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Author Topic: Do HIV Drugs Do Other Things, to help the body heal itself?  (Read 1243 times)

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Offline TheRoof

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The lifesaving HAART drugs have been an innovation, which of course comes with many side-effects in itself.

All though I was interested in hearing. Do HIV Drugs such as; Entry inhibitors, NRTI, NTRTI, NNRTI, Protease/Intergrase/Maturation inhibitors.

For example I heard Protease Inhibitors have ability to lower breast cancer.

Has anyone heard of anything else these drugs could "reduce" The risk of?
I would be interesting to know if there are any upsides (Perhaps for future research)

Online Jeff G

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Re: Do HIV Drugs Do Other Things, to help the body heal itself?
« Reply #1 on: July 04, 2012, 09:27:16 PM »
inhibitors.

For example I heard Protease Inhibitors have ability to lower breast cancer.

Has anyone heard of anything else these drugs could "reduce" The risk of?


Constipation for sure ;D . One of the best examples I can give is that some HIV drugs are highly active against hepatitis B . I am a chronic carrier of Hep B but have achieved complete remission due to the drug Truvada , a componet in the drug Atripla  . I haven't had a detectable viral load for Hep B in over 10 years .

Offline mecch

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Re: Do HIV Drugs Do Other Things, to help the body heal itself?
« Reply #2 on: July 05, 2012, 05:38:19 AM »
My ID doctor said that he thinks HAART is active against the mysterious retroviruses that may cause Chronic Fatigue.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline onemoretime

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Re: Do HIV Drugs Do Other Things, to help the body heal itself?
« Reply #3 on: July 08, 2012, 09:06:38 AM »
i was thinking the hep B    i have been undectable on that for 7 years since starting truvada sustive then atripla
08/04 diag 490 cd4 vl 50,000
10/25/05 436 50,513 hvb 1.1 billion
12/13/05 truvada sustiva
02/16/06 742 und, hpb 63,000
04/27/06 740 und hpb 60,000
01/05/07 458 und hvb und
03/08   470 undetectable still on atripla. Non smoking (chantex)
08/08 cd4 550 undetectable hiv, Hep B UND. Atripla
06/09  cd4 444, vl undetectable testo 130
09/09/09 CD4 687 46% UND  Testo 213 started androgel
10/12/09 cd4 682 46% und testo 597
01/12/10 cd4 842 48% und testo 434
041010 cd4 693  53% testo 492
100410 cd4 568 48% testo 523
012711 cd4 523 hcv 56 testo 596
083011 cd4 280 Hcv/HIV und
042912 cd4 158 hcv /hiv und, was on hep c for 11 months. do have ssdi filed and getting LTD
061912 cd4 151, bactrum, hep c and hiv und
071712 cd4 287 52% HIV HCV und
112012 cd4 520

Offline Ann

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Re: Do HIV Drugs Do Other Things, to help the body heal itself?
« Reply #4 on: July 08, 2012, 10:51:50 AM »
Tenofovir is the drug in Truvada that is effective against hep B. It's also available on its own and marketed as Viread.

Emtricitabine (aka FTC) is also effective against hep B and it's also found in Truvada. It's available on it's own too and marketed as Emtriva.




AZT was originally formulated in 1964 as a possible anti-cancer drug, but it proved ineffective and was shelved.

In September (1986) there was dramatic progress in the provision of medical treatment for AIDS, when early results of clinical tests showed that a drug called azidothymidine (AZT) slowed down the attack of HIV. AZT was first synthesised in 1964 as a possible anticancer drug but had proved ineffective.

The AZT clinical trial divided patients into two groups: one received AZT and the other received a placebo. At the end of six months, only one patient in the AZT group had died, whilst there were 19 deaths among the placebo group. The clinical trial was stopped early, because it was thought to be unethical to deny the patients of the placebo groups a better chance of survival.
(source)




The following information is taken directly from our meds information pages. Click on the drug name to read more.

Proleukin:

    The drug is only approved for the treatment of certain types of cancer. It is still considered an experimental drug for HIV-related therapy and it has not yet been evaluated by the U.S. Food and Drug Administration (FDA) for use in people living with the virus.

Interleukin-7 (IL-7):

    IL-7 is being studied as a treatment for HIV, viral hepatitis and cancer.

Droxia:

    Hydroxyurea is approved as an antineoplastic. Antineoplastics are used to treat cancer. Hydroxyurea is used to treat melanoma (a type of skin cancer), chronic myelocytic leukemia (CML), cancer of the ovary, and primary squamous cell (skin) cancer of the head and neck.
 
    Hydroxyurea has also been studied as a potential treatment for HIV infection. Although it is not approved by the U.S. Food and Drug Administration for this purpose, some HIV-positive people do use it, usually in combination with approved anti-HIV drugs.

Aralen:

    Aralen is an anti-parasitic drug used to treat malaria. It is a generic drug manufactured widely.
     
    Aralen also exerts an effect on the immune system, reducing cellular activation and overall system inflammation. Cellular activation has been linked to faster HIV disease progression and poorer CD4 cell recovery after initiating antiretroviral (ARV) therapy. Inflammation has been linked to worsening HIV disease, and to non-HIV-related conditions that include cardiovascular disease, liver disease and certain cancers.
     
    Currently, Aralen is in early-state testing to determine its potency at reducing HIV-specific cellular activation and to potentially delay the need for a person to begin ARV therapy.

Plaquenil:

    Plaquenil is an anti-parasitic drug used to treat malaria. It is also used as an anti-inflammatory drug to treat lupus and rheumatoid arthritis. It is a generic drug manufactured widely.
     
    Plaquenil also exerts an effect on the immune system, reducing cellular activation and overall system inflammation. Cellular activation has been linked to faster HIV disease progression and poorer CD4 cell recovery after initiating antiretroviral (ARV) therapy. Inflammation has been linked to worsening HIV disease, and to non-HIV-related conditions that include cardiovascular disease, liver disease and certain cancers.
     
    Currently, Plaquenil is in early-state testing to determine its potency at reducing HIV-specific cellular activation and to potentially delay the need for a person to begin ARV therapy.




That's it as far as I'm aware.



edited to add Emtriva info
« Last Edit: July 08, 2012, 12:00:05 PM by Ann »
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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline Ann

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Re: Do HIV Drugs Do Other Things, to help the body heal itself?
« Reply #5 on: July 08, 2012, 10:57:44 AM »
Basically, hiv meds help the body heal simply by doing their primary function - stopping hiv's life cycle at various points in that cycle. Different classes of meds stop hiv replication at different points in the cycle. It's all explained in the Lesson I linked to above.

When the meds are taking care of hiv, your body can then focus on other things rather than fighting (a losing) battle against hiv 24/7. That's what leads to the healing.
Condoms are a girl's best friend

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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline newt

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Re: Do HIV Drugs Do Other Things, to help the body heal itself?
« Reply #6 on: July 08, 2012, 02:31:53 PM »
Well said Ann - matt
"The object is to be a well patient, not a good patient"

 


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