UD
06/14:  823 (47.2%), UD

Offline sanitex

  • Member
  • Posts: 388
Re: First Viral Load "Blip"
« Reply #6 on: July 14, 2012, 01:04:48 AM »

H! LOu-ah-vull  anyway i don't have much to say but a bit contribution and it work
for me. i even wrote to Dr Nelson  at thebody .com he comfirmed it .
so try to buy Apple cider vinegar brand name (Bragg)drink it everyday three times
 a day you'll see the impact even your cholesterol,LDl,HDl,triglycerides ,will improve better than before,for glucose that's for sure within one week it will subside  your level to normal thakx
27/12/07 cd4 20 vl 1million
10/4 /08 cd4 86 vl 63
1/7/08  cd4 186 vl undetectable
16/10/08 cd4 196 vl undet
23/1/09 cd4 248 vl un
10/9/11 cd4 418 vl <40 %22
13/12/11 cd4 410 vl undet 23%
24/2/12 cd4 545 vl undet 26%
on 22/2/12 change truvada to Recovir-EM
due to no stock on Truvada.
10/9/11 cd4 418 vl <40 %22
7/7/12 cd4 359 vl <40 22%
23/8/12 cd4 400 vl <40 23%,
testosterone test 7.5 ng/ml and
thyroid (TSH)1.32 ulu/ml creatinine.eGFR blck 1.5 all fasting test morning.
13/12/2012 cd4 523 24% vl <40
18/3/2013 cd4  513  23% vl <40
regimen ATRIPLA
03/8/2013 cd4 429 22% vl <40
13/11/2013 cd4 455 23% vl <40
Anti-HBs test (quantitative ) Anti-HBs positive
Titer 16.95 mlu/ml <10.00
22/3/14 cd4 396 vl <40 24%
24/7/14 change to Teevir
24/9/14 cd4 517 vl <40 22%

Offline jkinatl2

  • Member
  • Posts: 6,007
  • Doo. Dah. Dipp-ity.
Re: First Viral Load "Blip"
« Reply #7 on: July 14, 2012, 03:01:06 AM »
H! LOu-ah-vull  anyway i don't have much to say but a bit contribution and it work
for me. i even wrote to Dr Nelson  at thebody .com he comfirmed it .
so try to buy Apple cider vinegar brand name (Bragg)drink it everyday three times
 a day you'll see the impact even your cholesterol,LDl,HDl,triglycerides ,will improve better than before,for glucose that's for sure within one week it will subside  your level to normal thakx

Yes. I am sure that drinking vinegar will be the solution.

"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

Welcome Thread

Offline Lou-ah-vull

  • Member
  • Posts: 954
Re: First Viral Load "Blip"
« Reply #8 on: July 14, 2012, 04:14:11 PM »
Egad.  Right up their with cod liver oil.  Thanks...but no thanks!

Diagnosed Oct. 2005
10/05:  367 (26.2%), 24556 VL
01/06:  344 (24.6%), 86299 VL
04/06:  374 (22.0%), 87657 VL
05/06:  Began HAART 05/15/06, Combivir/Kaletra
07/06:  361 (27.8%), 1299 VL
10/06:  454 (32.4%), 55 VL
01/07:  499 (38.4%), UD
02/07:  Switched to Atripla 2/8/07
04/07:  566 (37.7%), UD
08/07:  761 (42.3%), UD
06/08:  659 (47.1%), UD
01/09:  613 (43.8%), UD
07/09:  616 (47.4%), UD
01/10:  530 (44.2%), UD
07/10:  636 (48.9%), UD
01/11:  627 (48.2%), UD
07/11:  840 (52.5%), UD
01/12:  920 (51.1%), UD
07/12:  857 (50.4%), 40
10/12:  UD
01/13:  710 (47.3%), UD
07/13:  886 (49.2%), UD
01/14:  985 (46.9%), UD
06/14:  823 (47.2%), UD

Offline eric48

  • Member
  • Posts: 1,211
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
Re: First Viral Load "Blip"
« Reply #9 on: July 15, 2012, 04:19:36 PM »
The viral load of 40 is still undetectable in my book.

