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Author Topic: quad pill  (Read 2976 times)

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Offline surf18

  • Member
  • Posts: 525
quad pill
« on: May 13, 2012, 11:23:08 AM »
anyone thinking of switching to it when it becomes approved later this summer and why would you switch?
personally I'm thinking about it, my dr said i should do well on it and i like the one a day option. but we ll see.

Offline Miss Philicia

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  • Posts: 23,899
  • celebrity poster, faker & poser
Re: quad pill
« Reply #1 on: May 13, 2012, 05:40:24 PM »
What are you on now?
"Iíve slept with enough men to know that Iím not gay"

Offline leatherman

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  • Posts: 6,059
  • Google and HIV meds are Your Friends
Re: quad pill
« Reply #2 on: May 13, 2012, 06:31:40 PM »
several regimens are already once a day dosing, and taking 1 pill really isn't that much different from taking 3 or so. in the vein of "if it ain't broke, don't fix it", why would anyone want to change from an already working regimen to something else?
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline Hellraiser

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  • Posts: 4,136
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Re: quad pill
« Reply #3 on: May 13, 2012, 06:33:00 PM »
several regimens are already once a day dosing, and taking 1 pill really isn't that much different from taking 3 or so. in the vein of "if it ain't broke, don't fix it", why would anyone want to change from an already working regimen to something else?

To limit side effects, I swapped from Atripla to Complera for a lack of side effects.  Complera is letting me sleep a lot better but it HAS to be taken with a meal which is frustrating, because if you're not hungry it doesn't matter.  If the quad pill is similarly without side effects and no meal requirement I would want to swap to it.

Offline lost_boy

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  • Posts: 105
Re: quad pill
« Reply #4 on: May 13, 2012, 06:38:58 PM »
What is this quad pill? Not heard of it til now!

But then I don't pay close enough attention to these things, could spend all day obsessing otherwise  :P

Offline buginme2

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  • Posts: 2,834
Re: quad pill
« Reply #5 on: May 13, 2012, 07:55:54 PM »
I have been thinking about switching off Atripla lately although I haven't made any firm decision about it.  I probably won't take Complera because I take heartburn medication sometimes and it's contradictory.  I have thought about the quad pill but with it being so new I'm not sold just yet.  There is word now that it can cause Kidney problems (even more so than just Truvada) so that's a concern.

Decisions decisions

Offline leatherman

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  • Google and HIV meds are Your Friends
Re: quad pill
« Reply #6 on: May 13, 2012, 08:02:19 PM »
To limit side effects
which implies a NOT properly working regimen ie it would be broken and deserving of a change or something to reduce the side effects. ;)

but it HAS to be taken with a meal which is frustrating, because if you're not hungry it doesn't matter.  If the quad pill is similarly without side effects and no meal requirement I would want to swap to it.
you skip dinner so often that this would be a problem? ok  ;)
I take my R/N/T every night with dinner
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline surf18

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  • Posts: 525
Re: quad pill
« Reply #7 on: May 13, 2012, 08:26:58 PM »
miss p- I'm on truvada/selzentry for about a year and a half

yea thats what I'm thinking sometimes too is if I'm doing ok why switch. though just one pill in morning is cool. ditching that night time pill would be nice.
atripla im not gonna do because I'm already nuts, and complera i can't do because of the acid reflux meds.
on the kidney thing, my dr told me the other day that tests sometimes show that an elevated kidney something or another that is a false result? i don't know.
might wait for it when its made with the new truvada light.

Offline mikeyb39

  • Member
  • Posts: 921
Re: quad pill
« Reply #8 on: May 13, 2012, 11:53:38 PM »
i'm really liking my new combo, the isentress and boosted Prezista, i have zero side-effects really.  This is something my doctor is experimenting with me with only a dual combo versus triple combo.  I'm keeping my fingers crossed that all is still well and undetectable, will have labs done soon since been over 4 months.  I'd sure like to keep off the Truvada at all costs since it did a number on my nerves.
11/02/2010  cd4-251, vl-591000
12/09/2010  started Atripla
02/18/2011  cd4-425, vl-800
06/10/2011  cd4-447, vl-70
10/10/2011  cd4-666, vl-80
01/05/2012  swiched med (prezista,norvir ,isentress, )
02/10/2012  cd4-733, vl-UD  Viread removed
06/10/2012  cd4-614, vl-UD
12/14/2012  cd4-764, vl-UD
09/01/2013  cd4-785, vl-UD
03/06/2014. cd4- 1078, VL-UD