I recently had a Research Hosptal VL trest in facility that measures down to 40. (the other lab I use goes down to 20)

the lab results was interestingly written is a very instrumentally correct way:

VL : origin: plasma
VL <40
Comment: the VL was detectable but below the level of quantication (40 copies/mL)


I will ask my doc if he has ever seen comments like : VL was undetectable
This would certainly happen if the technician verifies his machine with and un-infected blood sample, which, I would think may be part of instrumental procedure.

Many people misuse the term UD, they should either use < XX or BLQ

Eric
(who also misuses the term UD for anything below 50 or similar)
NVP/ABC/3TC/... UD (non-infectious) ; CD4 > 1000; CD4/CD8 ~ 2.0   stock & donations : 6 months (2013: FOTO= 5d. ON 2d. OFF ; 2014: Clin. Trial NCT02157311 = 4d. ON, 3d. OFF)

Offline bocker3

  • Member
  • Posts: 3,459
  • You gotta enjoy life......
Re: First Viral Load "Blip"
« Reply #10 on: July 15, 2012, 06:40:40 PM »
I don't think that the term "undetectable" is misused, rather it is misunderstood.

If the assays lower end is 40 (or 20 or 50 or whatever) -- "undetectable" means that there is insufficienct virus to be detected by this assay.  Whether it is "present" in some volume below the assay's limit or is actually zero, is "unknonw", because you can't trust any reading below the assay's limit.  It might "read" 36 and actually be 0.  There is a reason for the low end limit -- it is the limit that can be "trusted".

Gary --
Hang in there -- I see no real difference between 40 and <40.  Of course, that is easier for me to say than you to internalize.
Looking forward to seeing you in a couple of weeks and hearing all about Alaska.

Hugs,
Mike
Atripla - Started 12/05
Reyataz/Norvir - Added 6/06
Labs - Pre-Meds
Sep05 T=350/25% VL98,559
Nov05 288/18%  47,564
Current Labs
May2013 691/31% <20

Online leatherman

  • Member
  • Posts: 6,344
  • Google and HIV meds are Your Friends
Re: First Viral Load "Blip"
« Reply #11 on: July 15, 2012, 06:55:56 PM »
I see no real difference between 40 and <40
considering just about 2 or 3 yrs ago "undetectable" was considered less than 200; and just a couple of yrs before than undetectable was <400**, IMHO anything <100 is still not much of anything these days. ;) :D as has been mentioned "undetectable" doesn't mean "no HIV"; it just means below the limits of this test.

(**in both cases because that's as low as the test could score. Now some tests score <20 and some are <10!!)
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline Lou-ah-vull

  • Member
  • Posts: 954
Re: First Viral Load "Blip"
« Reply #12 on: July 15, 2012, 07:13:39 PM »
My assay goes as low as 20.  I am not that concerned about the viral load (although, you are correct that "I don't like it') but I am quite worried about my blood sugar and the possibility of the diabetes diagnosis.  I am not sure what "life changing" circumstances await me if I have type 2 diabetes.  Trying to read about it now, but like anything else medical, you can really get yourself worried when you start researching on your own on the internet. 

I am guessing they are going to retest by fasting blood sugar this week and then take the next step.  It's that "next step" that is worrying me....

Does anyone know much about type 2 diabetes and more importantly, how it relates to HIV treatment?

I always appreciate the support!

Gary
Diagnosed Oct. 2005
10/05:  367 (26.2%), 24556 VL
01/06:  344 (24.6%), 86299 VL
04/06:  374 (22.0%), 87657 VL
05/06:  Began HAART 05/15/06, Combivir/Kaletra
07/06:  361 (27.8%), 1299 VL
10/06:  454 (32.4%), 55 VL
01/07:  499 (38.4%), UD
02/07:  Switched to Atripla 2/8/07
04/07:  566 (37.7%), UD
08/07:  761 (42.3%), UD
06/08:  659 (47.1%), UD
01/09:  613 (43.8%), UD
07/09:  616 (47.4%), UD
01/10:  530 (44.2%), UD
07/10:  636 (48.9%), UD
01/11:  627 (48.2%), UD
07/11:  840 (52.5%), UD
01/12:  920 (51.1%), UD
07/12:  857 (50.4%), 40
10/12:  UD
01/13:  710 (47.3%), UD
07/13:  886 (49.2%), UD
01/14:  985 (46.9%), UD
06/14:  823 (47.2%), UD

Offline newt

  • Member
  • Posts: 3,887
  • the one and original newt
Re: First Viral Load "Blip"
« Reply #13 on: July 15, 2012, 08:40:20 PM »
In the UK, when using the Roche test that measures to <20 copies, a reuslt of 200 or under is usually considered "undetectable" (flaky test for some reason). Officially, the line is doctors must decide what counts, but 200 is the working cut-off used for this particular test.

- matt.
"The object is to be a well patient, not a good patient"

Offline wolfter

  • Member
  • Posts: 4,752
Re: First Viral Load "Blip"
« Reply #14 on: July 16, 2012, 08:39:39 AM »
Gary, sorry to hear you're also dealing with this issue.  I always had horrible lipids also and after getting them under control, I suddenly started having high blood sugar levels. 

My doctor order additional testing, I think it's a molecule enyme test, that is a truer indication of the risk of diabetes.  Not sure if that's the true name of the test, but it's something like that.  I certainly don't want to add this disease into the mix either.  There's nothing else dietary that I can change.

I've bounced from being UD to small detectable levels for quite a while.  My doctor assures me this is not an issue and even the sensitivity of the tests can cause it.
Complacency is the enemy.  ;)  Challenge yourself daily for maximum  return on investment.

Offline Lou-ah-vull

  • Member
  • Posts: 954
Re: First Viral Load "Blip"
« Reply #15 on: July 16, 2012, 04:22:00 PM »
My doctor called this afternoon.  On Wednesday morning I am going to have blood sugar rechecked (fasting of course), A1C (has never been checked before) and something about liver and kidney enzymes (I wonder if that is the test you had Wolfer.)

I really should quit reading all this stuff on the internet because I just simply don't have enough hard information.  All it does is increase my anxiety.

Still very appreciative of any suggestions you guys have.

Gary
Diagnosed Oct. 2005
10/05:  367 (26.2%), 24556 VL
01/06:  344 (24.6%), 86299 VL
04/06:  374 (22.0%), 87657 VL
05/06:  Began HAART 05/15/06, Combivir/Kaletra
07/06:  361 (27.8%), 1299 VL
10/06:  454 (32.4%), 55 VL
01/07:  499 (38.4%), UD
02/07:  Switched to Atripla 2/8/07
04/07:  566 (37.7%), UD
08/07:  761 (42.3%), UD
06/08:  659 (47.1%), UD
01/09:  613 (43.8%), UD
07/09:  616 (47.4%), UD
01/10:  530 (44.2%), UD
07/10:  636 (48.9%), UD
01/11:  627 (48.2%), UD
07/11:  840 (52.5%), UD
01/12:  920 (51.1%), UD
07/12:  857 (50.4%), 40
10/12:  UD
01/13:  710 (47.3%), UD
07/13:  886 (49.2%), UD
01/14:  985 (46.9%), UD
06/14:  823 (47.2%), UD