Offline Pozitively Moving Forward

  • Member
  • Posts: 14
Re: quad pill
« Reply #9 on: May 18, 2012, 06:47:12 PM »
Hello Ladies and Gents...
I am currently on a double blind clinical trial with the 'quad' and 'quad2'.  Diagnosed January 1, 2012.  Started '?quad?' April 24th with viral load 33K and CD4 @ 331.  The side effects are nonexistent!!  I spoke to my clinical trial director 5/22/12 and was informed my viral load was at or below 50.  My partner is waiting to start meds till quad is officially released later this year.
1/11/12 Test Positive HIV CD4 - 434 VL - 58K
2/8/12  CD4 316 VL- 62K (15%)
4/24/12 CD4 - 333 VL-33K (22.3%) 
5/8/12   CD4 - 419 VL - 124  (23.1%)
5/22/12 CD4 - 456 VL - 30  (24.5%)
6/19/12 CD4 - 593 VL - >20 (26.1%)
7/17/12 CD4 - 463 VL - >20 (28.1%)
8/14/12 CD4 - 476 VL - >20 (32.2%)

Offline surf18

  • Member
  • Posts: 525
Re: quad pill
« Reply #10 on: May 18, 2012, 09:40:21 PM »
Thanks for the update. Be sure to keep posting your lab results. Thanks

Offline Pozitively Moving Forward

  • Member
  • Posts: 14
Re: quad pill
« Reply #11 on: May 23, 2012, 02:32:55 PM »
Trial Director numbers were slightly off.
4/24/12 started Quad
Viral Load - 33,000
CD4 - 331
5/8/12
Viral Load - 124
CD4 - 419
Doctor says my results are very typical with the Quad Pill.

1/11/12 Test Positive HIV CD4 - 434 VL - 58K
2/8/12  CD4 316 VL- 62K (15%)
4/24/12 CD4 - 333 VL-33K (22.3%) 
5/8/12   CD4 - 419 VL - 124  (23.1%)
5/22/12 CD4 - 456 VL - 30  (24.5%)
6/19/12 CD4 - 593 VL - >20 (26.1%)
7/17/12 CD4 - 463 VL - >20 (28.1%)
8/14/12 CD4 - 476 VL - >20 (32.2%)

Offline surf18

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  • Posts: 525
Re: quad pill
« Reply #12 on: May 23, 2012, 08:53:15 PM »
wow fantastic results.thanks!
you still feel good?

Offline Pozitively Moving Forward

  • Member
  • Posts: 14
Re: quad pill
« Reply #13 on: May 24, 2012, 08:01:03 PM »
Was extremely pleased with results.  Felt good to give my parents some good news.  Side effects are still nil from the meds.  And I think the overall 'crappy' feeling I've had since contracting is slowly starting to lift.  My experience with ALL this is extremely limited, but happy to share all.  Best wishes man. 
1/11/12 Test Positive HIV CD4 - 434 VL - 58K
2/8/12  CD4 316 VL- 62K (15%)
4/24/12 CD4 - 333 VL-33K (22.3%) 
5/8/12   CD4 - 419 VL - 124  (23.1%)
5/22/12 CD4 - 456 VL - 30  (24.5%)
6/19/12 CD4 - 593 VL - >20 (26.1%)
7/17/12 CD4 - 463 VL - >20 (28.1%)
8/14/12 CD4 - 476 VL - >20 (32.2%)

Offline Pozitively Moving Forward

  • Member
  • Posts: 14
Re: quad pill
« Reply #14 on: May 31, 2012, 02:39:01 PM »
Currently been on the Quad/Quad2 for just over a month. (4/24-5/31)  Lab results as of 5/22...CD4 - 419 and VL -  UD @ 30.  Still have not experienced any side effects and overall I am feeling great.  Doctor heading the study says my results are very typical with the Quad.   
1/11/12 Test Positive HIV CD4 - 434 VL - 58K
2/8/12  CD4 316 VL- 62K (15%)
4/24/12 CD4 - 333 VL-33K (22.3%) 
5/8/12   CD4 - 419 VL - 124  (23.1%)
5/22/12 CD4 - 456 VL - 30  (24.5%)
6/19/12 CD4 - 593 VL - >20 (26.1%)
7/17/12 CD4 - 463 VL - >20 (28.1%)
8/14/12 CD4 - 476 VL - >20 (32.2%)

Offline Pozitively Moving Forward

  • Member
  • Posts: 14
Re: quad pill
« Reply #15 on: June 25, 2012, 01:25:21 PM »
Just received latest labs.
VL less then 20 and CD4 593 26.1%
Started meds 2 months ago.  I can now identify the side effects from meds.  I dose everyday between 11am and Noon.
1 hour after meds, slight headache, light/moderate gas, mild Nausea most days (rarely moderate) diarrhea most days, and occasional flushing of the face.  And not sure why or what's causing but both right a left legs are slightly numb at the shin down to top of feet.  Doctor seemed slightly perplexed, but said will wait till next appt. in July to react if still evident. wtf?!
Overall the effects are all mild and easily tolerable, but it would nice to have a day/week where I felt GREAT again....Hope this helps guys, enjoy the week.

Also, since I contracted in December I have constant Indigestion.  The kind where you need to burp but cannot.  Does anyone know any remedy preferably natural that might help or at least take the edge off. 
« Last Edit: June 25, 2012, 01:37:42 PM by Pozitively Moving Forward »
1/11/12 Test Positive HIV CD4 - 434 VL - 58K
2/8/12  CD4 316 VL- 62K (15%)
4/24/12 CD4 - 333 VL-33K (22.3%) 
5/8/12   CD4 - 419 VL - 124  (23.1%)
5/22/12 CD4 - 456 VL - 30  (24.5%)
6/19/12 CD4 - 593 VL - >20 (26.1%)
7/17/12 CD4 - 463 VL - >20 (28.1%)
8/14/12 CD4 - 476 VL - >20 (32.2%)

Offline surf18

  • Member
  • Posts: 525
Re: quad pill
« Reply #16 on: June 25, 2012, 08:39:19 PM »
ugh this was an ugly post. interesting what your going through now. so i guess its not a slam dunk to switch meds for me.

Offline gadawg1979

  • Member
  • Posts: 141
Re: quad pill
« Reply #17 on: June 29, 2012, 12:45:04 AM »
To limit side effects, I swapped from Atripla to Complera for a lack of side effects.  Complera is letting me sleep a lot better but it HAS to be taken with a meal which is frustrating, because if you're not hungry it doesn't matter.  If the quad pill is similarly without side effects and no meal requirement I would want to swap to it.

I have found that if you are not good and do not take it with a good meal you better have lots of good reading as you will set up camp in the john.
Diagnosed March 2012
Initial CD4- 156 VL 200K (started Complera) Genotype test no resistance
First labs on meds CD4- 246 VL 2K Taken after 30 days on Complera
90 Day labs VL 306 No CD4 Drawn
8/21/2012 CD4 474 VL Undetectable (40) %20.6
11/27/2012 CD 4 522 VL Undetectable (40)
2/14/2013 CD 4 464 VL Undetecable (30) 19.6%
6/8/3013 CD 4 528 VL Undetectable (30)
9/24/2013 CD 4 546 VL Undetectable (40)
1/30/2014 CD4 560 VL Undetectable (40) 22 %
6/19/2014 CD4 584 Vl Undetecable (30)

Offline Hellraiser

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  • Posts: 4,136
  • Semi-misanthropic
Re: quad pill
« Reply #18 on: July 02, 2012, 09:49:26 PM »
I have found that if you are not good and do not take it with a good meal you better have lots of good reading as you will set up camp in the john.

The Quad pill or Complera?

 


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