Offline joeyg624

  • Member
  • Posts: 30
Re: First Viral Load "Blip"
« Reply #16 on: July 18, 2012, 11:24:38 PM »
for many years, a VL below 70 was considered as undetectable... with more sophisticated instruments these days, the threshhold for being undetectable has gone down to below 20... this is probably why a VL of 40 is showing up in your last test.
Apr 10 CD4 60 VL 256,000
May 10 CD4 130 VL 724
Aug 10 CD4 188  VL <75
Nov 10 CD4 170  VL <75
Mar 11 CD4 272 VL <48
Aug 11 CD4 272 VL <20
Nov 11 CD4 267 VL <20
Mar 12 CD4 297 VL <20
Nov 12 CD4 312 VL <20

Offline Miss Philicia

  • Member
  • Posts: 24,522
  • celebrity poster, faker & poser
Re: First Viral Load "Blip"
« Reply #17 on: July 18, 2012, 11:28:53 PM »
Actually, if I recall correctly, viral load was <400, then <200, etc. The test has been around for 15 years.
"Iíve slept with enough men to know that Iím not gay"

Offline bocker3

  • Member
  • Posts: 3,459
  • You gotta enjoy life......
Re: First Viral Load "Blip"
« Reply #18 on: July 19, 2012, 07:43:10 AM »
I recall in the earliest days of the test it was <10,000 - I was responsible for calling these results to ordering clinicians for a large HMO network in Boston back in the late 90's. 
That test has come a long way............

M
Atripla - Started 12/05
Reyataz/Norvir - Added 6/06
Labs - Pre-Meds
Sep05 T=350/25% VL98,559
Nov05 288/18%  47,564
Current Labs
May2013 691/31% <20

Offline Common_ground

  • Member
  • Posts: 288
Re: First Viral Load "Blip"
« Reply #19 on: July 19, 2012, 07:46:41 AM »
I recall in the earliest days of the test it was <10,000 - I was responsible for calling these results to ordering clinicians for a large HMO network in Boston back in the late 90's. 
That test has come a long way............

M

Thats amazing!
2011 May - Neg.
2012 June CD4:205, 16% VL:2676 Start Truvada/Stocrin
2012 July  CD4:234, 18% VL:88
2012 Sep  CD4:238, 17% VL:UD
2013 Feb  CD4:257, 24% VL:UD -viramune/truvada
2013 May CD4:276, 26% VL:UD

Offline eric48

  • Member
  • Posts: 1,211
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
Re: First Viral Load "Blip"
« Reply #20 on: July 21, 2012, 06:35:08 PM »
I will ask my doc if he has ever seen comments like : VL was undetectable
This would certainly happen if the technician verifies his machine with and un-infected blood sample, which, I would think may be part of instrumental procedure.

Many people misuse the term UD, they should either use < XX or BLQ

The following article :

Factors associated with a strictly undetectable viral load in HIV-1-infected patients.
http://www.ncbi.nlm.nih.gov/pubmed/22435457

Somehow anwers the question:

The authors have classified 3 groups:
- strictly undetectable
- detectable but below <20
- detectable but > 20 and <50

My latest lab results say detectable but below <LoQ (which is 40 in that location: hospital) ( my other lab results simply say <20, when performed in another location: commercial , private lab)

Apparently there is a group of patients that are strictly undetectable and that group can be distinguished from an other group : detectable but below <20.

Obviously, clinical pratice in well equiped labs can differenriate between SUD and what is usually refered to UD in many publications and documents, i.e. Below LoQ

Hope this clarifies things

Eric
NVP/ABC/3TC/... UD (non-infectious) ; CD4 > 1000; CD4/CD8 ~ 2.0   stock & donations : 6 months (2013: FOTO= 5d. ON 2d. OFF ; 2014: Clin. Trial NCT02157311 = 4d. ON, 3d. OFF)

Offline elf

  • Member
  • Posts: 618
Re: First Viral Load "Blip"
« Reply #21 on: July 23, 2012, 03:10:30 PM »
You should stop taking niacin, since it has been linked to causing high blood sugar.
There are other options like omega-3 that can lower your triglycerides efficiently without affecting blood sugar.


Severe reversible hyperglycemia as a consequence of niacin therapy.

http://www.ncbi.nlm.nih.gov/pubmed/8357290

I took niacin for 6 months, and although it made my HDL go high,
the blood sugar and liver enzymes got sky high as well.
It took me 3 months to bring them down to the normal values.
Now my HDL is not that high, but HDL is the least important factor in your lipid profile (total cholesterol and LDL being much more important).
« Last Edit: July 23, 2012, 03:16:25 PM by elf »
I got GRID on GRInDr

Offline Lou-ah-vull

  • Member
  • Posts: 954
Re: First Viral Load "Blip"
« Reply #22 on: July 23, 2012, 06:20:21 PM »
Wow.  First time I have seen this.  I will be seeing my doctor on Friday and I will present this information to him.  It may explain why I had dramatic improvement in my lipid profile (all across the board) but a dramatic and unexplained rise in fasting blood glucose (from a borderline high 115 to 241.)  This is very helpful.

I will post what I learn from my doctor.

Gary
Diagnosed Oct. 2005
10/05:  367 (26.2%), 24556 VL
01/06:  344 (24.6%), 86299 VL
04/06:  374 (22.0%), 87657 VL
05/06:  Began HAART 05/15/06, Combivir/Kaletra
07/06:  361 (27.8%), 1299 VL
10/06:  454 (32.4%), 55 VL
01/07:  499 (38.4%), UD
02/07:  Switched to Atripla 2/8/07
04/07:  566 (37.7%), UD
08/07:  761 (42.3%), UD
06/08:  659 (47.1%), UD
01/09:  613 (43.8%), UD
07/09:  616 (47.4%), UD
01/10:  530 (44.2%), UD
07/10:  636 (48.9%), UD
01/11:  627 (48.2%), UD
07/11:  840 (52.5%), UD
01/12:  920 (51.1%), UD
07/12:  857 (50.4%), 40
10/12:  UD
01/13:  710 (47.3%), UD
07/13:  886 (49.2%), UD
01/14:  985 (46.9%), UD
06/14:  823 (47.2%), UD

Offline Lou-ah-vull

  • Member
  • Posts: 954
Re: First Viral Load "Blip"
« Reply #23 on: July 28, 2012, 03:07:32 PM »
Update-

I saw my regular doctor for my annual physical on Friday and to review rechecked blood work regarding my elevated blood sugar.  On the retest I declined from 241 to 200, but obviously that is still high.

As others have suggested, my doctor thinks the most likely culprit is the 3000 mg of niacin I have been taking daily to improve my lipids (which it surely did.)  So, I am completely stopping the niacin for 30 days, retaking fasting lipids and blood sugar to see what happens.  Although I feared it, the doctor thought it was too soon to make a diabetes diagnosis.

If nothing else, this gives me permission to drink (and I don't mean water) while at AMG this week!

Gary
Diagnosed Oct. 2005
10/05:  367 (26.2%), 24556 VL
01/06:  344 (24.6%), 86299 VL
04/06:  374 (22.0%), 87657 VL
05/06:  Began HAART 05/15/06, Combivir/Kaletra
07/06:  361 (27.8%), 1299 VL
10/06:  454 (32.4%), 55 VL
01/07:  499 (38.4%), UD
02/07:  Switched to Atripla 2/8/07
04/07:  566 (37.7%), UD
08/07:  761 (42.3%), UD
06/08:  659 (47.1%), UD
01/09:  613 (43.8%), UD
07/09:  616 (47.4%), UD
01/10:  530 (44.2%), UD
07/10:  636 (48.9%), UD
01/11:  627 (48.2%), UD
07/11:  840 (52.5%), UD
01/12:  920 (51.1%), UD
07/12:  857 (50.4%), 40
10/12:  UD
01/13:  710 (47.3%), UD
07/13:  886 (49.2%), UD
01/14:  985 (46.9%), UD
06/14:  823 (47.2%), UD

 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.